Results 51 to 60 of about 305,562 (334)

Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer

OncoImmunology
Macrophages are pivotal in driving breast tumor development, progression, and resistance to treatment, particularly in estrogen receptor-positive (ER+) tumors, where they infiltrate the tumor microenvironment (TME) influenced by cancer cell-secreted ...
Sanghoon Lee, Youngbin Cho, Yiting Li, Ruxuan Li, Angela Wong Lau, Matthew S. Laird, Daniel Brown, Priscilla McAuliffe, Adrian V. Lee, Steffi Oesterreich, Ioannis K. Zervantonakis, Hatice Ulku Osmanbeyoglu   +11 more
doaj   +1 more source

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection [PDF]

, 2018
Previous studies have detected a higher level of ferritin in patients with hepatocellular carcinoma (HCC), but a potential causal association between serum ferritin level and hepatocarcinogenesis remains to be clarified.
Bian, Zhenyuan, Fang, Wan, Hann, Hie-Won, Tao, Kaishan, Wan, Shaogui, Wang, Chun, Wang, Yang, Ye, Zhong, Yin, Chun   +8 more
core   +1 more source

TRERNA1 upregulation mediated by HBx promotes sorafenib resistance and cell proliferation in HCC via targeting NRAS by sponging miR-22-3p [PDF]

, 2021
Wei Song, Chuqian Zheng, Min Liu, Ying Xu, Yanyan Qian, Zhihong Zhang, Hongmeng Su, Xinxiu Li, Huazhang Wu, Pihai Gong, Yiping Li, Hong Fan   +11 more
openalex   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Co-Administration of iRGD with Sorafenib-Loaded Iron-Based Metal-Organic Framework as a Targeted Ferroptosis Agent for Liver Cancer Therapy

International Journal of Nanomedicine, 2021
Xianchuang Liu,1 Xinyang Zhu,1 Xun Qi,1 Xianwei Meng,2 Ke Xu1 1Department of Radiology and Key Laboratory of Diagnostic Imaging and Interventional Radiology of Liaoning Province, The First Affiliated Hospital of China Medical University, Shenyang ...
Liu X, Zhu X, Qi X, Meng X, Xu K
doaj  

Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model

Disease Models & Mechanisms, 2019
Tumors are frequently dependent on primary oncogenes to maintain their malignant properties (known as ‘oncogene addiction’). We have previously established several inducible hepatocellular carcinoma (HCC) models in zebrafish by transgenic expression of ...
Yan Li, Ira Agrawal, Zhiyuan Gong
doaj   +1 more source

Primary Human Tissue Models for Metabolic Dysfunction‐Associated Liver Disease ‐ toward Streamlining Drug Discovery with Patient‐Derived Assays

Advanced Biology, EarlyView.
The review provides a critical up‐to‐date overview of the current landscape of human in vitro models for fatty liver disease, including spheroids, organoids, organ‐on‐a‐chip systems, bioprinted liver constructs and precision‐cut liver slices. Their utility for faithfully modeling different stages of MASLD and MASH are evaluated and their compatibility ...
Sonia Youhanna, Nayere Taebnia, Yingxin Liang, Ningtao Cheng, Yi Wang, Maurice Michel, Volker M. Lauschke   +6 more
wiley   +1 more source

Respiration-Induced Intraorgan Deformation of the Liver: Implications for Treatment Planning in Patients Treated With Fiducial Tracking. [PDF]

, 2017
Stereotactic body radiation therapy is a well-tolerated modality for the treatment of primary and metastatic liver lesions, and fiducials are often used as surrogates for tumor tracking during treatment. We evaluated respiratory-induced liver deformation
Anwar, Mekhail, Chang, Albert J, Descovich, Martina, Gottschalk, Alexander R, Paulsson, Anna K, Pinnaduwage, Dilini, Sudhyadhom, Atchar, Yom, Sue S   +7 more
core   +1 more source

A model based on adipose and muscle-related indicators evaluated by CT images for predicting microvascular invasion in HCC patients [PDF]

, 2023
Xin‐Cheng Mao, Shuo Shi, Lun‐Jie Yan, Hanchao Wang, Zi‐Niu Ding, Hui Liu, Guoqiang Pan, Xiao Zhang, Cheng‐Long Han, Bao‐Wen Tian, Dongxu Wang, Si-Yu Tan, Zhao‐Ru Dong, Yu‐Chuan Yan, Tao Li   +14 more
openalex   +1 more source

Optimizing (1‐x) BiFeO3‐xCaTiO3 Perovskites: A Pathway to Efficient Flexible Energy Storage

Advanced Functional Materials, EarlyView.
Perovskite materials, like BFO CTO, are popular due to their high conductivity, low cost, and wide availability. In this work a symmetric electrochemical cell based on BFO‐CTO shows a charge of 3.356 C.cm⁻2, giving a specific capacitance of 2.79 mF.cm⁻2 at 1 mV.s⁻2.
Febin Paul, Shahina Shareef, Eric Kumi Barimah, Mustehsan Beg, Keng Goh, Gin Jose, Zhilun Lu, Libu Manjakkal   +7 more
wiley   +1 more source