Analysis of the HD-GYP domain cyclic dimeric GMP phosphodiesterase reveals a role in motility and the enzootic life cycle of Borrelia burgdorferi. [PDF]
Infect Immun, 2011 ABSTRACT HD-GYP domain cyclic dimeric GMP (c-di-GMP) phosphodiesterases are implicated in motility and virulence in bacteria. Borrelia burgdorferi possesses a single set of c-di-GMP-metabolizing enzymes, including a putative HD-GYP domain protein, BB0374.
Sultan SZ +5 more
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c-di-GMP turn-over in Clostridium difficile is controlled by a plethora of diguanylate cyclases and phosphodiesterases. [PDF]
PLoS Genetics, 2011 Clostridium difficile infections have become a major healthcare concern in the last decade during which the emergence of new strains has underscored this bacterium's capacity to cause persistent epidemics.
Eric Bordeleau +3 more
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Screening for Diguanylate Cyclase (DGC) Inhibitors Mitigating Bacterial Biofilm Formation
Frontiers in Chemistry, 2020 The majority of bacteria in the natural environment organize themselves into communal biofilms. Biofilm formation benefits bacteria conferring resistance to harmful molecules (e.g., antibiotics, disinfectants, and host immune factors) and coordinating ...
Kyu Hong Cho +2 more
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Frontiers in Microbiology, 2014 We surveyed the eight putative cyclic-di-GMP-modulating response regulators (RRs) in Desulfovibrio vulgaris Hildenborough that are predicted to function via two-component signaling.
Lara eRajeev +10 more
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Molecular Plant-Microbe Interactions, 2020 The degenerate GGDEF/EAL domain protein Filp was previously shown to function as a cyclic di-GMP (c-di-GMP) signal receptor through its specific interaction with an atypical PilZ domain protein PilZX3 (formerly PXO_02715) and that this interaction is ...
Muhammad Umar Shahbaz +7 more
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Genetic mapping of loci associated with yield and their components in black common bean (Phaseolus vulgaris L.). [PDF]
Plant GenomeAbstract The increase in world population linked to climate change leads to the need to develop more productive and more adapted cultivars of food species. Quantitative trait loci (QTLs) mapping is a useful tool although, interaction between genotype and the environment is still a challenge.
Reche DL +6 more
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Retraction for Ryan et al., Cell-cell signaling in Xanthomonas campestris involves an HD-GYP domain protein that functions in cyclic di-GMP turnover. [PDF]
Proc Natl Acad Sci U S A, 2017 europepmc +4 more sources
To Move or Not to Move: When and How Bacteria Suppress Flagellar Motility. [PDF]
Mol MicrobiolMotility cessation in bacteria is a key regulatory strategy that provides multiple survival advantages including enhanced community cooperation, niche adaptation and evasion of host immune responses. This process is controlled by associated mechanisms such as post‐translational modifications and second messenger signalling that stabilise non‐motile ...
Mohaghegh F, Scadden J, Baker MAB.
europepmc +2 more sources
Frontiers in Microbiology, 2019 Xanthomonas oryzae pv. oryzae (Xoo) causes bacterial leaf blight of rice, one of the most devastating bacterial diseases of this staple crop worldwide. Xoo produces a range of virulence-related factors to facilitate its pathogenesis in rice, however, the
Fenghuan Yang +5 more
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Proteomic Analysis of Three Independent Series of Sequential Cystic Fibrosis Strains in an International Pseudomonas aeruginosa Reference Panel Indicates Positive Selection in Late Infection Strains. [PDF]
MicrobiologyopenComparison of proteomes from three series of sequential Pseudomonas aeruginosa isolates from people with cystic fibrosis identified eleven proteins with increased abundance in at least one late isolate per patient. Three proteins were increased in all five late isolates, and the probability of this occurring by chance is 5.06 × 10−53, indicating strong
Drabinska J +3 more
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