Results 21 to 30 of about 5,228 (216)
Frontiers in Cell and Developmental Biology, 2021 Human bone marrow-derived mesenchymal stem cells (hBMSCs) and their derivative enhanced green fluorescent protein (eGFP)-hBMSCs were employed to evaluate an innovative hybrid scaffold composed of granular hydroxylapatite and collagen hemostat (Coll/HA ...
Elisa Mazzoni +13 more
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Involvement of CB2 signalling pathway in the development of osteoporosis by regulating the proliferation and differentiation of hBMSCs [PDF]
Journal of Cellular and Molecular Medicine, 2021 AbstractThe aim of the present study was to explore the potential mechanism underlying the involvement of CB2 in osteoporosis. Micro‐CT was utilized to examine femur bone architecture. Also, real‐time PCR and Western blot analysis were utilized to detect the effect of 2‐AG on the expression of CB2 and Notch, or the interaction between CB2 and Notch 2 ...
Feng Tian +4 more
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Stem Cell Research & Therapy, 2021 Background Stem cells are the main choice for seed cells in tissue engineering, but using most traditional stem cells requires invasive and complicated procedures.
Jiachen Sun +5 more
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Cellular Physiology and Biochemistry, 2014 Background/Aims: Human bone-marrow mesenchymal stem cells (hBMSCs) are widely transplanted into inflammatory microenvironment to accelerate tissue regeneration. Transplanted hBMSCs recruit host hBMSCs through a poorly understood mechanism. This study was
Junchao Xing +7 more
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DLL4 restores damaged liver by enhancing hBMSC differentiation into cholangiocytes
Stem Cell Research, 2020 Biliary injury is one of the main pathological mechanisms of fulminant hepatic failure (FHF). Delta-like ligand 4 (DLL4)-mediated Notch activation contributes to reversing biliary injury; however, the specific role of DLL4 in biliary restoration is still unclear.
Suwan Sun +15 more
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Stem Cell Reports, 2014 Because of their immunomodulatory properties, human bone marrow stromal cells (hBMSCs) represent promising stem cells for treatment of immune disorders.
Rene Rodriguez +7 more
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Stem Cells International, 2023 Human bone marrow-derived mesenchymal stem cells (hBMSCs) are promising candidates for stem cell therapy in clinical trials. Applications of hBMSCs in clinical therapy are limited by cellular senescence due to long-term ex vivo expansion.
Pingting Ye +7 more
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Comparison of hIGF-1 Gene Transfection to the hBMSCs and Human Meniscal Fibrochondrocytes [PDF]
Medical Science Monitor, 2015 Treatment strategies for meniscal injury are shifting from meniscectomy to repair, especially cell-based therapy. Delivering selected genes to donor cells can modify differentiation and proliferation. Efficiency of gene transfection and expression may relate to cell type.Full-length hIGF-1 cDNA was cloned into eukaryotic expression vector by PCR. Human
Zhang, Haining +3 more
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RNF4~RGMb~BMP6 axis required for osteogenic differentiation and cancer cell survival
Cell Death and Disease, 2022 Molecular understanding of osteogenic differentiation (OD) of human bone marrow-derived mesenchymal stem cells (hBMSCs) is important for regenerative medicine and has direct implications for cancer.
Rostislav Novak +13 more
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Cells, 2022 Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone ...
Chenglong Wang +7 more
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