Results 41 to 50 of about 5,228 (216)

MicroRNA-21 promotes head and neck squamous cell carcinoma (HNSCC) induced transition of bone marrow mesenchymal stem cells to cancer-associated fibroblasts

BMC Cancer, 2023
Background Most patients diagnosed with head and neck tumor will present with locally advanced disease, requiring multimodality therapy. Bone marrow-derived mesenchymal stromal cells (BMSCs) respond to a variety of tumor cell-derived signals, such as ...
Hao Wang, Zhengyu Zhou, Wenchao Lin, Yechun Qian, Shifang He, Jun Wang   +5 more
doaj   +1 more source

Phenotypic characterization of cultured hBMSCs.

, 2013
hBMSCs are positive for CD73, CD146, CD105, CD90 and Stro1. Open peaks indicate the isotype of each cell and solid peaks represent expression of each marker. Numbers in the box specify the percentage of positive cells as compared to isotype control.
Ram I. Mahato (317727), Vaibhav Mundra (477805), Hao Wu (65943)   +2 more
core   +1 more source

Human Bone Marrow Stromal Cells Differentiate into Corneal Tissue and Prevent Ocular Graft-Versus-Host Disease in Mice

Cell Transplantation, 2015
Clinical trials have assessed the use of human bone marrow stromal cells (hBMSCs) for the treatment of immune-related disorders such as graft-versus-host disease (GVHD).
Luis Ignacio Sánchez-Abarca, Emiliano Hernández-Galilea M.D., Rebeca Lorenzo, Carmen Herrero, Almudena Velasco, Soraya Carrancio, Teresa Caballero-Velázquez, José Ignacio Rodríguez-Barbosa, Marta Parrilla, Consuelo Del Cañizo, Jesús San Miguel, José Aijón, José Antonio Pérez-Simón M.D., Ph.D.   +12 more
doaj   +1 more source

Human Bone Marrow Stromal Cells can Differentiate to a Retinal Pigment Epithelial Phenotype when Co-Cultured with Pig Retinal Pigment Epithelium using a Transwell System

Cellular Physiology and Biochemistry, 2013
Background: There is an increasing interest in generating retinal pigment epithelial (RPE) cells from stem cells for therapy against degenerative eye diseases.
Ping Duan, Haiwei Xu, Yuxiao Zeng, Yi Wang, Zheng Qin Yin   +4 more
doaj   +1 more source

SPEMF increases the mineralization of hBMSCs.

, 2014
SPEMF 1–25 groups were stimulated with SPEMF from day 1 to day 25, while SPEMF 1–7 groups were stimulated from day 1 to day 7. Calcification deposits were collected on the 10th, 15th, 20th, and 25th day.
Chih-Chun Lin (535872), Je-Ken Chang (535873), Mei-Ling Ho (103141), Chung-Hwan Chen (535874), Gwo-Jaw Wang (137967), Yin-Chih Fu (535871), I-Chun Tai (535875)   +6 more
core   +1 more source

Stimulation of osteogenesis and angiogenesis of hBMSCs by delivering Si ions and functional drug from mesoporous silica nanospheres

, 2015
Multifunctional bioactive materials with the ability to stimulate osteogenesis and angiogenesis of stem cells play an important role in the regeneration of bone defects. However, how to develop such biomaterials remains a significant challenge.
Shi, Mengchao, Zhou, Yinghong, Shao, Jin, Chen, Zetao, Wu, Chengtie, Xiao, Yin, Song, Botao, Chang, Jiang   +7 more
core   +1 more source

System-wide survey of proteomic responses of human bone marrow stromal cells (hBMSCs) to in vitro cultivation [PDF]

, 2015
Human bone marrow stromal cells (hBMSCs, also loosely called bone marrow-derived mesenchymal stem cells) are the subject of increasing numbers of clinical trials and laboratory research. Our group recently reported on the optimization of a workflow for a
Alterman, Michail A., Steven R. Bauer, Mindaye, Samuel T., Samuel T. Mindaye, Surdo, Jessica Lo, Jessica Lo Surdo, Bauer, Steven R., Michail A. Alterman   +7 more
core   +1 more source

Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges

BMEMat, EarlyView.
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma, Nan Jiang, Liyuan Chen, He Zhang, Xinjia Cai, Karan Gulati, Danqing He, Zhigang Cai, Yan Liu   +8 more
wiley   +1 more source

ALP and RUNX2 expression of hBMSCs on Ta and Ti coatings with osteogenic induction.

, 2013
(A) Odyssey scanning of the ALP protein expression in hBMSCs on the coatings with DRAQ5 as reference, 12 days. (B) ALP activity stain assay of hBMSCs on the coatings in 3, 7, 15, and 21 days with a white light scanner and near-infrared Odyssey scanner ...
Youtao Xie (420382), Yan Huang (46805), Fei Yang (46361), Xuebin Zheng (386179), Kerong Dai (387141), Chuandong Wang (420383), Ze Tang (420381), Xiaoling Zhang (420384)   +7 more
core   +1 more source

Silencing HIF-1α reduces the adhesion and secretion functions of acute leukemia hBMSCs [PDF]

Brazilian Journal of Medical and Biological Research, 2012
Hypoxia inducible factor-1α (HIF-1α) is an important transcription factor, which plays a critical role in the formation of solid tumor and its microenvironment. The objective of the present study was to evaluate the expression and function of HIF-1α in human leukemia bone marrow stromal cells (BMSCs) and to identify the downstream targets of HIF-1α ...
Dong-Feng, Zeng, Ting, Liu, Cheng, Chang, Xi, Zhang, Xue, Liang, Xing-Hua, Chen, Pei-Yan, Kong   +6 more
openaire   +5 more sources