Results 101 to 110 of about 6,219 (219)

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, Volume 6, Issue 3, March 2026.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Catechins-Modified Selenium-Doped Hydroxyapatite Nanomaterials for Improved Osteosarcoma Therapy Through Generation of Reactive Oxygen Species [PDF]

, 2019
Osteosarcoma is the most common bone cancer with limited therapeutic options. It can be treated by selenium-doped hydroxyapatite owing to its known antitumor potential. However, a high concentration of Se is toxic toward normal and stem cells whereas its
Hou, Hongwei, Khan, Suliman, Liu, Yang, Siddique, Rabeea, Ullah, Ismat, Ullah, Muhammad Wajid, Xue, Mengzhou, Yang, Guang   +7 more
core   +1 more source

Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs.

Journal of tissue engineering and regenerative medicine, 2013
Heterotypic cell interactions are essential for the homeostasis of bone tissue, in particular the widely studied interaction between osteoblasts and osteoclasts. Closely related with osteoclasts are monocytes/macrophages. These have been shown to produce osteogenic factors, e.g. BMP-2, which plays a key role in bone metabolism.
Pirraco, Rogério P., Reis, R. L., Marques, A. P.   +2 more
openaire   +2 more sources

3D bioprinting in oral and craniomaxillofacial tissue regeneration: Progress, challenges, and future directions

BMEMat, Volume 4, Issue 1, March 2026.
This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan, Haohao Ni, Xingge Yu, Mazaher Gholipourmalekabadi, Tianqi Wang, Kaili Lin, Jinsong Pan, Changyong Yuan   +7 more
wiley   +1 more source

Underlying molecular mechanisms of DIO2 susceptibility in symptomatic osteoarthritis [PDF]

, 2014
Objectives: To investigate how the genetic susceptibility gene DIO2 confers risk to osteoarthritis (OA) onset in humans and to explore whether counteracting the deleterious effect could contribute to novel therapeutic approaches.
Akker, E.B. (Erik) van den, Bomer, N. (Nils), Bos, S.D. (Steffan), Breggen, R. (Ruud) van der, Darvishan, A. (Arash), Duijnisveld, B.J. (Bouke), Eeden, A.E. (Annelies) van, Heijmans, B.T. (Bastiaan), Hollander, W. (Wouter) den, Lakenberg, N. (Nico), Meulenbelt, I. (Ingrid), Nelissen, R.G.H.H. (Rob), Osch, G.J.V.M. (Gerjo) van, Pepers, B.A. (Barry), Ramos, Y.F.M. (Yolande), Roon-Mom, W.M.C. (Willeke) van, Slagboom, P.E. (Eline), Tobi, E.W. (Elmar), Verbeek, F.J. (Fons)   +18 more
core   +1 more source

\u3cem\u3eIn vitro\u3c/em\u3e Effect of Graphene Structures as an Osteoinductive Factor in Bone Tissue Engineering: A Systematic Review [PDF]

, 2018
Graphene and its derivatives have been well‐known as influential factors in differentiating stem/progenitor cells toward the osteoblastic lineage. However, there have been many controversies in the literature regarding the parameters effect on bone ...
Golzar, Hossein, Khojasteh, Arash, Mohammadrezaei, Dorsa, Omidi, Meisam, Rad, Maryam Rezai, Rashedi, Hamid, Tayebi, Lobat, Yazdian, Fatemeh   +7 more
core   +1 more source

Isolation and Characterisation of Mesenchymal Stem Cells

, 2009
MSCs have great therapeutic potential and are currently used in various clinical trials. However, the extremely low frequency of MSCs and the absence of a known cell-specific marker have made their purification and identification a highly challenging ...
Vaghjiani, Rasilaben Jethalal, Vaghjiani, Rasilaben Jethalal   +1 more
core   +1 more source

Chitosan – poly(butylene succinate) scaffolds and human bone marrow stromal cells induce bone repair in a mouse calvaria model [PDF]

, 2012
Tissue engineering sustains the need of a three-dimensional (3D) scaffold to promote the regeneration of tissues in volume. Usually, scaffolds are seeded with an adequate cell population, allowing their growth and maturation upon implantation in vivo ...
Alves da Silva, An, Bianco, Castano-Izquierdo, Correlo, Correlo, Costa-Pinto, Costa-Pinto, Cowan, Delorme, Di Martino, Dégano, Gimble, Gomes, Gupta, Hipp, Hutmacher, Kim, Langer, Malafaya, Mankani, Martins, Martins, Meinel, Montjovent, Oliveira, Salgado, Salgado, Sarugaser, Schmitz, Tuan, Weissman, Wu, Zarzycki   +33 more
core   +1 more source

Cartilage tissue engineering using electrospun PCL nanofiber meshes and MSCs [PDF]

, 2010
Mesenchymal stem cells (MSCs) have been recognized for their ability to differentiate into cells of different tissues such as bone, cartilage, or adipose tissue, and therefore are of great interest for potential therapeutic strategies. Adherent, colony-
Costa, P., Costa-Pinto, A. R., Faria, Susana, Gomes, Manuela E., Martins, A., Neves, N. M., Reis, R. L., Silva, M. L. Alves da   +7 more
core   +1 more source

Human bone marrow mesenchymal stem cells-derived microRNA-205-containing exosomes impede the progression of prostate cancer through suppression of RHPN2

Journal of Experimental & Clinical Cancer Research, 2019
Background Human bone marrow mesenchymal stem cells (hBMSCs) are implicated in cancer initiation and metastasis, sometimes by releasing exosomes that mediate cell communication by delivering microRNAs (miRNAs).
Shuangjian Jiang, Chengqiang Mo, Shengjie Guo, Jintao Zhuang, Bin Huang, Xiaopeng Mao   +5 more
doaj   +1 more source