Results 51 to 60 of about 137,432 (128)
International Journal of Microbiology, Volume 2026, Issue 1, 2026.Nucleotide bis‐(3,5)‐cyclic di‐guanosine monophosphate (c‐di‐GMP) is a universal and versatile secondary messenger. It is involved in the regulation of significant functions such as motility, biofilm formation, virulence, drug resistance, cell cycle, differentiation, and many other physiological processes in bacteria.
Xiaojing Gao +7 more
wiley +1 more source
Farmland abandonment and season drive scavenging dynamics in livestock‐rewilded landscapes
Ecological Applications, Volume 35, Issue 8, December 2025.Abstract Farmland abandonment occurs commonly across European mountain regions, which causes triggering of habitat encroachment through shrub regeneration and natural afforestation. However, its impact on vertebrate scavenger communities and ecological processes, such as the removal of small carcasses remains poorly understood.
Rocío R. Daza +2 more
wiley +1 more source
Vibrio cholerae V‑cGAP3 Is an HD-GYP Phosphodiesterase with a Metal Tunable Substrate Selectivity
, 2022 Cyclic dinucleotides (CDNs) are signaling molecules involved in the immune response and virulence factor production. CDN cellular levels are fine-tuned by metal-dependent phosphodiesterases (PDEs), among which HD-GYPs make up a subclass of the larger HD ...
Sining Sun (8976038) +2 more
core +1 more source
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, Volume 5, Issue 9, September 2025.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source
, 2012 RpfG is a member of a class of wide spread bacterial two-component regulators with an HD-GYP cyclic di-GMP phosphodiesterase domain. In the plant pathogen Xanthomonas campestris, RpfG together with the sensor kinase RpfC regulates multiple factors as a ...
Farah, CS +14 more
core +1 more source
Movement Disorders, Volume 40, Issue 5, Page 928-937, May 2025.Abstract Background Antidopaminergic medications (ADM) are often used for symptom management of Huntington's disease (HD). Evidence from past research suggests that ADMs are associated with worse clinical outcomes in HD, but their impact on various domains remains underexplored.
Michal Geva +5 more
wiley +1 more source
A High-level EDA Environment for the Automatic Insertion of HD-BIST Structures [PDF]
, 2000 This paper presents a High-Level EDA environment based on the Hierarchical Distributed BIST (HD-BIST), a flexible and reusable approach to solve BIST scheduling issues in System-on-Chip applications.
Zorian Y. +5 more
core +1 more source
ChemBioChem, Volume 26, Issue 7, April 1, 2025.GSPII‐A is the first of three consecutive GSPII domains of PilF from Thermus thermophilus and the only one that does not bind c‐di‐GMP. In this study we solve the structure of GSPII‐A and show the key factors hindering c‐di‐GMP binding. Through mutagenesis, we elucidate the minimal motif conservation needed for c‐di‐GMP recognition. Abstract The cyclic
Konstantin Neißner +7 more
wiley +1 more source
Microbial Biotechnology, Volume 18, Issue 4, April 2025.All 32 diguanylate cyclase (DGC)‐encoding genes of P. aeruginosa PA14 were interrupted by premature STOP codons, introduced through a multiplexed cytosine base‐editor. The synthesis of c‐di‐GMP was impaired in the resulting strain lacking all 32 DGCs (strain PA14Δ32). Phenotypic analysis confirmed major behaviour changes in P. aeruginosa PA14Δ32, which
Román A. Martino +5 more
wiley +1 more source
Balancing ecotourism and wildlife management through a conservation behavior approach
Conservation Science and Practice, Volume 7, Issue 3, March 2025.We surveyed ecologists, conservationists, and ecotourism professionals to investigate consequences of ecotourism on animal behavior. We highlight four main behavioral themes and solutions for engendering more sustainable ecotourism that mitigates behavioral impacts.
Rachel Y. Chock +22 more
wiley +1 more source