Results 31 to 40 of about 5,228 (216)

Injectable platelet-rich fibrin positively regulates osteogenic differentiation of stem cells from implant hole via the ERK1/2 pathway

Platelets, 2023
Bone regeneration in dentistry is a dynamic approach for treating critical size bone defects that are unlikely to self-heal. Human bone marrow stem cell (hBMSCs) therapies are being tested clinically for various disorders and have remarkable clinical ...
Jia Wang, Wanxin Li, Xuxia He, Simei Li, Hongwei Pan, Lihua Yin   +5 more
doaj   +1 more source

Cell Membrane Vesicles Derived from Hbmscs and Huvecs Enhance Bone Regeneration

Bone Research, 2023
Abstract Bone tissue renewal can be enhanced through co-transplantation of bone mesenchymal stem cells (BMSCs) and vascular endothelial cells (ECs). However, there are apparent limitations in stem cell-based therapy which hinder its clinic translation.
Dandan Wang, Yaru Guo, Boon Chin Heng, Xuehui Zhang, Yan Wei, Ying He, Mingming Xu, Bin Xia, Xuliang Deng   +8 more
openaire   +3 more sources

Influence of Kartogenin on Chondrogenic Differentiation of Human Bone Marrow-Derived MSCs in 2D Culture and in Co-Cultivation with OA Osteochondral Explant

Molecules, 2018
Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect on in vitro proliferation and chondrogenic differentiation of human
Timea Spakova, Jana Plsikova, Denisa Harvanova, Marek Lacko, Stefan Stolfa, Jan Rosocha   +5 more
doaj   +1 more source

KCNQ1OT1 regulates osteogenic differentiation of hBMSC by miR-320a/Smad5 axis.

European review for medical and pharmacological sciences, 2020
Osteogenic differentiation plays a crucial role in maintaining general bone homeostasis. Long non-coding RNAs (lncRNAs) and microRNAs (miRNAs) act as important regulators during the osteogenesis process. This study aimed to elucidate the mechanism of Potassium voltage-gated channel subfamily Q member 1 overlapping transcript 1 (KCNQ1OT1) in osteogenic ...
Wang, J.-L., Wei, X., Wang, A.-G., Bai, Y., Wu, X.-J.   +4 more
openaire   +2 more sources

Nanotopography-Mediated Mechanotransduction Enhances hBMSCs Adhesion on TiO₂ Nanotubes. [PDF]

J Funct Biomater
Titanium and its alloys are widely used for orthopedic implants, but their intrinsic bioinertness may hinder osseointegration. In this study, titanium dioxide nanotube (TNT) arrays were fabricated on Ti-6Al-4V scaffolds via anodization, and their effects on the adhesion behavior of human bone marrow mesenchymal stem cells (hBMSCs) were investigated ...
Xiong C, Feng H, Lu L, Jing Z, Wang Y, Yang Y, Meng D, Zhang Y, Li W, Cai H.   +9 more
europepmc   +2 more sources

miR-215-5p regulates osteoporosis development and osteogenic differentiation by targeting XIAP

BMC Musculoskeletal Disorders, 2022
Background Osteoporosis (OP) is a metabolic disease that involves microstructure destruction and fracture damage. The present study probed into the significance of miR-215-5p in OP progression.
Zilong Yin, Jian Shen, Qiang Wang, Liangyuan Wen, Wenjing Qu, Yaonan Zhang   +5 more
doaj   +1 more source

Lithium release from ß-tricalcium phosphate inducing cementogenic and osteogenic differentiation for both hPDLCs and hBMSCs

, 2014
It is accepted that the accelerated differentiation of tissue cells on bioactive materials is of great importance to regenerate the lost tissues.
Han , Pingping, Chakravorty, Nishant, Wu, Chengtie, Xiao, Yin, Xu, Mengchi, Chang, Jiang   +5 more
core   +1 more source

Schematic diagram of targeted gene delivery to hBMSCs.

, 2013
Schematic diagram of targeted gene delivery to hBMSCs.
Zaibo Jiang (467729), Chun Wu (237024), Kangshun Zhu (419347), Min Shen (68726), Xintao Shuai (90605), Pengfei Pang (419346), Faming Gong (419345), Shouhai Guan (467730), Hong Shan (419350)   +8 more
core   +1 more source

Bone marrow mesenchymal stem cells transplantation promotes the release of endogenous erythropoietin after ischemic stroke

Neural Regeneration Research, 2015
This study investigated whether bone marrow mesenchymal stem cell (BMSC) transplantation protected ischemic cerebral injury by stimulating endogenous erythropoietin.
Wen Lv, Wen-yu Li, Xiao-yan Xu, Hong Jiang, Oh Yong Bang   +4 more
doaj   +1 more source

Effect of RG108 on apoptosis in hBMSCs.

, 2018
(A, B) hBMSCs were treated for 3 and 7 days with 50 μM and 100 μM RG108 and compared to DMEM and DMSO controls. Neither of the treatments triggered cell death by apoptosis at 3 and 7 days.
Geórgia da Silva Feltran (4089847), Karina G. Silvério (6037934), Enilson A. Sallum (2697061), Malgorzata Wiench (6037931), Rodrigo A. da Silva (6037937), Francisco H. Nociti Jr (6037940), Rahyza I. F. Assis (6037928), Denise C. Andia (6037943), Marcio Z. Casati (3878761)   +8 more
core   +1 more source