Results 81 to 90 of about 11,390 (192)

The canine era : the rise of a biomedical model [PDF]

, 2016
Since the annotation of its genome a decade ago, the dog has proven to be an excellent model for the study of inherited diseases. A large variety of spontaneous simple and complex phenotypes occur in dogs, providing physiologically relevant models to ...
Abecasis, Agler, Ahonen, Ahram, Arendt, Awano, Axelsson, Bannasch, Baranowska Korberg, Boyko, Broeckx, Cadieu, Cerda-Gonzalez, Clark, Cooke, Daetwyler, de Sluis, Decker, Downs, Dreger, Drogemuller, Drogemuller, ENCODE Project Consortium, Everts, FANTOM Consortium, Forman, Forman, Freedman, French FMF Consortium, Genome of the Netherlands Consortium, Grall, Grundberg, Guo, Hayward, Hoeppner, Hytonen, Karlsson, Karlsson, Ke, Kim, Kirkness, Koskinen, Kyostila, Lavrijsen, Lavrijsen, Lee, Leegwater, Lequarre, Lin, Lindblad-Toh, Liu, Lohi, Massey, Merveille, Motohashi, Newton, Olsson, Ostrander, Packer, Pang, Parker, Parker, Pennisi, Rands, Roque, Roque, Salmon Hillbertz, Sargan, Savolainen, Schmutz, Schoenebeck, Seppala, Shannon, Skipper, Stamatoyannopoulos, Stritzel, Sudmant, Sutter, Sutter, Sutter, Tang, Tengvall, Thalmann, Tietz, Tonomura, Vaysse, vonHoldt, Voorbij, Wang, Wang, Wayne, Wilbe, Willet, Wolf, Yokoyama, Yoshida, Yuzbasiyan-Gurkan, Zanna   +97 more
core   +1 more source

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

Veterinary Dermatology, EarlyView.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake, Melissa P. Swan, Kari J. Ekenstedt   +2 more
wiley   +1 more source

Heavy Quark Potential at Finite Temperature in AdS/CFT

, 2009
A calculation of the heavy quark potential at finite temperature at strong coupling based on the AdS/CFT correspondence is presented. The calculation relies on the method of complex string trajectories and on the introduction of a modified ...
Albacete, Albacete, Bak, Brandhuber, Gale, Javier L. Albacete, Laine, Maldacena, Nadkarni, Rey   +9 more
core   +1 more source

Provenance analysis for instagram photos [PDF]

, 2019
As a feasible device fingerprint, sensor pattern noise (SPN) has been proven to be effective in the provenance analysis of digital images. However, with the rise of social media, millions of images are being uploaded to and shared through social media ...
CT Li, CT Li, D Shullani, GJ Bloy, J Lukas, K Dabov, M Chen, R Caldelli, T Gloe, X Kang, X Lin, X Lin, X Lin   +12 more
core   +1 more source

Cleavage and Polyadenylation Specificity Factor Subunit 5 Regulates Pulmonary Artery Smooth Muscle Expansion and Hypoxic Response

MedComm, Volume 7, Issue 2, February 2026.
Increased miR‐3163 targets NUDT21, reducing CPSF5 levels and driving APA dysregulation. This results in 3′UTR shortening of CBFB, which stabilizes RUNX1 and promotes smooth muscle proliferation. PTGER3, is also shortened amplifying hypoxia‐induced RVSP. Together, these pathways contribute to vascular remodeling in PH. Image Created in https://BioRender.
Scott D. Collum, Lisha Zhu, Tingting W. Mills, Rene Girard, Jamie Tran, Tinne C. J. Mertens, Cory Wilson, Nancy Wareing, Erik E. Suarez, Howard J. Huang, Rahat Hussain, Bindu Akkanti, Wenjin J. Zheng, Hari K. Yalamanchili, Bela Patel, Eric J. Wagner, Sandeep Agarwal, Harry Karmouty‐Quintana   +17 more
wiley   +1 more source

Cx40, HAS2 und ADAMTS1

, 2012
Das Endothel, eine einschichtige Zelldecke, ist als innerste Auskleidung von Blutgefäßen direkt dem strömenden Blut ausgesetzt. Sein Funktionszustand wird neben anderen biochemischen und mechanischen Einflüssen durch Wandschubspannung moduliert. Diese ist je nach Lokalisation im Gefäßnetz unterschiedlich: an Prädilektionsstellen für Atherosklerose ...
openaire   +1 more source

Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL

Redox Biology, 2015
The neutral type 2 sphingomyelinase (nSMase2) hydrolyzes sphingomyelin and generates ceramide, a major bioactive sphingolipid mediator, involved in growth arrest and apoptosis.
Sandra Garoby-Salom, Myriam Rouahi, Elodie Mucher, Nathalie Auge, Robert Salvayre, Anne Negre-Salvayre   +5 more
doaj   +1 more source

Oxidized low density lipoprotein (LDL) affects hyaluronan synthesis in human aortic smooth muscle cells [PDF]

, 2013
Thickening of the vessel in response to high low density lipoprotein(s) (LDL) levels is a hallmark of atherosclerosis, characterized by increased hyaluronan (HA) deposition in the neointima.
Bartolini, B., De Luca, G., Deleonibus, S., Hascall, V.C., Karousou, E., Moretto, P., Passi, A., Sawamura, T., Vigetti, D., Viola, M., Wight, T.N.   +10 more
core   +1 more source

Development of a Four‐Language Questionnaire to Investigate Environmental Risk Factors for the Development of Canine Atopic Dermatitis and to Monitor Disease Course and Progression

Veterinary Dermatology, Volume 37, Issue 1, Page 34-44, February 2026.
Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Patricia Clara‐Maria Rhodius, Nina Fischer, Ana Rostaher, Franco Martini, Edwin Chapman, Sabrina Audergon, Stefan Hobi, Georg Lehner, Sylvie Wilhelm, Noëmi van Oordt, Claude Favrot, Malwina Kowalska   +11 more
wiley   +1 more source

Comparison of preoperative NT-proBNP and simple cardiac risk scores for predicting postoperative morbidity after non-cardiac surgery with intermediate or high surgical risk

Perioperative Medicine
Background Chronic heart failure (HF) is frequent in elderly patients undergoing non-cardiac surgery. Preoperative risk stratification is vital and can be achieved using simple clinical risk scores or preoperative N-terminal prohormone of brain ...
Götz Schmidt, Nora Frieling, Emmanuel Schneck, Marit Habicher, Christian Koch, Birgit Aßmus, Michael Sander   +6 more
doaj   +1 more source