Results 121 to 130 of about 5,228 (216)
Global effects of RG108 on DNA modifications and DNMTs and TETs enzymatic activities in hBMSCs.
, 2018 hBMSCs were treated with 50 μM RG108 for 3 days and compared to DMEM and DMSO controls. (A) Global methylation was assessed using Imprint Methylated DNA Quantification Kit showing a significant decrease in the RG108 group.
Geórgia da Silva Feltran (4089847) +8 more
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Cb1 Enhanced Osteogenic Differentiation Of Bmscs By Rescue Mitochondrial Metabolism
International Dental JournalAim or purpose: CB1 is the main effector of endogenous cannabinoid system, and our previous study verified CB1 enhanced the osteo/dentinogenic differentiation of dental mesenchymal stem cells (MSCs), which might be a target for alveolar bone regeneration.
Wanhao Yan
doaj +1 more source
Bone potential heterogeneity in hBMSCs is associated with their immunomodulatory capacity
Bone Reports, 2020 Raddi, Najat +8 more
openaire +3 more sources
, 2011 Both ChDPSCs and hBMSCs share identical expression profiles on common cell surface antigens. They were all negative for hematopoietic cell surface markers: CD14, CD34, and CD45; yet identical on cell surface markers shared with BMSCs (CD29, CD44, CD59 ...
Brooke Snyder (47552) +5 more
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International Journal of NanomedicinePeng Luo,1,* Yi Zhang,2,3,* Maodi Huang,1 Guochen Luo,1 Yaping Ma,1,4 Xin Wang1,4 1Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, People’s Republic of China; 2Department of Hygiene ...
Luo P +5 more
doaj
The mineralization effects of Aln on hBMSCs after different treatment strategies.
, 2014 Undifferentiated hBMSCs were treated with 1, 5 or 10 µM Aln during the culture time indicated in Figure 1. The mineralization levels were measured by ARS staining (shown as photographs), which was further quantified (shown as bar).
Che-Yu Hsu (621864) +4 more
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ZFP36, an RNA-binding protein promotes hBMSCs osteogenic differentiation via binding with JUN
Journal of Orthopaedic Surgery and ResearchAbstract Osteoporosis (OP) is a metabolic bone disease characterized by progressive decline of bone mass and bone quality, leading to bone fragility and an increased risk of fracture. The osteogenic differentiation of bone mesenchymal stem cells (BMSCs) is crucial to maintain the balance of osteoblast and osteoclast.
Hairong Su +4 more
openaire +3 more sources
hUCMSCs secretion factors together with hBMSCs promoted ectopic bone formation in nude mice.
, 2015 (A) The sections were stained with H&E and OCN immunostaining. Arrows indicate the areas of osteoid matrices(H&E staining) or OCN positive cells (OCN immunostaining).
Yun-Feng Rui (709357) +8 more
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Effect of High BMI on Human Bone Marrow–Derived Mesenchymal Stromal Cells
Cell TransplantationBone marrow–derived mesenchymal stromal cells (BMSCs) are attractive candidates in tissue engineering and regenerative medicine. Growing evidence has suggested that a high body mass index (BMI) can affect the properties of BMSCs, resulting in a reduced ...
Qiang Zong +3 more
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Journal of Orthopaedic Surgery and ResearchBackground Bone marrow mesenchymal stem cells (BMSCs) exhibit therapeutic potential for osteoporosis through their differentiation into osteoblasts. Here, we investigated the role and mechanism of lymphoid enhancer-binding factor 1 (LEF1) in regulating ...
Zhihong Zhang +5 more
doaj +1 more source