Accelerated Bone Regeneration by Two-Photon Photoactivated Carbon Nitride Nanosheets [PDF]
Human bone marrow-derived mesenchymal stem cells (hBMSCs) present promising opportunities for therapeutic medicine. Carbon derivatives showed only marginal enhancement in stem cell differentiation toward bone formation.
Ahmad M. Harzandi +12 more
core +2 more sources
Inhibiting KCNMA1-AS1 promotes osteogenic differentiation of HBMSCs via miR-1303/cochlin axis
Abstract Objective Osteoporosis is a progressive systemic skeletal disorder. Multiple profiling studies have contributed to characterizing biomarkers and therapeutic targets for osteoporosis. However, due to the limitation of the platform of miRNA sequencing, only a part of miRNA can be sequenced based on one platform.
Yuan Lin +5 more
openaire +3 more sources
miR-215-5p regulates osteoporosis development and osteogenic differentiation by targeting XIAP
Background Osteoporosis (OP) is a metabolic disease that involves microstructure destruction and fracture damage. The present study probed into the significance of miR-215-5p in OP progression.
Zilong Yin +5 more
doaj +1 more source
Comparison of hIGF-1 Gene Transfection to the hBMSCs and Human Meniscal Fibrochondrocytes [PDF]
Treatment strategies for meniscal injury are shifting from meniscectomy to repair, especially cell-based therapy. Delivering selected genes to donor cells can modify differentiation and proliferation. Efficiency of gene transfection and expression may relate to cell type.Full-length hIGF-1 cDNA was cloned into eukaryotic expression vector by PCR. Human
Zhang, Haining +3 more
openaire +2 more sources
The influence of patterned nanofiber meshes on human mesenchymal stem cell osteogenesis [PDF]
A specially designed electroconductive collector enables the electrospinning of P-NFM composed of areas of parallel/uniaxially aligned fibers and areas of random/orthogonal nanofiber distribution.
Faria, Susana +5 more
core +1 more source
Perivascular-like cells contribute to the stability of the vascular network of osteogenic tissue formed from cell sheet-based constructs [PDF]
In recent years several studies have been supporting the existence of a close relationship in terms of function and progeny between Mesenchymal Stem Cells (MSCs) and Pericytes.
A Armulik +82 more
core +3 more sources
A simple rocker-induced mechanical stimulus upregulates mineralization by human osteoprogenitor cells in fibrous scaffolds [PDF]
Biodegradable electrospun polycaprolactone scaffolds can be used to support bone-forming cells and could fill a thin bony defect, such as in cleft palate.
Colley, H.E. +5 more
core +2 more sources
Stro-1 has proved an efficacious marker for enrichment of skeletal stem and progenitor cells although isolated populations remain heterogeneous, exhibiting variable colony-forming efficiency and osteogenic differentiation potential. The emerging findings
Gothard, David +3 more
core +2 more sources
The use of umbilical stem cells [PDF]
The use of umbilical stem cells in tissue engineering is gaining in popularity. Some of the various uses of these umbilical stem cells are highlighted in this review, focusing mainly on their cartilage, bone and neuronal differentiating abilities.
Blundell, Renald, Cassar, Peter
core +1 more source
Bone tissue engineering usually consists of associating osteoprogenitor cells and macroporous scaffolds. This study investigated the in vitro osteoblastic differentiation and resulting in vivo bone formation induced by a different approach that uses particles as substrate for human bone marrow stromal cells (hBMSCs), in order to provide cells with a ...
Cordonnier, Thomas +7 more
openaire +3 more sources

