Results 91 to 100 of about 6,219 (219)

Periodontitis and extracellular vesicles: Emerging roles in inflammation, tissue destruction and systemic crosstalk

open access: yesClinical and Translational Discovery, Volume 6, Issue 2, April 2026.
Extracellular vesicles released from periodontal tissues and pathogens mediate local inflammation and disseminate systemically via the circulation. By transporting regulatory microRNAs and inflammatory cytokines, these vesicles link periodontitis to systemic inflammatory conditions and represent emerging targets for minimally invasive diagnostics and ...
Mai Ahmed   +3 more
wiley   +1 more source

Improving Bone Regeneration Using Chordin siRNA Delivered by pH-Responsive and Non-Toxic Polyspermine Imidazole-4,5-Imine

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Bone nonunion remains a challenge for orthopaedists. The technological advancements that have been made in precisely silencing target genes have provided promising methods to address this challenge.
Chuandong Wang   +7 more
doaj   +1 more source

Isolation and characterization of mesenchymal stem cells from human amniotic membrane [PDF]

open access: yes, 2011
[Abstract] Introduction: The human amniotic membrane is a highly abundant and readily available tissue that may be useful for regenerative medicine and cell therapy.
Blanco García, Francisco J   +6 more
core   +2 more sources

Alveolar Bone Regeneration: Smart Biomaterials and Physical Stimulation

open access: yesJournal of Biomedical Materials Research Part B: Applied Biomaterials, Volume 114, Issue 4, April 2026.
ABSTRACT Large‐area bone loss from disease, trauma, or congenital defects requires surgical procedures and bone grafting. Alveolar bone loss from severe periodontal disease and non‐unions often demands immediate grafting. Treating large alveolar bone defects using grafts and substitutes is challenging due to the complex oral environment, infection ...
Allen Zennifer   +5 more
wiley   +1 more source

c-Maf Transcription Factor Regulates ADAMTS-12 Expression in Human Chondrogenic Cells. [PDF]

open access: yes, 2013
ObjectiveADAMTS (a disintegrin and metalloproteinase with thrombospondin type-1 motif) zinc metalloproteinases are important during the synthesis and breakdown of cartilage extracellular matrix.
Amanatullah, Derek F   +4 more
core   +2 more sources

Targeting Ferroptosis With Natural Products for the Treatment of Skeletal System Disease: An Updated Review

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Skeletal system diseases, encompassing chronic disorders of the skeletal system which commonly include osteoarthritis, rheumatoid arthritis, osteoporosis and osteosarcoma. Their incidence rates have been increasing in recent years, resulting in significant social and economic burdens.
Qian Yi   +8 more
wiley   +1 more source

External loading determines specific ECM genes regulation [PDF]

open access: yes, 2006
Bio artificial matrices embedded with cells are simulated in bioreactors to facilitate ECM production. As cells attach, they develop forces, which are dependent on cell type and matrix stiffness.
Brown, R   +3 more
core  

Effects of high glucose on osteogenic differentiation of hBMSC

open access: yes口腔疾病防治, 2017
Objective To investigate the effects of different glucose concentration on the proliferation and osteogen⁃ ic differentiation of human bone marrow mesenchymal stem cells (hBMSC) in vivo. Methods Cultured with basal medi⁃ um containing different glucose concentrations, CCK⁃8 cell proliferation was detected at 1, 4, 7, 10 days.
GAO Hai   +4 more
openaire   +1 more source

Gene Expression Alterations Associated With Resveratrol‐Induced Antiproliferative Effects and S‐Phase Cell Cycle Arrest in Osteosarcoma Cancer Cells

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 7, April 2026.
ABSTRACT Osteosarcoma (OS) is an aggressive primary bone tumour with high metastatic potential. Current treatments including surgery and chemotherapy are limited by side effects and chemoresistance, underscoring the need for novel therapies. This study aimed to investigate the antitumor potential of resveratrol (RSV), a natural polyphenol, as a novel ...
Raffaella De Pace   +6 more
wiley   +1 more source

Human Mesenchymal Stromal Cells Decrease Mortality Following Intestinal Ischemia and Reperfusion Injury [PDF]

open access: yes, 2015
Background Cellular therapy is a novel treatment option for intestinal ischemia. Bone marrow–derived mesenchymal stromal cells (BMSCs) have previously been shown to abate the damage caused by intestinal ischemia/reperfusion (I/R) injury.
Amanda R. Jensen   +4 more
core   +1 more source

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