Results 201 to 210 of about 89,289 (243)
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Auditory hair cell innervational patterns in lizards
Journal of Comparative Neurology, 1988AbstractThe pattern of afferent and efferent innervation of two to four unidirectional (UHC) and two to nine bidirectional (BHC) hair cells of five different types of lizard auditory papillae was determined by reconstruction of serial TEM sections. The species studies were Crotaphytus wislizeni (iguanid), Podarcis (Lacerta) sicula and P.
Malcolm R. Miller, Janet Beck
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Aligned Organization of Synapses and Mitochondria in Auditory Hair Cells
Neuroscience Bulletin, 2021Recent studies have revealed great functional and structural heterogeneity in the ribbon-type synapses at the basolateral pole of the isopotential inner hair cell (IHC). This feature is believed to be critical for audition over a wide dynamic range, but whether the spatial gradient of ribbon morphology is fine-tuned in each IHC and how the ...
Shengxiong Wang +11 more
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Auditory Hair Cells and Sensory Transduction
2017The organs of the vertebrate inner ear respond to a variety of mechanical stimuli: semicircular canals are sensitive to angular velocity, the saccule and utricle respond to linear acceleration (including gravity), and the cochlea is sensitive to airborne vibration, or sound.
Jeffrey R. Holt +1 more
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Somatostatin and gentamicin‐induced auditory hair cell loss
The Laryngoscope, 2009AbstractObjective/Hypothesis:Hair cells of the mammalian auditory system do not regenerate, and therefore their loss leads to irreversible hearing loss. Aminoglycosides, among other substances, can irreversibly damage hair cells. Somatostatin, a peptide with hormone/neurotransmitter properties, has neuroprotective effects by binding to its receptor. In
Caelers, Antje +3 more
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Bifurcation and Chaos of Spontaneous Oscillations of Hair Bundles in Auditory Hair Cells
International Journal of Bifurcation and Chaos, 2021Various spontaneous oscillations and Hopf bifurcation have been observed in hair bundles of auditory hair cells, which play very important roles in the auditory function. In the present paper, the bifurcations and chaos of spontaneous oscillations of hair bundles are investigated in a theoretical model to explain the experimental observations. Firstly,
Ben Cao +3 more
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Auditory amplification: outer hair cells pres the issue [PDF]
Trends in Neurosciences, 2003 Active feedback mechanisms in the ears of mammals amplify and tune the auditory response to sound stimuli, allowing these organisms to enjoy both exquisite sensitivity and sharp frequency selectivity. A requisite component of this feedback pathway has recently been identified.
Gwenaëlle S. G. Géléoc +1 more
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Two Components of Transducer Adaptation in Auditory Hair Cells
Journal of Neurophysiology, 1999Mechanoelectrical transducer currents in turtle auditory hair cells adapted to maintained stimuli via a Ca2+-dependent mechanism characterized by two time constants of ∼1 and 15 ms. The time course of adaptation slowed as the stimulus intensity was raised because of an increased prominence of the second component. The fast component of adaptation had a
Robert Fettiplace +2 more
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Auditory collusion and a coupled couple of outer hair cells [PDF]
Nature, 1999 The discrepancies between measured frequency responses of the basilar membrane in the inner ear and the frequency tuning found in psychophysical experiments led to Bekesy's idea of lateral inhibition in the auditory nervous system. We now know that basilar membrane tuning can account for neural tuning, and that sharpening of the passive travelling wave
Joseph Santos-Sacchi, Hong-Bo Zhao
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Recent insights into regeneration of auditory and vestibular hair cells
Current Opinion in Neurology, 1998Advances in hair cell regeneration are progressing at a rapid rate. This review will highlight and critique recent attempts to understand some of the cellular and molecular mechanisms underlying hair cell regeneration in non-mammalian vertebrates and efforts to induce regeneration in the mammalian inner ear sensory epithelium.
Edwin W. Rubel +2 more
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Sorting of actin isoforms in chicken auditory hair cells
Journal of Cell Science, 1997Most nonmuscle cells of higher vertebrates contain two different actin isoforms, beta- and gamma-cytoplasmic actin. The beta-isoform is with few exceptions the predominant isoform in nonmuscle cells and tissues. Perturbation of the beta:gamma ratio has been shown to affect the organization of bundled actin filaments indicating that the beta- and gamma ...
Detlev Drenckhahn, D. Hofer, W. Ness
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