Results 51 to 60 of about 289,858 (341)

Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer

OncoImmunology
Macrophages are pivotal in driving breast tumor development, progression, and resistance to treatment, particularly in estrogen receptor-positive (ER+) tumors, where they infiltrate the tumor microenvironment (TME) influenced by cancer cell-secreted ...
Sanghoon Lee, Youngbin Cho, Yiting Li, Ruxuan Li, Angela Wong Lau, Matthew S. Laird, Daniel Brown, Priscilla McAuliffe, Adrian V. Lee, Steffi Oesterreich, Ioannis K. Zervantonakis, Hatice Ulku Osmanbeyoglu   +11 more
doaj   +1 more source

MicroRNAs in Animal Models of HCC [PDF]

Cancers, 2019
Hepatocellular carcinoma (HCC) is the second leading cause of cancer-related mortality. Molecular heterogeneity and absence of biomarkers for patient allocation to the best therapeutic option contribute to poor prognosis of advanced stages. Aberrant microRNA (miRNA) expression is associated with HCC development and progression and influences drug ...
Francesca Fornari, Laura Gramantieri, Elisa Callegari, Ram C. Shankaraiah, Fabio Piscaglia, Massimo Negrini, Catia Giovannini   +6 more
openaire   +3 more sources

Ferritin level prospectively predicts hepatocarcinogenesis in patients with chronic hepatitis B virus infection [PDF]

, 2018
Previous studies have detected a higher level of ferritin in patients with hepatocellular carcinoma (HCC), but a potential causal association between serum ferritin level and hepatocarcinogenesis remains to be clarified.
Bian, Zhenyuan, Fang, Wan, Hann, Hie-Won, Tao, Kaishan, Wan, Shaogui, Wang, Chun, Wang, Yang, Ye, Zhong, Yin, Chun   +8 more
core   +1 more source

Impact of previous hepatitis B infection on the clinical outcomes from chronic hepatitis C? A population-level analysis [PDF]

, 2018
Chronic coinfection with hepatitis C virus (HCV) and hepatitis B virus (HBV) is associated with adverse liver outcomes. The clinical impact of previous HBV infection on liver disease in HCV infection is unknown. We aimed at determining any association of
Allen, S., Barclay, S. T., Bhattacharyya, D., Dillon, J. F., Fox, R., Fraser, A., Gunson, R., Hayes, P. C., Hunt, A., Hutchinson, S. J., Innes, H. A., Kennedy, N., Mcintrye, P. G., Mills, P. R., Morris, J., Stanley, A. J., Swann, R., Thomas, E., Valerio, H., Wang, H., Wilks, D.   +20 more
core   +4 more sources

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

The EGFR Polymorphism Increased the Risk of Hepatocellular Carcinoma Through the miR-3196-Dependent Approach in Chinese Han Population

Pharmacogenomics and Personalized Medicine, 2021
Li Zhang, Xiaoping Li, Jiang Lu, Yi Qian, Tao Qian, Xing Wu, Qinghua Xu Department of Hepatobiliary and Pancreatic Surgery, LiYang People’s Hospital, LiYang, 213300, Jiangsu, People’s Republic of ChinaCorrespondence: Qinghua Xu; Xing ...
Zhang L, Li X, Lu J, Qian Y, Qian T, Wu X, Xu Q   +6 more
doaj  

Prolonged post-ablation fever may predict one-year tumor recurrence in hepatocellular carcinoma after radiofrequency ablation

International Journal of Hyperthermia, 2020
Background The impact of prolonged post-ablation fever (PAF) defined as persistent fever > 24 h after radiofrequency ablation (RFA) for hepatocellular carcinoma (HCC) had not been described before.
Ping-Hung Ho, Wei Teng, Chen-Chun Lin, Wen-Juei Jeng, Wei-Ting Chen, Chun-Yen Lin, Shi-Ming Lin, I-Shyan Sheen   +7 more
doaj   +1 more source

EMT and Inflammation: Crossroads in HCC

Journal of Gastrointestinal Cancer, 2022
Hepatocellular carcinoma is one of the major causes of cancer-related deaths worldwide and is associated with several inflammatory mediators, since 90% of HCCs occur based on chronic hepatitis B or C, alcoholism or increasingly metabolic syndrome-associated inflammation.
Burcu Sengez, Brian I. Carr, Hani Alotaibi   +2 more
openaire   +4 more sources

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source

Timing of DAA Initiation After Curative Treatment and Its Relationship with the Recurrence of HCV-Related HCC

Journal of Hepatocellular Carcinoma, 2020
Xiuzhu Gao,1,2,* Mengru Zhan,1,* Liquan Wang,3 Yanhua Ding,2 Junqi Niu1 1Department of Hepatology, First Hospital of Jilin University, Changchun, Jilin 130021, People’s Republic of China; 2Phase I Clinical Research Center, The First Hospital of ...
Gao X, Zhan M, Wang L, Ding Y, Niu J
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