Results 71 to 80 of about 5,228 (216)

YTHDF3 Enhances Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells in Osteoporosis by Promoting TBX19 Expression

open access: yesCell Proliferation, EarlyView.
In this study, OP‐BMSCs were successfully isolated from OVX osteoporotic rats. Mechanistic investigations revealed that the RNA‐binding protein YTHDF3 significantly upregulates Tbx19 expression by enhancing the stability of Tbx19 mRNA. Elevated Tbx19 levels, in turn, activate key osteogenic molecules, effectively promoting the differentiation of OP ...
Qianke Tao   +9 more
wiley   +1 more source

miR-346 promotes osteogenic differentiation of hBMSCs.

open access: yes, 2013
(A) qRT-PCR analysis of miR-346 in hBMSCs infected by miR-346-lentivirus or transfected with anti-miR346. The data were normalized to U6. (B) qRT-PCR analysis of the osteoblastic marker genes RUNX2, ALP, and OPN at day 15 of osteoblast differentiation ...
Qing Wang (27728)   +3 more
core   +1 more source

LncRNA USP2-AS1 facilitates the osteogenic differentiation of bone marrow mesenchymal stem cells by targeting KDM3A/ETS1/USP2 to activate the Wnt/β-catenin signaling pathway

open access: yesRNA Biology
Human bone marrow mesenchymal stem cells (HBMSCs) can promote new bone formation. Previous studies have proven the ability of long non-coding RNAs (lncRNAs) to modulate the osteogenic differentiation of mesenchymal stem cells.
Wanxin Luo   +6 more
doaj   +1 more source

Osteomyelitis: Epidemiology, Classification, Pathophysiology, Clinical Features, Diagnosis, and Management

open access: yesMedComm, Volume 7, Issue 10, October 2026.
The immunosuppressive in OM Staphylococcus aureus employs multiple physical barriers to evade host immunity during skeletal infection, including biofilm formation on implant surfaces and necrotic bone tissues, invasion into the osteocyte lacuno‐canalicular network (OLCN), intracellular persistence within osteoblasts, osteoclasts, and osteocytes, and ...
Qingqiang Lei   +7 more
wiley   +1 more source

Effect of RG108 on hBMSCs cell viability.

open access: yes, 2018
(A, B) 2 populations of hBMSCs were treated with 400 μM, 800 μM and 1.6 mM of RG108 for 7 days, showing significant reduction in viability comparing to DMEM and DMSO control groups.
Geórgia da Silva Feltran (4089847)   +8 more
core   +1 more source

High throughput GeneChip analysis of GsαR201C hBMSCs.

open access: yes, 2020
(A) Western blotting on hBMSCs from three different individuals (D01, D02, D03), transduced with LV-Ctr (C), LV- GsαR201C (R) showing the expression of the exogenously provided mutant GsαR201C as highlighted by immunoblotting with anti-HA and anti-Gsα ...
Letizia Astrologo (438190)   +13 more
core   +1 more source

Extrusion Bioprinting for Wound Healing: Innovations in Functionalized Bioinks and Bioprinting Technology

open access: yesAdvanced Materials Technologies, Volume 11, Issue 18, 18 September 2026.
Extrusion‐based bioprinting (EBB) has emerged as a versatile biofabrication platform capable of precisely depositing bioinks composed of biomaterials, cells, and bioactive agents to generate patient‐specific, biomimetic skin constructs. This paper presents a state‐of‐the‐art and forward‐looking overview of EBB for wound healing, encompassing printing ...
Hien‐Phuong Le   +4 more
wiley   +1 more source

Calreticulin expression in DIO2 overexpressing hBMSCs.

open access: yes, 2016
qPCR expression of Calr in hBMSCs transduced with either a control virus-vector (eGFP) or a DIO2-eGFP vector. Values of the RT-qPCR are displayed as the average±SEM, normalized for GAPDH expression and relative to the control sample at every timepoint ...
Rik J. U. Lories (2741824)   +9 more
core   +1 more source

Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs.

open access: yesJournal of tissue engineering and regenerative medicine, 2013
Heterotypic cell interactions are essential for the homeostasis of bone tissue, in particular the widely studied interaction between osteoblasts and osteoclasts. Closely related with osteoclasts are monocytes/macrophages. These have been shown to produce osteogenic factors, e.g. BMP-2, which plays a key role in bone metabolism.
Pirraco, Rogério P.   +2 more
openaire   +2 more sources

Dynamic Tracking Human Mesenchymal Stem Cells Tropism following Smoke Inhalation Injury in NOD/SCID Mice

open access: yesStem Cells International, 2016
Multiple preclinical evidences have supported the potential value of mesenchymal stem cells (MSCs) for treatment of acute lung injury (ALI). However, few studies focus on the dynamic tropism of MSCs in animals with acute lung injury.
MeiJuan Song   +14 more
doaj   +1 more source

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