Results 51 to 60 of about 5,228 (216)

Identification of a clinical signature predictive of differentiation fate of human bone marrow stromal cells

Stem Cell Research & Therapy, 2021
Background Transplantation of human bone marrow stromal cells (hBMSCs) is a promising therapy for bone regeneration due to their ability to differentiate into bone forming osteoblastic cells.
Justyna Magdalena Kowal, Sören Möller, Dalia Ali, Florence Figeac, Torben Barington, Hagen Schmal, Moustapha Kassem   +6 more
doaj   +1 more source

Integrating chemo‐mechanical cues in nano‐microscale environments for stem cell regulation

BMEMat, EarlyView.
Nano/microscale control strategies, including nano/microscale materials, ligand spacings, and cell encapsulating gels, cell mechanics, integrin signaling, and biochemical cues to direct stem cell fate, tissue regeneration, and organoid engineering, enabling advanced biomedical applications through mechanoregulation at cell‐material interfaces ...
Rajendra K. Singh, Varsha Sagar, Amal George Kurian, Shreyas Kumar Jain, Hye Sung Kim, Hae‐Won Kim   +5 more
wiley   +1 more source

Effect of Adv-hVEGF-hIL-1Ra transduced hBMSCs on the outcome of human islet transplantation.

, 2013
(A, B, C) The blood glucose level of every mouse after receiving 2000 human islet equivalent transplanted either alone or hBMSCs before or after transduction with Adv-hVEGF-hIL-1Ra (A–C). (D) Diabetes reversal ratio of the diabetic mice after human islet
Ram I. Mahato (317727), Vaibhav Mundra (477805), Hao Wu (65943)   +2 more
core   +1 more source

MWCNTs enhance hBMSCs spreading but delay their proliferation in the direction of differentiation acceleration [PDF]

Cell Adhesion & Migration, 2014
Investigating the ability of films of pristine multiwalled nanotubes (MWCNTs) to influence human mesenchymal stem cells' proliferation, morphology, and differentiation into osteoblasts, we concluded to the following: A. MWCNTs delay the proliferation of hBMS cells but increase their differentiation.
openaire   +2 more sources

Micro-/nano-structured zirconia surface promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by reducing pyroptosis under inflammatory conditions

Journal of Dental Sciences
Background/purpose: Promoting osteogenesis under inflammatory conditions holds promise for preventing and mitigating peri-implantitis. Cell pyroptosis inhibits osteoblast-mediated bone formation.
Hui-Min Wang, Qian Ding, Ying Chen, Yao-Jun Zhang, Zhi-Xiao Wu, Xiao Zhang, Lei Zhang   +6 more
doaj   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

hUCMSCs secretion factors promote mineralization in osteogenic differentiation of hBMSCs.

, 2015
(A) hBMSCs were treated with hUCMSCs secretion factors (from 0.01 μg/ml to 20 μg/ml) for 3 days or 5 days. MTT assay was performed to test the cell proliferation rate. DMSO served as control.
Yun-Feng Rui (709357), Ying-Hui Li (315831), Wayne Yuk-Wai Lee (709360), Shuo Huang (624671), Si-En Lin (709358), Gang Li (34549), Kui-Xing Wang (709355), Liang-Liang Xu (709356), Jiang-Hui Xiong (709359)   +8 more
core   +1 more source

hBMSCs and FD-related processes.

, 2020
(A) Cartoon depicting the in cis differentiation properties of BMSCs into osteoblasts and adipocytes, along with the in trans effects of BMSCs on hematopoiesis, osteoclastogenesis and vascularity (ad, adipocyte; ob osteoblast, oc osteoclast.
Letizia Astrologo (438190), Fiammetta Vernì (271646), Agnese Persichetti (411111), Simona Del Giudice (6013160), Giuseppe Giannicola (8378475), Enrico Tagliafico (438193), Romina Burla (760345), Isabella Saggio (112602), Mara Riminucci (6740549), Cristina Remoli (8378472), Alessandro Corsi (4180756), Pamela G. Robey (8354283), Domenico Raimondo (760344), Mattia La Torre (760451)   +13 more
core   +1 more source

LncRNA MEG3 promotes osteogenesis of hBMSCs by regulating miR-21-5p / SOD3 axis

Acta Biochimica Polonica, 2022
Background: This study aimed to investigate the role of long non-coding (Lnc) RNA MEG3 on the osteogenesis of human bone marrow mesenchymal stem cells (hBMSCs). Materials and Methods: The binding of miR-21-5p to LncRNA MEG3 and SOD3 was determined using luciferase reporter assay; fluorescence quantitative PCR was used to detect the expression of LncRNA
Shuangli, Wang, Gaoxin, Xiong, Rende, Ning, Zhengjun, Pan, Meihua, Xu, Zhengang, Zha, Ning, Liu   +6 more
openaire   +3 more sources

Effects of miR-103 by negatively regulating SATB2 on proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells.

PLoS ONE, 2020
BACKGROUND:The proliferation and osteogenic differentiation of human bone marrow mesenchymal stem cells (HBMScs) are modulated by a variety of microRNAs (miRNAs). SATB homeobox 2 (SATB2) is a critical transcription factor that contributes to maintain the
Hao Lv, Huashan Yang, Yuanrui Wang
doaj   +1 more source