Results 121 to 130 of about 6,219 (219)

In Vitro Evaluation of Proliferation and Migration Behaviour of Human Bone Marrow-Derived Mesenchymal Stem Cells in Presence of Platelet-Rich Plasma

International Journal of Dentistry, 2019
Objective. To access the effects of platelet-rich plasma (PRP) on the behaviour of human bone marrow-derived mesenchymal stem cells (hBMSCs), including proliferation and migration. Methods. PRP was diluted with DMEM/F12, resulting in concentrations of 1%,
Anh Thi Mai Nguyen, Ha Le Bao Tran, Thuy Anh Vu Pham   +2 more
doaj   +1 more source

Cb1 Enhanced Osteogenic Differentiation Of Bmscs By Rescue Mitochondrial Metabolism

International Dental Journal
Aim or purpose: CB1 is the main effector of endogenous cannabinoid system, and our previous study verified CB1 enhanced the osteo/dentinogenic differentiation of dental mesenchymal stem cells (MSCs), which might be a target for alveolar bone regeneration.
Wanhao Yan
doaj   +1 more source

Expression of CD24 in Human Bone Marrow-Derived Mesenchymal Stromal Cells Is Regulated by TGFβ3 and Induces a Myofibroblast-Like Genotype

Stem Cells International, 2016
Human bone marrow-derived stromal cells (hBMSCs) derived from the adult organism hold great promise for diverse settings in regenerative medicine. Therefore a more complete understanding of hBMSC biology to fully exploit the cells’ potential for clinical
Luisa Marilena Schäck, Manuela Buettner, Alexander Wirth, Claudia Neunaber, Christian Krettek, Andrea Hoffmann, Sandra Noack   +6 more
doaj   +1 more source

PCBP2 as an intrinsic aging factor regulates the senescence of hBMSCs through the ROS-FGF2 signaling axis

eLife
Background: It has been reported that loss of PCBP2 led to increased reactive oxygen species (ROS) production and accelerated cell aging. Knockdown of PCBP2 in HCT116 cells leads to significant downregulation of fibroblast growth factor 2 (FGF2).
Pengbo Chen, Bo Li, Zeyu Lu, Qingyin Xu, Huoliang Zheng, Shengdan Jiang, Leisheng Jiang, Xinfeng Zheng   +7 more
doaj   +1 more source

Microdroplets Encapsulated with NFATc1-siRNA and Exosomes-Derived from MSCs Onto 3D Porous PLA Scaffold for Regulating Osteoclastogenesis and Promoting Osteogenesis

International Journal of Nanomedicine
Peng Luo,1,* Yi Zhang,2,3,* Maodi Huang,1 Guochen Luo,1 Yaping Ma,1,4 Xin Wang1,4 1Department of Orthopaedic Surgery, Affiliated Hospital of Zunyi Medical University, Zunyi, Guizhou, 563003, People’s Republic of China; 2Department of Hygiene ...
Luo P, Zhang Y, Huang M, Luo G, Ma Y, Wang X   +5 more
doaj  

hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation

Stem Cell Research & Therapy
Muscle disuse and offloading in microgravity are likely the primary factors mediating spaceflight-induced muscle atrophy, for which there is currently no effective treatment other than exercise. Extracellular vesicles derived from bone marrow mesenchymal stem cells (BMSC-EVs) possess anti-inflammatory and antioxidant properties, offering a potential ...
Mengyuan Chang, Ruiqi Liu, Bingqian Chen, Jin Xu, Wei Wang, Yanan Ji, Zihui Gao, Boya Liu, Xinlei Yao, Hualin Sun, Feng Xu, Yuntian Shen   +11 more
openaire   +3 more sources

Polydeoxyribonucleotide ameliorates IL-1β-induced impairment of chondrogenic differentiation in human bone marrow-derived mesenchymal stem cells

Scientific Reports
Osteoarthritis (OA) is a degenerative disease of the joints, prevalent worldwide. Polydeoxyribonucleotide (PDRN) is used for treating knee OA. However, the role of PDRN in IL-1β-induced inflammatory responses in human bone marrow-derived mesenchymal stem
Ahreum Baek, Dawoon Baek, Sung Hoon Kim, Jinyoung Kim, Geneva Rose Notario, Do‑Won Lee, Hyun Jung Kim, Sung-Rae Cho   +7 more
doaj   +1 more source

Enhanced therapeutic efficacy of repeated bone marrow–derived MSC administration in a murine model of pulmonary fibrosis

Stem Cell Research & Therapy
Background Silicosis is a progressive lung fibrosis lacking effective treatment. Mesenchymal stem cells (MSCs) show antifibrotic potential, but their survival is impaired by the early inflammatory microenvironment.
Zihan Zhou, Jiawei Ding, Shuhua Han, Yuanfang Duan, Jie Chao, Jie Huang   +5 more
doaj   +1 more source

In Vitro Models For Cell-Based Cartilage Regeneration [PDF]

, 2014
__Abstract__ Covering the ends of the long bones in articular joints, cartilage allows smooth, gliding movement of the joints and distributes load evenly across the joint surface.
Vries-Van Melle, M.L. (Marloes) de
core  

Effect of High BMI on Human Bone Marrow–Derived Mesenchymal Stromal Cells

Cell Transplantation
Bone marrow–derived mesenchymal stromal cells (BMSCs) are attractive candidates in tissue engineering and regenerative medicine. Growing evidence has suggested that a high body mass index (BMI) can affect the properties of BMSCs, resulting in a reduced ...
Qiang Zong, Katrin Bundkirchen, Claudia Neunaber, Sandra Noack   +3 more
doaj   +1 more source