Results 51 to 60 of about 6,219 (219)

Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway

Clinical Interventions in Aging, 2022
Bo Wang,1,* Song Gong,2,* Lizhi Han,2 Wenkai Shao,2 Zilin Li,2 Jiawei Xu,2 Xiao Lv,2 Baojun Xiao,2 Yong Feng2 1Department of Rehabilitation, Wuhan No.1 Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022,
Wang B, Gong S, Han L, Shao W, Li Z, Xu J, Lv X, Xiao B, Feng Y   +8 more
doaj  

MicroRNA-21 promotes head and neck squamous cell carcinoma (HNSCC) induced transition of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

BMC Cancer, 2023
Background Most patients diagnosed with head and neck tumor will present with locally advanced disease, requiring multimodality therapy. Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-derived signals, such as ...
Hao Wang, Zhengyu Zhou, Wenchao Lin, Yechun Qian, Shifang He, Jun Wang   +5 more
doaj   +1 more source

Osteogenic differentiation of human bone marrow mesenchymal stem cells seeded on melt based chitosan scaffolds for bone tissue engineering applications [PDF]

, 2009
The purpose of this study was to evaluate the growth patterns and osteogenic differentiation of human bone marrow mesenchymal stem cells (hBMSCs) when seeded onto new biodegradable chitosan/polyester scaffolds.
Bhattacharya, Mrinal, Charbord, Pierre, Correlo, V. M., Delorme, B., Neves, N. M., Pinto, A. R., Reis, R. L., Sol, Paula C.   +7 more
core   +1 more source

3D (Bio) Printing Combined Fiber Fabrication Methods for Tissue Engineering Applications: Possibilities and Limitations

Advanced Functional Materials, EarlyView.
Biofabrication aims at providing innovative technologies and tools for the fabrication of tissue‐like constructs for tissue engineering and regenerative medicine applications. By integrating multiple biofabrication technologies, such as 3D (bio) printing with fiber fabrication methods, it would be more realistic to reconstruct native tissue's ...
Waseem Kitana, Indra Apsite, Leonid Ionov   +2 more
wiley   +1 more source

Human Bone Marrow Stromal Cells can Differentiate to a Retinal Pigment Epithelial Phenotype when Co-Cultured with Pig Retinal Pigment Epithelium using a Transwell System

Cellular Physiology and Biochemistry, 2013
Background: There is an increasing interest in generating retinal pigment epithelial (RPE) cells from stem cells for therapy against degenerative eye diseases.
Ping Duan, Haiwei Xu, Yuxiao Zeng, Yi Wang, Zheng Qin Yin   +4 more
doaj   +1 more source

Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway

Biology Direct, 2023
The human bone marrow mesenchymal stem cells (hBMSCs) undergo intense osteogenic differentiation, a crucial bone formation mechanism. Evidence from prior studies suggested an association between long noncoding RNAs (lncRNAs) and the osteogenic ...
Zhaoyi Mai, Jingpeng Liu, Xiao Jiang, Wenli Gu, Wei Wang, Simin Li, Gerhard Schmalz, Hui Xiao, Jianjiang Zhao   +8 more
doaj   +1 more source

DPA promotes hBMSCs osteogenic differentiation by miR-9-5p/ERK/ALP signaling pathway

International Journal of Medical Sciences, 2022
Docosahexaenoic acid (DHA) has been reported potentiate osteogenic differentiation, while Docosapentaenoic acid (DPA), another Omega-3 fatty acid, its contribution to the osteogenic differentiation of human bone-marrow-derived mesenchymal stromal cells (hBMSCs) is not entirely elucidated.
Gao, Xiang, Hong, Guanhao, Zhan, Weiqiang, Liu, Tianfeng, Yan, Shouquan, Deng, Mingzhu, Tu, Chenlin, Li, Peng   +7 more
openaire   +2 more sources

Aqueous Two‐Phase Bioinks for Discrete Packing and Compartmentalization of 3D Bioprinted Cells

Advanced Healthcare Materials, EarlyView.
Aqueous two‐phase systems (ATPS) enable the formation of biomimetic interfaces crucial for tissue engineering. However, clinical translation remains limited by the challenge of precisely controlling cellular compartmentalization. Here, we developed ATPS biomaterial inks for 3D bioprinting allowing tuneable droplet formation via NaCl modulation.
Martina Marcotulli, Arianna Iacomino, Federico Serpe, Lucia Iafrate, Marco Bastioli, Giorgia Montalbano, Biagio Palmisano, Silvia Franco, Roberta Angelini, Alessandro Corsi, Mara Riminucci, Giancarlo Ruocco, Chiara Scognamiglio, Andrea Barbetta, Gianluca Cidonio   +14 more
wiley   +1 more source

Metabolism of polyunsaturated fatty acids in human bone marrow derived mesenchymal stromal cells [PDF]

, 2017
The application of human bone marrow derived mesenchymal stromal cells (hBMSCs) for regenerative or immunomodulatory therapies, e.g. treatment of the graft-versus-host disease, requires in vitro expansion of the cells.
Tigistu-Sahle, Feven
core  

Production and Characterization of a Novel, Electrospun, Tri-Layer Polycaprolactone Membrane for the Segregated Co-Culture of Bone and Soft Tissue [PDF]

, 2016
Composite tissue-engineered constructs combining bone and soft tissue have applications in regenerative medicine, particularly dentistry. This study generated a tri-layer, electrospun, poly-ε-caprolactone membrane, with two microfiber layers separated by
Delaine-Smith, Delaine-Smith, Frazer Bye, Gwendolen Reilly, Moira Ireland, Nicola Green, Sasima Puwanun, Sheila MacNeil, Sittichokechaiwut   +8 more
core   +2 more sources