Results 11 to 20 of about 5,228 (216)

Effect of monocytes/macrophages on the early osteogenic differentiation of hBMSCs [PDF]

open access: yesJournal of Tissue Engineering and Regenerative Medicine, 2012
Heterotypic cell interactions are essential for the homeostasis of bone tissue, in particular the widely studied interaction between osteoblasts and osteoclasts. Closely related with osteoclasts are monocytes/macrophages. These have been shown to produce
Pirraco, Rogério P.   +5 more
core   +3 more sources

Overexpression of RPN2 promotes osteogenic differentiation of hBMSCs through the JAK/STAT3 pathway [PDF]

open access: yesFEBS Open Bio, 2020
Osteoporosis is characterized by decreased bone mass and degenerating bone structure, which cause severe bone fragility and increase the risk for fractures.
Jianhua Yu   +6 more
core   +4 more sources

CaSR-Mediated hBMSCs Activity Modulation: Additional Coupling Mechanism in Bone Remodeling Compartment

open access: yesInternational Journal of Molecular Sciences, 2020
Near the bone remodeling compartments (BRC), extracellular calcium concentration (Ca2+o) is locally elevated and bone marrow stromal cells (BMSCs) close to the BRC can be exposed to high calcium concentration. The calcium-sensing receptor (CaSR) is known
Tong In Oh   +6 more
core   +3 more sources

Atractylodes Macrocephala Koidz. Derived Exosome-Like Nanovesicles Promoted Osteogenic Differentiation of hBMSCs Via Regulating SOD2 and Postponed Osteoporosis of Ovariectomized Rats

open access: yesEuropean Cells & Materials
Objective: Osteoporosis is a chronic disease associated with decreased bone strength and a heightened susceptibility to fractures. Atractylodes macrocephala Koidz.
Ziquan Zhao   +9 more
doaj   +2 more sources

TMT-Based Proteomic Explores the Influence of DHEA on the Osteogenic Differentiation of hBMSCs [PDF]

open access: yesFrontiers in Cell and Developmental Biology, 2021
Dehydroepiandrosterone (DHEA) has been revealed to implicate in facilitating osteoblast differentiation of human bone marrow mesenchymal stem cells (hBMSCs) and inhibiting osteoporosis (OP). However, the underlying molecular mechanism remains largely unknown.
Xiaonan Liang   +6 more
openaire   +3 more sources

Ubiquitin-specific protease 53 promotes osteogenic differentiation of human bone marrow-derived mesenchymal stem cells

open access: yesCell Death and Disease, 2021
The ubiquitin protease pathway plays important role in human bone marrow-derived mesenchymal stem cell (hBMSC) differentiation, including osteogenesis.
Dawoon Baek   +6 more
doaj   +1 more source

Characterization of Human, Ovine and Porcine Mesenchymal Stem Cells from Bone Marrow: Critical In Vitro Comparison with Regard to Humans

open access: yesLife, 2023
For research and clinical use of stem cells, a suitable animal model is necessary. Hence, the aim of this study was to compare human-bone-marrow-derived mesenchymal stem cells (hBMSCs) with those from sheep (oBMSCs) and pigs (pBMSCs).
Elisa Katja Westerkowsky   +6 more
doaj   +1 more source

A comparative study of HAMSCs/HBMSCs transwell and mixed coculture systems [PDF]

open access: yesIUBMB Life, 2019
AbstractOur previous studies indicated that a coculture system containing human amnion‐derived mesenchymal stem cells (HAMSCs) and human bone marrow mesenchymal stem cells (HBMSCs) has the potential of application for bone regeneration. However, there is currently no enough comparative investigation between HAMSCs/HBMSCs transwell and mixed coculture ...
Yifeng Bian   +6 more
openaire   +2 more sources

Genetically modified human bone marrow derived mesenchymal stem cells for improving the outcome of human islet transplantation. [PDF]

open access: yesPLoS ONE, 2013
The objective of this study was to determine the potential of human bone marrow derived mesenchymal stem cells (hBMSCs) as gene carriers for improving the outcome of human islet transplantation.
Vaibhav Mundra, Hao Wu, Ram I Mahato
doaj   +1 more source

Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality [PDF]

open access: yesBiomaterials, 2010
Electrospun structures were proposed as scaffolds owing to their morphological and structural similarities with the extracellular matrix found in many native tissues. These fibrous structures were also proposed as drug release systems by exploiting the direct dependence of the release rate of a drug on the surface area.
Martins, Albino   +5 more
openaire   +3 more sources

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