Results 91 to 100 of about 6,219 (219)
Extracellular vesicles released from periodontal tissues and pathogens mediate local inflammation and disseminate systemically via the circulation. By transporting regulatory microRNAs and inflammatory cytokines, these vesicles link periodontitis to systemic inflammatory conditions and represent emerging targets for minimally invasive diagnostics and ...
Mai Ahmed +3 more
wiley +1 more source
Background/Aims: Bone nonunion remains a challenge for orthopaedists. The technological advancements that have been made in precisely silencing target genes have provided promising methods to address this challenge.
Chuandong Wang +7 more
doaj +1 more source
Isolation and characterization of mesenchymal stem cells from human amniotic membrane [PDF]
[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy.
Blanco García, Francisco J +6 more
core +2 more sources
Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation
ABSTRACT Large‐area bone loss from disease, trauma, or congenital defects requires surgical procedures and bone grafting. Alveolar bone loss from severe periodontal disease and non‐unions often demands immediate grafting. Treating large alveolar bone defects using grafts and substitutes is challenging due to the complex oral environment, infection ...
Allen Zennifer +5 more
wiley +1 more source
c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. [PDF]
ObjectiveADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix.
Amanatullah, Derek F +4 more
core +2 more sources
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi +8 more
wiley +1 more source
External loading determines specific ECM genes regulation [PDF]
Bio artificial matrices embedded with cells are simulated in bioreactors to facilitate ECM production. As cells attach, they develop forces, which are dependent on cell type and matrix stiffness.
Brown, R +3 more
core
Effects of high glucose on osteogenic differentiation of hBMSC
Objective To investigate the effects of different glucose concentration on the proliferation and osteogen⁃ ic differentiation of human bone marrow mesenchymal stem cells (hBMSC) in vivo. Methods Cultured with basal medi⁃ um containing different glucose concentrations, CCK⁃8 cell proliferation was detected at 1, 4, 7, 10 days.
GAO Hai +4 more
openaire +1 more source
ABSTRACT Osteosarcoma (OS) is an aggressive primary bone tumour with high metastatic potential. Current treatments including surgery and chemotherapy are limited by side effects and chemoresistance, underscoring the need for novel therapies. This study aimed to investigate the antitumor potential of resveratrol (RSV), a natural polyphenol, as a novel ...
Raffaella De Pace +6 more
wiley +1 more source
Human Mesenchymal Stromal Cells Decrease Mortality Following Intestinal Ischemia and Reperfusion Injury [PDF]
Background Cellular therapy is a novel treatment option for intestinal ischemia. Bone marrow–derived mesenchymal stromal cells (BMSCs) have previously been shown to abate the damage caused by intestinal ischemia/reperfusion (I/R) injury.
Amanda R. Jensen +4 more
core +1 more source

