Results 31 to 40 of about 6,219 (219)

Human mesenchymal stem cells response to multi-doped silicon-strontium calcium phosphate coatings [PDF]

, 2014
The search for apatitic calcium phosphate coatings to improve implants osteointegration is, nowadays, preferentially focused in the obtaining of compositions closer to that of the inorganic phase of bone. Silicon and strontium are both present in trace
González, P., Lopéz-Álvarez, M., Marques, A. P., Pereiro, Iago, Pirraco, Rogério, Reis, R. L., Rodríguez-Valencia, Cosme, Serra, J.   +7 more
core   +1 more source

Regulation of Human Bone Marrow Stromal Cell Proliferation and Differentiation Capacity by Glucocorticoid Receptor and AP-1 Crosstalk [PDF]

, 2010
Although marrow adipocytes and osteoblasts derive from a common bone marrow stromal cells (BMSCs), the mechanisms that underlie osteoporosis-associated bone loss and marrow adipogenesis during prolonged steroid treatment are unclear.
Angel, Bar-Shavit, Barrett, Beato, Carcamo-Orive, Coghlan, Dass, Duque, Ecklund, Herber, Hollinger, Jonat, Kang, Lian, Liu, Mariani, McKay, Minaire, Neubauer, Papachristou, Pierotti, Pittenger, Rosen, Rosen, Sanchez, Schule, Sotiropoulou, Stein, Vayssiere, Vig, Wang, Wang, Wei, Weinstein, Wiznerowicz, Wlodarski, Wronski, Yang-Yen, Zayzafoon, Zhang   +39 more
core   +1 more source

On the use of dexamethasone-loaded liposomes to induce the osteogenic differentiation of human mesenchymal stem cells [PDF]

, 2015
Article first published online: 7 Oct. 2013Stem cells have received considerable attention by the scientific community because of their potential for tissue engineering and regenerative medicine.
Allen, Almeida, Asgeirdottir, Balmayor, Balmayor, Balmayor, Bhardwaj, Chen, Chono, Chono, Crielaard, Delorme, Diebold, Drummond, Duarte, Elron-Gross, Engler, Gabizon, Goldberg, Gomes-da-Silva, Hegeman, Hristova, Huang, Jaiswal, Jass, Kale, Katayama, Kim, Kulkarni, Lee, Leong-Poi, Li, Liu, Loughrey, Martins, Mickova, Moreira, Moura, Oliveira, Oliveira, Oliveira, Park, Park, Pjanović, Santo, Shi, Song, Tan, Torchilin, Tsotas, Wu, Yousefi, Zheng   +52 more
core   +1 more source

LncRNA MEG3 promotes osteogenesis of hBMSCs by regulating miR-21-5p / SOD3 axis

Acta Biochimica Polonica, 2022
Background: This study aimed to investigate the role of long non-coding (Lnc) RNA MEG3 on the osteogenesis of human bone marrow mesenchymal stem cells (hBMSCs). Materials and Methods: The binding of miR-21-5p to LncRNA MEG3 and SOD3 was determined using luciferase reporter assay; fluorescence quantitative PCR was used to detect the expression of LncRNA
Shuangli, Wang, Gaoxin, Xiong, Rende, Ning, Zhengjun, Pan, Meihua, Xu, Zhengang, Zha, Ning, Liu   +6 more
openaire   +3 more sources

Human cartilage engineering in an in vitro repair model using collagen scaffolds and mesenchymal stromal cells [PDF]

, 2017
[Abstract] The purpose of this study was to investigate cartilage repair of in vitro lesion models using human bone marrow mesenchymal stromal cells (hBMSCs) with different collagen (Col) scaffolds.
Blanco García, Francisco J, Castro Viñuelas, Rocío, De-Toro, Javier, Díaz-Prado, Silvia, Fuentes Boquete, Isaac Manuel, Hermida Gómez, Tamara, Sanjurjo-Rodríguez, Clara   +6 more
core   +2 more sources

Influence of Kartogenin on Chondrogenic Differentiation of Human Bone Marrow-Derived MSCs in 2D Culture and in Co-Cultivation with OA Osteochondral Explant

Molecules, 2018
Articular cartilage has limited capacity for natural regeneration and repair. In the present study, we evaluated kartogenin (KGN), a bioactive small heterocyclic molecule, for its effect on in vitro proliferation and chondrogenic differentiation of human
Timea Spakova, Jana Plsikova, Denisa Harvanova, Marek Lacko, Stefan Stolfa, Jan Rosocha   +5 more
doaj   +1 more source

Hyaluronic acid/poly-L-lysine bilayered silica nanoparticles enhance the osteogenic differentiation of human mesenchymal stem cells [PDF]

, 2014
First published online 15 Aug 2014Herein, we evaluate the influence of a PLL–HA bilayer on the surface of silica nanoparticles on their capacity to induce the osteogenic differentiation of human bone marrow stem cells (hBMSCs), as a function of their ...
Amorim, Sara, Martins, Albino, Neves, N. M., Pires, R. A., Reis, R. L.   +4 more
core   +1 more source

CD24 reguliert immunmodulatorische Eigenschaften in hBMSCs

, 2017
Fragestellung: Humane mesenchymale Stammzellen aus dem Knochenmark (hBMSCs) können in Abhängigkeit von Zytokinen oder Pathogen-assoziierten molekularen Mustern (PAMPs) einen immunsuppressiven oder immunstimulierenden Phänotyp ausbilden. Unsere Arbeitsgruppe konnte zeigen, dass das Glykoprotein[zum vollständigen Text gelangen Sie über die oben ...
Schäck, LM, Noack, S, Krettek, C, Neunaber, C   +3 more
openaire   +2 more sources

Directed differentiation of human bone marrow stromal cells to fate-committed Schwann cells [PDF]

, 2017
Transplantation of oligodendrocyte precursors represents a potential therapy for myelin disorders but requires a safe and accessible cell source. Here we report the directed differentiation of neural progenitors derived from adult bone marrow stromal ...
Ao, Q, Cai, S, Chan, YS, Chang, RSK, Shea, GKH, Shum, DKY, Tam, KW, Tsui, YP   +7 more
core   +2 more sources

CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment

International Journal of Molecular Sciences, 2020
Near the bone remodeling compartments (BRC), extracellular calcium concentration (Ca2+o) is locally elevated and bone marrow stromal cells (BMSCs) close to the BRC can be exposed to high calcium concentration. The calcium-sensing receptor (CaSR) is known to play a key role in maintaining extracellular calcium homeostasis by sensing fluctuations in the ...
Hyunji Cho, Jisoo Lee, Seoyoung Jang, Jungsun Lee, Tong In Oh, Youngsook Son, EunAh Lee   +6 more
openaire   +2 more sources