Results 41 to 50 of about 1,778 (147)

The PAS domain-containing histidine kinase RpfS is a second sensor for the diffusible signal factor of Xanthomonas campestris [PDF]

, 2014
Summary: A cell-cell signalling system mediated by the fatty acid signal DSF controls the virulence of Xanthomonas campestris pv. campestris (Xcc) to plants. The synthesis and recognition of the DSF signal depends upon different Rpf proteins.
Allan, John H., An, Shi-Qi, Dow, J. Maxwell, Febrer, Melanie, McCarthy, Yvonne, Ryan, Robert P.   +5 more
core   +3 more sources

A Minimal Threshold of c-di-GMP Is Essential for Fruiting Body Formation and Sporulation in Myxococcus xanthus [PDF]

, 2016
Generally, the second messenger bis-(3’-5’)-cyclic dimeric GMP (c-di-GMP) regulates the switch between motile and sessile lifestyles in bacteria. Here, we show that c-di-GMP is an essential regulator of multicellular development in the social bacterium ...
A Duerig, A Konovalova, A Lu, AJ Schmidt, B Julien, BK Bharati, BY Chang, BY Matsuyama, BZ Harris, C Baraquet, C Spangler, CD Boyd, D Amikam, D Kaiser, D Skotnicka, D Srivastava, DA Ryjenkov, DA Ryjenkov, Dorota Skotnicka, E Bordeleau, E Trampari, Eleftheria Trampari, Gregory T. Smaldone, H Lancero, I Bulyha, I Letunic, IS Pultz, J Hodgkin, J Hodgkin, J Sambrook, Jacob G. Malone, Jennifer Liang, JJ Wilksch, Josep Casadesús, JP Massie, JT Pratt, JW Hickman, JW Hickman, KG Roelofs, KH Chin, L Hobley, L Jelsbak, L Søgaard-Andersen, LJ Shimkets, Lotte Søgaard-Andersen, M Christen, M Christen, M Fazli, M Merighi, M Overgaard, M Singer, Mitchell Singer, MR Neunuebel, MV Navarro, N Sudarsan, N Tschowri, NB Caberoy, PD Newell, PV Krasteva, PV Krasteva, R Hengge, R Paul, R Paul, R Tamayo, RP Ryan, RP Ryan, RP Ryan, S Abel, S Steiner, SS Wu, SS Wu, SS Wu, SZ Sultan, T Petters, T Schirmer, TA Ramelot, TM Gronewold, Tobias Petters, U Römling, V Jakovljevic, Volkhard Kaever, W Li, X Fang, Y Li, Y Qi, Z Yang, ZH Chen, ZM Yang   +87 more
core   +3 more sources

The cyclic-di-GMP signaling pathway in the Lyme disease spirochete, [PDF]

, 2014
In nature, the Lyme disease spirochete Borrelia burgdorferi cycles between the unrelated environments of the Ixodes tick vector and mammalian host. In order to survive transmission between hosts, B.
Adams, Adams, Albright, Amikam, Andrade, Armitage, Barends, Barrett, Beier, Benach, Berg, Bian, Blevins, Boardman, Bobrov, Boehm, Boylan, Brisson, Brooks, Brown, Burgdorfer, Burtnick, Caimano, Caimano, Caimano, Carroll, Carroll, Casjens, Chae, Chang, Chang, Charon, Chatterjee, Christen, Christen, Christen, Cotter, Duerig, Dunham-Ems, Fang, Fazli, Fisher, Fraser, Freedman, Fries, Galperin, Galperin, Galperin, Girgis, Goldman, Groshong, Habazettl, HajduÅ¡ek, Hammer, He, He, Hengge, Hickman, Hickman, Hyde, Hyde, Hübner, Jenal, Katona, Kazmierczak, Kim, Ko, Kostick, Krasteva, Kuehn, Kulasekara, Lai, Lane, Lee, Levine, Li, Luo, Maes, Massie, Mather, McCarthy, Merighi, Monds, Moriarty, Motaleb, Motaleb, Nickels, Norman, Ojaimi, Ojaimi, Ostfeld, Ouyang, Ouyang, Ouyang, Ouyang, Pappas, Paul, Paul, Pazy, Pesavento, Pitzer, Pratt, Radolf, Revel, Rogers, Ross, Russell, Ryan, Ryan, Ryan, Ryan, Ryan, Ryjenkov, Ryjenkov, Römling, Römling, Römling, Römling, Samuels, Samuels, Schirmer, Schmidt, Schmidt, Seshu, Silversmith, Smith, Sommerfeldt, Sonenshine, Sonenshine, Stelitano, Stock, Sudarsan, Sultan, Sultan, Sze, Sze, Tal, Tam, Tamayo, Tamayo, Tamayo, Tao, Thomas, Tilly, Tokarz, Trappetti, Tsao, Tuckerman, Tuckerman, Vvedenskaya, Weber, West, Wolfe, Xu, Yang, Yang, Yildiz, Yildiz, Zhang, Zorraquino   +159 more
core   +2 more sources

Role of small colony variants in persistence of Pseudomonas aeruginosa infections in cystic fibrosis lungs [PDF]

, 2015
Jacob G Malone1,21John Innes Centre, Norwich, UK; 2School of Biological Sciences, University of East Anglia, Norwich, UKAbstract: Pseudomonas aeruginosa is an opportunistic pathogen that predominates during the later stages of cystic fibrosis (CF) lung ...
Malone, Jacob
core   +2 more sources

Interaction and Signalling Networks:a report from the fourth 'Young Microbiologists Symposium on Microbe Signalling, Organisation and Pathogenesis' [PDF]

, 2017
At the end of June, over 120 microbiologists from 18 countries gathered in Dundee, Scotland for the fourth edition of the Young Microbiologists Symposium on ‘Microbe Signalling, Organisation and Pathogenesis’.
Clare L. Kirkpatrick, Delphine L. Caly, Jacob G. Malone, Olivier Lesouhaitier, Planamente, Shi-Qi An   +5 more
core   +5 more sources

Cephalosporin-3’-diazeniumdiolate NO-donor prodrug PYRRO-C3D enhances azithromycin susceptibility of non-typeable Haemophilus influenzae biofilms [PDF]

, 2016
The file attached to this record is the author's final peer reviewed version. The Publisher's final version can be found by following the DOI link.Objectives: PYRRO-C3D is a cephalosporin-3-diazeniumdiolate nitric oxide (NO)-donor prodrug designed to ...
Allan, Raymond N., Coles, J., Collins, S. A., Connett, G., Faust, S. N., Feelisch, M., Hall-Stoodley, L., Halladay, G. D., Jackson, C. L., Kelso, M. J., Lucas, J. S. A., Rineh, A., Walker, W. T., Webb, J. S., Yepuri, N. R.   +14 more
core   +2 more sources

Dimerisation induced formation of the active site and the identification of three metal sites in EAL-phosphodiesterases [PDF]

, 2017
The bacterial second messenger cyclic di-3′,5′-guanosine monophosphate (c-di-GMP) is a key regulator of bacterial motility and virulence. As high levels of c-di-GMP are associated with the biofilm lifestyle, c-di-GMP hydrolysing phosphodiesterases (PDEs)
A Deepthi, A Sundriyal, A Tchigvintsev, A Ueda, A Vagin, A Winkler, AD Tischler, AD Tischler, AJ Schmidt, B Huang, BW Holloway, C Chan, C Romier, CD Boyd, CW Phippen, D Balasubramanian, D Bellini, DA D’Argenio, DJ Hosfield, DL Caly, EF Pettersen, F Rao, F Rao, G Kuppuraj, G Minasov, G Winter, G Winter, GL Winsor, GN Murshudov, H Ceri, H Kulasakara, H Zheng, I Ivanov, ID Hay, J Robert-Paganin, JH Merritt, K Syson, K-H Choi, KD Miner, KM Thormann, M Christen, M Valentini, M Vorachit, MD Winn, MVAS Navarro, MY Galperin, N Barraud, O Kirillina, P Aldridge, P Emsley, P Evans, PD Newell, PR Evans, R Donlan, R Paul, R Simm, R Tamayo, RM Keegan, RP Ryan, RP Ryan, RZ Liao, TRM Barends, TT Hoang, U Römling, V Stelitano, VB Chen, W Grzybkowski, W Kabsch, Y Li, Y Qi, Y Wang   +70 more
core   +2 more sources

A two‐component system involving an HD‐GYP domain protein links cell–cell signalling to pathogenicity gene expression in Xanthomonas campestris [PDF]

Molecular Microbiology, 2000
The synthesis of extracellular enzymes and extracellular polysaccharide (EPS) in Xanthomonas campestris pv. campestris (Xcc) is regulated by a cluster of genes called rpf (for regulation of pathogenicity factors). Two of the genes, rpfF and rpfB, have previously been implicated in the synthesis of a diffusible regulatory molecule, DSF.
H, Slater, A, Alvarez-Morales, C E, Barber, M J, Daniels, J M, Dow   +4 more
openaire   +2 more sources

Formation of a complex between HD-GYP, GGDEF and PilZ domain proteins regulates motility in Xanthomonas campestris

Microbiology Research, 2018
RpfG is a member of a class of wide spread bacterial two-component regulators with an HD-GYP cyclic di-GMP phosphodiesterase domain. In the plant pathogen Xanthomonas campestris pv. campestris (Xcc), RpfG together with the sensor kinase RpfC regulates the synthesis of a range of virulence factors as a response to the cell-cell Diffusible Signaling ...
Shi-qi An, Ji-liang Tang
openaire   +2 more sources

An HD domain phosphohydrolase active site tailored for oxetanocin-A biosynthesis [PDF]

, 2016
HD domain phosphohydrolase enzymes are characterized by a conserved set of histidine and aspartate residues that coordinate an active site metallocenter. Despite the important roles these enzymes play in nucleotide metabolism and signal transduction, few
Drennan, Catherine L., Kang, Gyung Hoon, Liu, Hung-wen, Rabb, Jennifer, Zhong, Aoshu   +4 more
core   +1 more source