Results 61 to 70 of about 4,824,676 (233)

The hair cell analysis toolbox is a precise and fully automated pipeline for whole cochlea hair cell quantification.

open access: yesPLoS Biology, 2023
Our sense of hearing is mediated by sensory hair cells, precisely arranged and highly specialized cells subdivided into outer hair cells (OHCs) and inner hair cells (IHCs).
Christopher J Buswinka   +4 more
doaj   +1 more source

Introduction of Transmembrane Inner Ear (tmie) Gene Can Recover the Hearing Impairment and Abnormal Behavior in the Circling Mouse [PDF]

open access: yes, 2008
The spontaneous mutant circling mouse (cir/cir) shows a circling behavior and hearing loss. We produced transgenic mice overexpressing the causative gene, transmembrane inner ear (tmie), for the phenotypic rescue of the circling mouse.
Mi Jung Shin   +13 more
core  

The CD2 isoform of protocadherin-15 is an essential component of the tip-link complex in mature auditory hair cells [PDF]

open access: yes, 2014
International audienceProtocadherin-15 (Pcdh15) is a component of the tip-links, the extracellular filaments that gate hair cell mechano-electrical transduction channels in the inner ear.
Bahloul, Amel   +32 more
core   +1 more source

Transient Sleep Deprivation Induces Persistent Auditory Neuropathy via ROS‐Initiated Neuroinflammation and BK Channel Suppression

open access: yesAdvanced Science, EarlyView.
Sleep disturbance severity closely tracks hearing loss in a clinical cohort, yet the mechanistic link remains unclear. Acute sleep deprivation is shown to trigger transient cochlear oxidative stress that switches into a self‐sustaining neuroinflammatory state, suppressing BK channels and causing irreversible synaptopathy.
Dan Chen   +11 more
wiley   +1 more source

Visual-auditory Volume Rendering of Scalar Fields

open access: yes, 2019
Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria University, Newcastle upon Tyne, UK.Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria ...
Alexander Pasko   +7 more
core   +1 more source

Abstract Representation of Movement Parameters in Basal Ganglia Output

open access: yesAdvanced Science, EarlyView.
The basal ganglia output provides a scalable velocity/position signal across behavioral contexts, supporting the idea that these variables are represented in the brain as abstract entities rather than as fixed changes in joint angles or specific sets of body effectors.
Ana Silvia Báez‐Cordero   +3 more
wiley   +1 more source

Stem-cell therapy for hearing loss: are we there yet?

open access: yesBrazilian Journal of Otorhinolaryngology, 2019
Introduction: Mammalian hair cells and auditory neurons do not show regenerative capacity. Hence, damage to these cell types is permanent and leads to hearing loss. However, there is no treatment that re-establishes auditory function.
Luiz Gustavo Dufner-Almeida   +5 more
doaj   +1 more source

The in vitro plasticity of hair follicle dermal and mesenchymal stem cells [PDF]

open access: yes, 2008
Stem cells from the hair follicle are an easily accessible population of cells that have a broad in vitro developmental capabilities and potential for autologous replacement of damaged adult tissue.
Emmerson, Robert
core  

Auditory Displays for Automated Driving — Challenges and Opportunities

open access: yes, 2019
Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria University, Newcastle upon Tyne, UK.Presented at the 25th International Conference on Auditory Display (ICAD 2019) 23-27 June 2019, Northumbria ...
Lachmann, Max   +7 more
core   +1 more source

Input-driven components of spike-frequency adaptation can be unmasked in vivo [PDF]

open access: yes, 2004
Spike-frequency adaptation affects the response characteristics of many sensory neurons, and different biophysical processes contribute to this phenomenon.
Gollisch, Tim, Herz, Andreas V. M.
core   +1 more source

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