Results 71 to 80 of about 5,630,806 (253)

Neural Stem Cells Restore Hair Growth through Activation of the Hair Follicle Niche

Cell Transplantation, 2016
Several types of hair loss result from the inability of hair follicles to initiate the anagen phase of the hair regeneration cycle. Modulating signaling pathways in the hair follicle niche can stimulate entry into the anagen phase.
Insik Hwang, Kyung-Ah Choi, Hang-Soo Park, Hyesun Jeong, Jeong-Ok Kim, Ki-Cheon Seol, Han-Jin Kwon, In-Hyun Park, Sunghoi Hong Ph.D.   +8 more
doaj   +1 more source

Comparative characterization of hair follicle dermal stem cells and bone marrow mesenchymal stem cells

, 2022
S.49-60We compared the growth and differentiation characteristics of hair follicle-derived dermal stem cells with bone marrow mesenchymal stem cells (MSCs). Follicular dermal cells were isolated from whisker hairs of Wistar rats and bone marrow MSCs were
Hoogduijn, M.J., Gorjup, E., Genever, P.G.   +2 more
core   +1 more source

Application and Single‐Cell Regulation Mechanism of Engineered EVs Combined With 4D‐Printed Hydrogel for Infected Burn Repair

Advanced Science, EarlyView.
4D bioprinted hydrogel loaded with FGF2‐modified extracellular vesicles (4D@F‐EVs) targets dermal fibroblasts and elevates local wound FGF2 levels via sustained release of F‐EVs. It activates PI3K‐Akt signaling, restores critical KGF+ fibroblast–KGFR+ keratinocyte crosstalk, enhances robust angiogenesis and collagen deposition to efficiently repair ...
Xiaomin Wang, Xiaoyan Li, Xiao Xu, Kelun Zhang, Fengjiao Yu, Zhen Shang, Nailong Pan, Junlin Lv, Yiwei Xu, Yan Tang, Liang Zhang, Xiaotong Li, Taoyi Wang, Jing Tao, Jiaxu Song, Mengyu Zhang, Xin Ma, Dan Han, Xiaoying Kong, Wenhua Xu   +19 more
wiley   +1 more source

Dermal T cell immunity and key regulatory signaling pathways: Implications in immune-mediated alopecia and hair regeneration

Genes and Diseases
Mammalian hair follicles undergo periodic regeneration, with recent research highlighting the immunological niche as a critical regulator of stem cell activity and hair follicle regeneration.
Nana Tao, Qingru Sun, Yuyuan Ying, Yitao Wang, Jianli Gao   +4 more
doaj   +1 more source

Defining Hair Follicles in the Age of Stem Cell Bioengineering [PDF]

Journal of Investigative Dermatology, 2007
One challenge faced by stem cell biologists is the bioengineering of an organ. Ehama et al. (2007, this issue) used cells derived from human and rodent epidermis and dermal papilla to reconstitute hair-follicle mini-organs. Some result in hair follicles; others are hair follicle-like.
Chuong, Cheng-Ming, Cotsarelis, George, Stenn, Kurt   +2 more
openaire   +2 more sources

Molecular and cellular basis of Exogen and Anagen induction [PDF]

, 2007
The hair follicle has the unique capacity to pass through periods of growth, regression and rest before regenerating itself to restart the cycle. This dynamic cycling capacity enables animals to change their coats, and for hair length to be controlled at
Claire Alexandra Higgins,
core  

Notch promotes neural lineage entry by pluripotent embryonic stem cells [PDF]

, 2006
A central challenge in embryonic stem (ES) cell biology is to understand how to impose direction on primary lineage commitment. In basal culture conditions, the majority of ES cells convert asynchronously into neural cells.
Smith, Austin G, Austin G Smith, Heavey Barry, Alexandra Benchoua, Benchoua, Alexandra, Smith, Austin,, Benchoua Alexandra, Sally Lowell, Smith Austin G, Lowell, Sally; id_orcid, Smith, Austin, G., Lowell Sally, Lowell, Sally, Heavey, Barry, Barry Heavey   +14 more
core   +1 more source

Dual‐Targeting Biomimetic Nanozymes Loaded Microneedle Patch Promotes Scarless Wound Healing Through Anti‐Inflammatory and Anti‐Fibrotic Effects

Advanced Science, EarlyView.
This study developed a dual‐targeting biomimetic nanozyme hybrid system (Cu‐CeO2@ABs‐FTP) and integrated it with HAMA hydrogel to fabricate a microneedle patch (CAF@MN). The patch promotes fibroblast‐mediated wound repair, targets macrophages to induce M2 polarization, and targets myofibroblasts to exert anti‐fibrotic effects, thereby enabling rapid ...
Hongyi Zhang, Jinwei Li, Shan Hua, Shengming Wu, Chenlong He, Yuan Zhu, Ming Yin, Han Zhou, Huawei Liu, Chika Hasegawa, Jun Lyu, Keyue Xiao, Hua Jiang, Yilong Wang, Yuxin Qian   +14 more
wiley   +1 more source

Differences in Growth Response of Human Hair Follicle Mesenchymal Stem Cells to Herbal Extracts and a Growth Factor

Journal of Medicinal Plants, 2018
Background: One of the key questions in biochemistry is why cell becomes aged and what are the involved factors? Why cell growth is stopped after some divisions and cells become senescent?
HR Ahmadi Ashtiani, F Salehinia, H Rastegar, AA Allameh, Sh Rezazadeh   +4 more
doaj  

Neurotrophic Effects of Silibinin on Differentiation of Hair Follicle Stem Cells to Neurons [PDF]

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2010
Background and Objectives: Hair Follicle Bulge region due to its availability and abundance is one of the areas which is easily accessible to Multi-potent stem cells that expresses Nestin marker (neuronal stem cells protein).
Asalgoo S. (MSc)1; (PhD)2; (PhD)3; (PhD)3; (MSc)4;, Nobakht M., Rahbar Roshandel N., Mousavizadeh K., Najafzadeh N., Kordestani Shargh B.   +5 more
doaj