Results 101 to 110 of about 5,630,806 (253)

Jaw‐specific stem cell dynamics are associated with distinct enamel architecture in mouse incisors

Developmental Dynamics, EarlyView.
Abstract Background The continuously growing mouse incisor serves as a model for stem cell‐driven tooth renewal. Although mice possess maxillary and mandibular incisors, most studies have focused on the mandible. Potential differences in structure and renewal between these serially homologous organs remain insufficiently characterized.
Elias Shahin, Jihan Asmar, Sanako Takano, Jimmy K. Hu, Amnon Sharir   +4 more
wiley   +1 more source

Hedgehog signaling reprograms hair follicle niche fibroblasts to a hyper-activated state

, 2022
Hair follicle stem cells are regulated by dermal papilla fibroblasts, their principal signaling niche. Overactivation of Hedgehog signaling in the niche dramatically accelerates hair growth and induces follicle multiplication in mice.
오지원
core   +1 more source

Under‐Explored Species, Breeds and Cell Types With Potential for Cultivated Meat Production

Food Bioengineering, EarlyView.
This graphical abstract illustrates how the strategic selection of overlooked cell lines from novel species and specific agricultural breeds can help overcome current manufacturing bottlenecks in cultivated meat production. The schematic links the concept of an ‘ideal cell line’ to four key bioprocessing and product advantages that can be optimised ...
William Gordon‐Petrovskii, Maanasa Ravikumar, Travis Callue, Maria Laura Vieri, Michael Sulu, Gary J. Lye, Mariana Petronela Hanga   +6 more
wiley   +1 more source

Androgenetic alopecia: new insights into the pathogenesis and mechanism of hair loss [v1; ref status: indexed, http://f1000r.es/5ar]

F1000Research, 2015
The hair follicle is a complete mini-organ that lends itself as a model for investigation of a variety of complex biological phenomena, including stem cell biology, organ regeneration and cloning.
Rodney Sinclair, Niloufar Torkamani, Leslie Jones   +2 more
doaj   +1 more source

Stem cells cycle in the hair follicle [PDF]

Nature Reports Stem Cells, 2008
An intestinal marker of cycling cells, Lgr5, helps identify surprising activity in the hair follicle ...
openaire   +1 more source

Somatic cell reprogramming for Parkinson's disease treatment

Ibrain, Volume 11, Issue 1, Page 59-73, Spring 2025.
The fundamental purpose of cell reprogramming to treat Parkinson's disease is to generate dopaminergic neurons (DAN) and do transplantation. There are two ways to accomplish this. One method is to induce cells into induced DA neurons (iDAN) directly or to induce cells into induced pluripotent stem cells and ultimately into iDAN in vitro. Another option
Xiaozhuo Li, Kevin Fang, Fengping Wang
wiley   +1 more source

Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin

, 2010
Mammalian epidermis consists of three self-renewing compartments: the hair follicle, the sebaceous gland, and the interfollicular epidermis. We generated knock-in alleles of murine Lgr6, a close relative of the Lgr5 stem cell gene.
Vries, R.G.J., van de Wetering, M.L., Clevers, H., Stange, D.E., Toftgard, R., Barker, N., van den Born, M.M.W., Kasper, M., Snippert, H.J.G., van Es, J.H., Jaks, V., Haegebarth, A., Begthel, H.L.   +12 more
core   +1 more source

Human biomarker navigator

iMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li, Qian Zhang, Zijie Wang, Zeping Gui, Jing Liu, Jingda Li, Maojun Jiang, Zukang Chang, Qingqing Han, Bendong Yang, Tariq Saeed, Jun Li, Jinghan Jia, Chenghu Song, Tong Shao, Tianhuan Peng, Xueying Zhang, Pingping Guo, Jun Luo, Gangao Yang, Yuan Wan, Gokhan Zengin, Quan Yuan, Lingru Li, Xiaohui Fan, Yang Luo, Lvyun Zhu, Yanfei Zheng, Wenjun Mao, Wenlong Sun   +29 more
wiley   +1 more source

Mesenchymal stem cell-derived exosomes promote scalp rejuvenation through type XVII collagen regulation via the miR-21-5p/DKK2/Wnt pathway

Frontiers in Cell and Developmental Biology
BackgroundHair follicle aging is driven by COL17A1 proteolysis in hair follicle stem cells (HFSCs). Mesenchymal stem cell (MSC)-derived exosomes show promise in tissue regeneration, but their effects on COL17A1 and hair follicle aging remain unexplored ...
Shiyue Cui, Yuanyuan Huang, Duo Zeng, Jie Li, Chun Tang   +4 more
doaj   +1 more source

Gymnema sylvestre: Bioactive constituents, health benefits, and emerging applications in nutraceuticals and functional foods

JSFA reports, EarlyView.
Abstract Gymnema sylvestre (Retz.) R.Br. ex‐Schult., commonly known as “gurmar” or “sugar destroyer,” belongs to the Apocynaceae family and is traditionally used in Ayurveda for diabetes management. This review synthesizes ethnomedicinal evidence with contemporary pharmacological studies, to evaluate the therapeutic properties and mechanistic actions ...
Faiza Saeed, Muhammad Tauseef Sultan, Hassan Raza, Ahmad Mujtaba Noman, Nimra Haroon, Entessar Mohammad Al Jbawi   +5 more
wiley   +1 more source