Results 71 to 80 of about 3,978 (176)

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, Volume 36, Issue 40, 18 May 2026.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Engineering Extracellular Vesicle Production Through Magnetic Ion Channel Activation for Bone Regeneration

Advanced Healthcare Materials, Volume 15, Issue 18, 15 May 2026.
Magnetic Ion Channel Activation (MICA) enables remote stimulation of mechanosensitive ion channels using functionalised magnetic nanoparticles, enhancing extracellular vesicle (EV) biogenesis is pre‐osteoblasts. MICA desrived EVs exhibit typical nano‐vesicular characteristics but display superior pro‐osteogeneic activity, promoting mesenchymal stem ...
Afeesh Rajan Unnithan, Kenny Man, Kritika, Lee A. Gethings, Christopher J. Hughes, Alicia Keenan, Liam Heaney, Sophie C. Cox, Owen G. Davies, Alicia J. El Haj   +9 more
wiley   +1 more source

CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment

International Journal of Molecular Sciences, 2020
Near the bone remodeling compartments (BRC), extracellular calcium concentration (Ca2+o) is locally elevated and bone marrow stromal cells (BMSCs) close to the BRC can be exposed to high calcium concentration. The calcium-sensing receptor (CaSR) is known to play a key role in maintaining extracellular calcium homeostasis by sensing fluctuations in the ...
Hyunji Cho, Jisoo Lee, Seoyoung Jang, Jungsun Lee, Tong In Oh, Youngsook Son, EunAh Lee   +6 more
openaire   +2 more sources

Nanoclay‐Engineered Scaffolds for the Controlled Delivery of Biomolecules in Regenerative Medicine

Asia-Pacific Journal of Chemical Engineering, Volume 21, Issue 3, May/June 2026.
ABSTRACT Regenerative medicine combines biomaterials, cells, scaffolds, and bioactive agents via modern technologies to aid in the reconstruction and repair of damaged tissues. Among these, nanoclay scaffolds have demonstrated unique advantages in facilitating the delivery of therapeutic agents.
Mehri Shadi, Saeed Vafaei‐Nezhad, Ahmad Gholamalizadeh Ahangar   +2 more
wiley   +1 more source

Engineering Biofunctional Tantalum Implants Through Surface Functionalization for Infection‐Resistant Bone Regeneration

Small Structures, Volume 7, Issue 5, May 2026.
This comprehensive review provides an overview of tantalum surface modification strategies, their impact on biocompatibility and osteointegration, and emerging advances shaping next‐generation orthopedic implant performance. Tantalum has emerged as a promising metallic biomaterial for orthopedic implants owing to its excellent biocompatibility ...
Zhenyu Yang, Yu Hong, Jiangqi Zhu, Zhongheng Wu, Wenhua Huang, Weihu Yang, Xingchen Yan, Huan Liu   +7 more
wiley   +1 more source

Influence of scaffold composition over in vitro osteogenic differentiation of hBMSCs and in vivo inflammatory response

Journal of Biomaterials Applications, 2013
To understand the role of chitosan in chitosan-poly(butylene succinate) scaffolds (50% wt), 50%, 25%, and 0% of chitosan were used to produce different scaffolds. These scaffolds were in vitro seeded and cultured with human bone marrow stromal cells in osteogenic conditions, revealing that higher percentage of chitosan showed enhanced cell viability ...
Pinto, A. R., Vargel, I., Tuzlakoglu, K., Correlo, V. M., Sol, P. C., Faria, Susana, Piskin, Erhan, Reis, R. L., Neves, N. M.   +8 more
openaire   +3 more sources

Human bone marrow mesenchymal stem cells-derived microRNA-205-containing exosomes impede the progression of prostate cancer through suppression of RHPN2

Journal of Experimental & Clinical Cancer Research, 2019
Background Human bone marrow mesenchymal stem cells (hBMSCs) are implicated in cancer initiation and metastasis, sometimes by releasing exosomes that mediate cell communication by delivering microRNAs (miRNAs).
Shuangjian Jiang, Chengqiang Mo, Shengjie Guo, Jintao Zhuang, Bin Huang, Xiaopeng Mao   +5 more
doaj   +1 more source

Nonthermal biocompatible plasma in stimulating osteogenic differentiation by targeting p38/ FOXO1 and PI3K/AKT pathways in hBMSCs

Journal of Biological Engineering
Osteoporosis is manifested by decreased bone density and deterioration of bone architecture, increasing the risk of bone fractures Human bone marrow mesenchymal stem cells (hBMSCs)-based tissue engineering serves as a crucial technique for regenerating ...
Khadija Akter, Youngsun Kim, Eun Ha Choi, Ihn Han   +3 more
doaj   +1 more source

Bone marrow mesenchymal stem cells-derived exosomal miR-145-5p reduced non-small cell lung cancer cell progression by targeting SOX9

BMC Cancer
Background The role of miR-145-5p in non-small cell lung cancer (NSCLC) has been studied, however, the regulation of hBMSCs-derived exosomes (Exo) transmitted miR-145-5p in NSCLC was still unknown.
Wu Yan, Haiyu Yang, Dekun Duan, Yufeng Wu, Youhu Liu, Jianping Mao, Yong Zhao, Junsong Ye   +7 more
doaj   +1 more source

In Vitro Evaluation of Proliferation and Migration Behaviour of Human Bone Marrow-Derived Mesenchymal Stem Cells in Presence of Platelet-Rich Plasma

International Journal of Dentistry, 2019
Objective. To access the effects of platelet-rich plasma (PRP) on the behaviour of human bone marrow-derived mesenchymal stem cells (hBMSCs), including proliferation and migration. Methods. PRP was diluted with DMEM/F12, resulting in concentrations of 1%,
Anh Thi Mai Nguyen, Ha Le Bao Tran, Thuy Anh Vu Pham   +2 more
doaj   +1 more source