Results 11 to 20 of about 3,978 (176)
Biochemistry and Biophysics Reports, 2023 Introduction: In this study, we report that a proteoglycans (PGs)-layer between the bone and titanium dioxide (TiO2) surface after osseointegration improved the calcification capacity and immunotolerance of human bone marrow mesenchymal stem cells ...
Tomomi Mizutani +8 more
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Journal of Investigative Surgery, 2023 Background: In this study, we aimed to explore whether the SRY-box transcription factor 9 (SOX9) can play protective roles against the occurrence and development of osteonecrosis of the femoral head (ONFH) by regulating the proliferation, apoptosis, and ...
Xiangsheng Meng, Haiquan Zhu
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Cell Death and Disease, 2021 The ubiquitin protease pathway plays important role in human bone marrow-derived mesenchymal stem cell (hBMSC) differentiation, including osteogenesis.
Dawoon Baek +6 more
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Life, 2023 For research and clinical use of stem cells, a suitable animal model is necessary. Hence, the aim of this study was to compare human-bone-marrow-derived mesenchymal stem cells (hBMSCs) with those from sheep (oBMSCs) and pigs (pBMSCs).
Elisa Katja Westerkowsky +6 more
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Osteogenic induction of hBMSCs by electrospun scaffolds with dexamethasone release functionality [PDF]
Biomaterials, 2010 Electrospun structures were proposed as scaffolds owing to their morphological and structural similarities with the extracellular matrix found in many native tissues. These fibrous structures were also proposed as drug release systems by exploiting the direct dependence of the release rate of a drug on the surface area.
Martins, Albino +5 more
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Genetically modified human bone marrow derived mesenchymal stem cells for improving the outcome of human islet transplantation. [PDF]
PLoS ONE, 2013 The objective of this study was to determine the potential of human bone marrow derived mesenchymal stem cells (hBMSCs) as gene carriers for improving the outcome of human islet transplantation.
Vaibhav Mundra, Hao Wu, Ram I Mahato
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A comparative study of HAMSCs/HBMSCs transwell and mixed coculture systems [PDF]
IUBMB Life, 2019 AbstractOur previous studies indicated that a coculture system containing human amnion‐derived mesenchymal stem cells (HAMSCs) and human bone marrow mesenchymal stem cells (HBMSCs) has the potential of application for bone regeneration. However, there is currently no enough comparative investigation between HAMSCs/HBMSCs transwell and mixed coculture ...
Yifeng Bian +6 more
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DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes
Stem Cell Research, 2020 Biliary injury is one of the main pathological mechanisms of fulminant hepatic failure (FHF). Delta-like ligand 4 (DLL4)-mediated Notch activation contributes to reversing biliary injury; however, the specific role of DLL4 in biliary restoration is still unclear.
Suwan Sun +15 more
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Frontiers in Cell and Developmental Biology, 2021 Human bone marrow-derived mesenchymal stem cells (hBMSCs) and their derivative enhanced green fluorescent protein (eGFP)-hBMSCs were employed to evaluate an innovative hybrid scaffold composed of granular hydroxylapatite and collagen hemostat (Coll/HA ...
Elisa Mazzoni +13 more
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Involvement of CB2 signalling pathway in the development of osteoporosis by regulating the proliferation and differentiation of hBMSCs [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractThe aim of the present study was to explore the potential mechanism underlying the involvement of CB2 in osteoporosis. Micro‐CT was utilized to examine femur bone architecture. Also, real‐time PCR and Western blot analysis were utilized to detect the effect of 2‐AG on the expression of CB2 and Notch, or the interaction between CB2 and Notch 2 ...
Feng Tian +4 more
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