Iron and Other Metal Ions in Human Health and Disease
MedComm, Volume 7, Issue 10, October 2026.Iron, copper, zinc, and calcium orchestrate cellular function through distinct yet cooperative mechanisms: redox‐active iron and copper cycle between oxidation states to act as Fenton catalysts and electron carriers in oxidative phosphorylation (OXPHOS); redox‐inert zinc serves as a structural component of zinc‐finger proteins and a catalytic cofactor ...
Xiaofeng Dai, Jitian Li
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Role of the soluble epoxide hydrolase in the hair follicle stem cell homeostasis and hair growth. [PDF]
Pflugers Arch, 2022 Naeem Z +7 more
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MedComm, Volume 7, Issue 10, October 2026.The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
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Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration. [PDF]
Chin Med, 2023 Du H +9 more
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Cancer Science, Volume 117, Issue 10, Page 2752-2768, October 2026.KRTAP2‐3 drives OSCC progression by sustaining both mesenchymal and proliferative properties through KRAS signaling. Loss of KRTAP2‐3 induces MET, suppresses KRAS pathway activation, and markedly reduces tumor cell proiferation and tumor formation as illustarted in Figure.
Qianqian Miao +6 more
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Correction: Traditional Chinese Medicine Shi-Bi-Man regulates lactic acid metabolism and drives hair follicle stem cell activation to promote hair regeneration. [PDF]
Chin Med, 2023 Du H +9 more
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Cancer Science, Volume 117, Issue 10, Page 2790-2802, October 2026.Nestin‐driven green fluorescent protein (ND‐GFP) expressing peripheral blood vessels and nerves in the subcutaneous tissue of the ND‐GFP mice extended into the transplanted melanoma such that ND‐GFP was enhanced at the margin of the melanoma compared to the tumor‐free side.
Koya Obara +8 more
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Timely Wound Healing Is Dependent on Endothelial but Not on Hair Follicle Stem Cell Toll-Like Receptor 2 Signaling. [PDF]
J Invest Dermatol, 2022 Xiong L +4 more
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Smurf2-induced degradation of SMAD2 causes inhibition of hair follicle stem cell differentiation. [PDF]
Cell Death Discov, 2022 Lin B +6 more
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mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation
Experimental Dermatology, Volume 35, Issue 10, October 2026.ABSTRACT Skin aging is a multifactorial process characterized by the progressive decline of tissue structure, function and regenerative capacity. Although numerous interventions have been developed to improve the clinical manifestations of aging, most primarily alleviate downstream consequences rather than directly targeting the molecular mechanisms ...
Fabiana Boncimino +3 more
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