Results 71 to 80 of about 1,778 (147)
Bacterial pathogenesis of plants: Future challenges from a microbial perspective [PDF]
, 2016 Plant infection is a complicated process. Upon encountering a plant, pathogenic microorganisms must first adapt to life on the epiphytic surface, and survive long enough to initiate an infection.
Caly, Delphine L. +2 more
core +1 more source
Identification of the YfgF MASE1 domain as a modulator of bacterial responses to aspartate [PDF]
, 2013 Complex 3'-5'-cyclic diguanylic acid (c-di-GMP) responsive regulatory networks that are modulated by the action of multiple diguanylate cyclases (DGC; GGDEF domain proteins) and phosphodiesterases (PDE; EAL domain proteins) have evolved in many bacteria.
Agasing, A. +3 more
core +1 more source
Movement Disorders, Volume 40, Issue 5, Page 928-937, May 2025.Abstract Background Antidopaminergic medications (ADM) are often used for symptom management of Huntington's disease (HD). Evidence from past research suggests that ADMs are associated with worse clinical outcomes in HD, but their impact on various domains remains underexplored.
Michal Geva +5 more
wiley +1 more source
Frontiers in MicrobiologyBacteria exhibit two lifestyles: planktonic, free-floating individual cells or sessile multicellular aggregates known as biofilms. The biofilm life cycle is characterized by three distinct stages: attachment, maturation and dispersal.
Xavier Bertran Forga +7 more
doaj +1 more source
High levels of cyclic di-GMP in Klebsiella pneumoniae attenuate virulence in the lung [PDF]
, 2018 The bacterial second messenger bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP) has been shown to influence the expression of virulence factors in certain pathogenic bacteria, but little is known about its activity in the increasingly antibiotic-resistant ...
Hunstad, David A +2 more
core +2 more sources
ChemBioChem, Volume 26, Issue 7, April 1, 2025.GSPII‐A is the first of three consecutive GSPII domains of PilF from Thermus thermophilus and the only one that does not bind c‐di‐GMP. In this study we solve the structure of GSPII‐A and show the key factors hindering c‐di‐GMP binding. Through mutagenesis, we elucidate the minimal motif conservation needed for c‐di‐GMP recognition. Abstract The cyclic
Konstantin Neißner +7 more
wiley +1 more source
Nucleotide second messengers in bacterial decision making [PDF]
, 2020 Since the initial discovery of bacterial nucleotide second messengers (NSMs), we have made huge progress towards understanding these complex signalling networks. Many NSM networks contain dozens of metabolic enzymes and binding targets, whose activity is
Malone, Jacob, Thompson, Catriona
core +1 more source
Microbial Biotechnology, Volume 18, Issue 4, April 2025.All 32 diguanylate cyclase (DGC)‐encoding genes of P. aeruginosa PA14 were interrupted by premature STOP codons, introduced through a multiplexed cytosine base‐editor. The synthesis of c‐di‐GMP was impaired in the resulting strain lacking all 32 DGCs (strain PA14Δ32). Phenotypic analysis confirmed major behaviour changes in P. aeruginosa PA14Δ32, which
Román A. Martino +5 more
wiley +1 more source
Roles of the second messenger cyclic di-GMP in environmental adaptation of Sinorhizobium meliloti [PDF]
, 2017 Bacteria have evolved various systems for the integration of environmental signals to rapidly coordinate cellular pathways and adapt to changes in their environment.
Schäper, Simon
core +1 more source
Balancing ecotourism and wildlife management through a conservation behavior approach
Conservation Science and Practice, Volume 7, Issue 3, March 2025.We surveyed ecologists, conservationists, and ecotourism professionals to investigate consequences of ecotourism on animal behavior. We highlight four main behavioral themes and solutions for engendering more sustainable ecotourism that mitigates behavioral impacts.
Rachel Y. Chock +22 more
wiley +1 more source