Discovery of Novel c-di-GMP-Related Genes in Leptospira interrogans
PathogensCyclic di-GMP (bis-(3′→5′) cyclic dimeric guanosine monophosphate) is a ubiquitous bacterial second messenger that regulates a wide range of cellular processes, including biofilm formation, motility, virulence, and environmental adaptation.
Anielle Salviano de Almeida Ferrari +9 more
doaj +1 more source
High-resolution transcriptional analysis of the regulatory influence of cell-to-cell signalling reveals novel genes that contribute to Xanthomonas phytopathogenesis [PDF]
, 2013 The bacterium Xanthomonas campestris is an economically important pathogen of many crop species and a model for the study of bacterial phytopathogenesis.
An, Shi-Qi +10 more
core +3 more sources
Cyclic di-GMP: second messenger extraordinaire [PDF]
, 2017 Cyclic dinucleotides (CDNs) are highly versatile signalling molecules that control various important biological processes in bacteria. The best-studied example is cyclic di-GMP (c-di-GMP).
Jenal, Urs +2 more
core +1 more source
The Diverse Roles of the Histone‐Like Nucleoid Structuring (H‐NS) Protein in Vibrio parahaemolyticus
Genetics Research , Volume 2026, Issue 1, 2026.The histone‐like nucleoid structuring (H‐NS) protein is a global transcriptional regulator critical for bacterial genome organization and gene expression. In Vibrio parahaemolyticus, H‐NS represses virulence factors such as thermostable direct hemolysin (TDH), type III secretion systems (T3SS1/T3SS2), and type VI secretion systems (T6SS1/T6SS2).
Hao Tang, Yiquan Zhang, Richa Sharma
wiley +1 more source
, 2016 The cyclic di-GMP (c-di-GMP) second messenger represents a signaling system that regulates many bacterial behaviors and is of key importance for driving the lifestyle switch between motile loner cells and biofilm formers.
Filloux, A, Valentini, M
core +2 more sources
Finally! The structural secrets of a
Molecular Microbiology, 2013 SummaryThe major sessility‐motility lifestyle change and additional fundamental aspects of bacterial physiology, behaviour and morphology are regulated by the secondary messenger cyclic di‐GMP (c‐di‐GMP). Although the c‐di‐GMP metabolizing enzymes and many receptors have been readily characterized upon discovery, the HD‐GYP domain c‐di‐GMP ...
Edvard, Wigren +2 more
openaire +2 more sources
Farmland abandonment and season drive scavenging dynamics in livestock‐rewilded landscapes
Ecological Applications, Volume 35, Issue 8, December 2025.Abstract Farmland abandonment occurs commonly across European mountain regions, which causes triggering of habitat encroachment through shrub regeneration and natural afforestation. However, its impact on vertebrate scavenger communities and ecological processes, such as the removal of small carcasses remains poorly understood.
Rocío R. Daza +2 more
wiley +1 more source
Diffusible Signal Factor (DSF)-dependent quorum sensing in pathogenic bacteria and its exploitation for disease control [PDF]
, 2016 Cell-to-cell signals of the Diffusible Signal Factor (DSF) family are cis-2-unsaturated fatty acids of differing chain length and branching pattern. DSF signalling has been described in diverse bacteria to include plant and human pathogens where it acts ...
Dow, J. Maxwell
core +1 more source
The HD‐GYP domain of RpfG mediates a direct linkage between the Rpf quorum‐sensing pathway and a subset of diguanylate cyclase proteins in the phytopathogen Xanthomonas axonopodis pv citri [PDF]
Molecular Microbiology, 2006 SummaryBacteria use extracellular levels of small diffusible autoinducers to estimate local cell‐density (quorum‐sensing) and to regulate complex physiological processes. The quorum‐sensing signal transduction pathway of Xanthomonas spp. phytopathogens has special features that distinguish it from that of other pathogens. This pathway consists of RpfF,
Maxuel O, Andrade +6 more
openaire +2 more sources
Astrocyte Lipid Droplet Dynamics Orchestrate Neurological Disorders and Therapeutic Horizons
Small Science, Volume 5, Issue 9, September 2025.This review examines astrocyte lipid droplet (LD) metabolism in neurological disorders, including Alzheimer's disease, stroke, epilepsy, and glioma. It analyzes regulatory mechanisms governing LD formation, transport, and degradation in astrocytes, highlighting their potential as biomarkers and therapeutic targets through integrative multiomics ...
Jiani Zhong +4 more
wiley +1 more source