Results 61 to 70 of about 5,228 (216)

Hierarchically Rough rGO/HAp Nanocoatings on SLM Ti–6Al–4 V Implants for Enhanced Biointegration

open access: yesSmall, EarlyView.
This study investigates HAp/rGO bioactive coatings on Ti‐6Al‐4V fixation implants fabricated by selective laser melting with systematically varied volumetric energy density to tailor the as‐built surface state. Composite coatings were deposited by electrophoretic deposition and characterized using micro‐CT, profilometry, FESEM/EDS, and detailed XPS to ...
Muhammad Usama Zaheer   +9 more
wiley   +1 more source

Engraftment of hBMSCs-VEGF in the injured pancreas.

open access: yes, 2013
Immunofluorescence staining for human β-2-microglobulin (green) shows successful engraftment of hBMSCs-VEGF in the pancreas of rescued mice (A). Panel B shows higher magnification of inset in panel A indicating differentiation of human cells to vascular ...
Jang-Won Lee (312197)   +7 more
core   +1 more source

[Retracted] TRPM7 Upregulate the Activity of SMAD1 through PLC Signaling Way to Promote Osteogenesis of hBMSCs [PDF]

open access: yesBioMed Research International, 2020
TRPM7 is a member of the transient receptor potential cation channel (TRP channel) subfamily M and possesses both an ion channel domain and a functional serine/threonine α‐kinase domain. It has been proven to play an essential role in the osteogenic differentiation of human bone marrow‐derived mesenchymal stem cells (hBMSCs).
Fanfan Hong   +6 more
openaire   +2 more sources

Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway

open access: yesBiology Direct, 2023
The human bone marrow mesenchymal stem cells (hBMSCs) undergo intense osteogenic differentiation, a crucial bone formation mechanism. Evidence from prior studies suggested an association between long noncoding RNAs (lncRNAs) and the osteogenic ...
Zhaoyi Mai   +8 more
doaj   +1 more source

Progress in bone tissue engineering biomaterials: Development, challenges, and prospects

open access: yesVIEW, EarlyView.
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang   +7 more
wiley   +1 more source

Multilineage potential of hBMSCs after incubation with the complexes.

open access: yes, 2013
a) unstained osteoblasts, b) stained osteoblasts, c) unstained adipocytes, d) stained adipocytes. After incubation with complexes formed at an N/P ratio of 20 for 12 h, the hBMSCs were successfully induced to differentiate into osteoblasts (a and b) and ...
Zaibo Jiang (467729)   +8 more
core   +1 more source

Knockdown of HDAC9 Inhibits Osteogenic Differentiation of Human Bone Marrow Mesenchymal Stem Cells Partially by Suppressing the MAPK Signaling Pathway

open access: yesClinical Interventions in Aging, 2022
Bo Wang,1,* Song Gong,2,* Lizhi Han,2 Wenkai Shao,2 Zilin Li,2 Jiawei Xu,2 Xiao Lv,2 Baojun Xiao,2 Yong Feng2 1Department of Rehabilitation, Wuhan No.1 Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022,
Wang B   +8 more
doaj  

LINC00473 regulated apoptosis, proliferation and migration but could not reverse cell cycle arrest of human bone marrow mesenchymal stem cells induced by a high-dosage of dexamethasone

open access: yesStem Cell Research, 2020
Dysfunction of bone marrow mesenchymal stem cells (BMSCs) is involved in the pathogenesis of steroid-induced osteonecrosis of the femoral head (SONFH).
Yingxing Xu   +6 more
doaj   +1 more source

Extracellular vesicles in pharmacology: Innovations in drug delivery and therapeutic applications in cancer

open access: yesBritish Journal of Pharmacology, EarlyView.
Extracellular vesicles (EVs) are a diverse population of membrane nanoparticles secreted by nearly all cell types, playing a key role in intercellular communication by transferring bioactive macromolecular cargo. In cancer, EVs shape both the local tumour microenvironment and distant premetastatic niches.
Evangelia Pantazaka   +3 more
wiley   +1 more source

Chordin-Like 1 Improves Osteogenesis of Bone Marrow Mesenchymal Stem Cells Through Enhancing BMP4-SMAD Pathway

open access: yesFrontiers in Endocrinology, 2019
Chordin-like 1 (CHRDL1) is a secreted glycoprotein with repeated cysteine-rich domains, which can bind to BMPs family ligands. Although it has been reported to play important roles in several systems, the exact roles of CHRDL1 on human bone mesenchymal ...
Tao Liu   +9 more
doaj   +1 more source

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