Results 51 to 60 of about 277,119 (298)
Медицинский совет, 2021 Introduction. HCC is a challenge for clinical oncology. 1-year mortality for advanced HCC accounts for 66% in theRussian Federation. The results obtained in the combined Atezolizumab and Bevacizumab therapy in the advanced HCC cases are reported ...
I. А. Dzhanyan +2 more
doaj +1 more source
Gut, 2002 Choosing a scoring system for staging hepatocellular carcinoma is a difficult task Primary hepatocellular carcinoma (HCC) is a common neoplasm in East Asia, Africa, and the Mediterranean countries, with an age adjusted incidence rate of up to 20–28 cases per 105 in men.
openaire +3 more sources
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Cancer Management and Research, 2022 Wenqi Song,1,* Xuemei Zhang,2,* Lin Feng,1 Yongwei Lai,1 Tongtong Li,1 Pengxia Zhang1 1 Key Laboratory of Microecology-immune Regulatory Network and Related Diseases, School of Basic Medicine, Jiamusi University, Jiamusi, Heilongjiang, People’s ...
Song W +5 more
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Molecular Oncology, EarlyView.Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser +14 more
wiley +1 more source
Roles of circRNAs in the Tumorigenesis and Metastasis of HCC: A Mini Review
Cancer Management and Research, 2022 Yichen Liu, Lei Wang, Wen Liu Fujian Provincial Key Laboratory of Innovative Drug Target Research, School of Pharmaceutical Sciences, Xiamen University, Xiamen, Fujian, 361102, People’s Republic of ChinaCorrespondence: Yichen Liu; Wen Liu, Email yc-liu ...
Liu Y, Wang L, Liu W
doaj
FEBS Open Bio, EarlyView.CAF‐mediated immunosuppression in ovarian cancer is driven by IDO1, reducing T‐cell function. Inhibiting IDO1 restores T‐cell proliferation and cytotoxicity, increases cancer cell apoptosis, and may help overcome CAF‐induced immune suppression in high‐grade serous ovarian cancer. Targeting IDO1 may improve antitumor immunity.
Hyewon Lee +3 more
wiley +1 more source
Importancia del anestesiólogo en la prevención del dolor crónico [PDF]
Revista Chilena de Anestesia, 2021 Marcos Bolívar +4 more
doaj +1 more source
Cancer-cell derived S100A11 promotes macrophage recruitment in ER+ breast cancer
OncoImmunologyMacrophages are pivotal in driving breast tumor development, progression, and resistance to treatment, particularly in estrogen receptor-positive (ER+) tumors, where they infiltrate the tumor microenvironment (TME) influenced by cancer cell-secreted ...
Sanghoon Lee +11 more
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Overview of molecular signatures of senescence and associated resources: pros and cons
FEBS Open Bio, EarlyView.Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas +6 more
wiley +1 more source