Development of a simple procedure for the treatment of femoral head osteonecrosis with intra-osseous injection of bone marrow mesenchymal stromal cells: study of their biodistribution in the early time points after injection [PDF]
, 2015 INTRODUCTION: Osteonecrosis of the femoral head (ONFH) is a degenerative disease progressing to a femoral head (FH) collapse. Injection of osteoprogenitor cells like bone marrow mesenchymal stromal cells (BMSCs) into the FH appears to be a good ...
Alain Rahmouni +10 more
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Biodegradable nanofibers-reinforced microfibrous composite scaffolds for bone tissue engineering [PDF]
, 2010 Native bone extracellular matrix (ECM) is a complex hierarchical fibrous composite structure, resulting from the assembling of collagen fibrils at several length scales, ranging from the macro to the nanoscale.
Correlo, V. M. +6 more
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Ovine mesenchymal stromal cells: morphologic, phenotypic and functional characterization for osteochondral tissue engineering [PDF]
, 2017 [Abstract] Introduction. Knowledge of ovine mesenchymal stromal cells (oMSCs) is currently expanding. Tissue engineering combining scaffolding with oMSCs provides promising therapies for the treatment of osteochondral diseases. Purpose.
Blanco García, Francisco J +7 more
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Journal of Biological EngineeringOsteoporosis is manifested by decreased bone density and deterioration of bone architecture, increasing the risk of bone fractures Human bone marrow mesenchymal stem cells (hBMSCs)-based tissue engineering serves as a crucial technique for regenerating ...
Khadija Akter +3 more
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Stem Cell Research & Therapy, 2019 Background Exosomes are nanoscale membrane vesicles secreted by both normal and cancer cells, and cancer cell-derived exosomes play an important role in the cross-talk between cancer cells and other cellular components in the tumor microenvironment ...
Zhanjun Ma +9 more
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BMC Musculoskeletal DisordersGlucocorticoid-induced osteoporosis (GIOP) is the most common type of secondary osteoporosis. Recently, autophagy has been found to be related with the development of various diseases, including osteoporosis and osteoblast differentiation regulations.
ShuYing Xiao +4 more
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MWCNTs enhance hBMSCs spreading but delay their proliferation in the direction of differentiation acceleration [PDF]
Cell Adhesion & Migration, 2014 Investigating the ability of films of pristine multiwalled nanotubes (MWCNTs) to influence human mesenchymal stem cells' proliferation, morphology, and differentiation into osteoblasts, we concluded to the following: A. MWCNTs delay the proliferation of hBMS cells but increase their differentiation.
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Allogeneic chondrogenically differentiated human bone marrow stromal cells do not induce dendritic cell maturation [PDF]
, 2018 Bone marrow stromal cell (BMSC)-mediated endochondral bone formation may be a promising alternative to the current gold standards of autologous bone transplantation, in the development of novel methods for bone repair.
Brama, P.A.J. (Pieter) +5 more
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ZFP36, an RNA-binding protein promotes hBMSCs osteogenic differentiation via binding with JUN
Journal of Orthopaedic Surgery and ResearchAbstract Osteoporosis (OP) is a metabolic bone disease characterized by progressive decline of bone mass and bone quality, leading to bone fragility and an increased risk of fracture. The osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is crucial to maintain the balance of osteoblast and osteoclast.
Hairong Su +4 more
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BMC CancerBackground The role of miR-145-5p in non-small cell lung cancer (NSCLC) has been studied, however, the regulation of hBMSCs-derived exosomes (Exo) transmitted miR-145-5p in NSCLC was still unknown.
Wu Yan +7 more
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