Results 41 to 50 of about 3,215 (191)

Dissecting HDAC3-mediated tumor progression [PDF]

Cancer Biology & Therapy, 2008
Commentary to:HDAC3 impacts multiple oncogenic pathways in colon cancer cells with effects on Wnt and vitamin D signalingCassandra A. Godman, Rashmi Joshi, Brendan R. Tierney, Emily Greenspan, Theodore P. Rasmussen, Hsin-wei Wang, Dong-Guk Shin, Daniel W.
openaire   +2 more sources

The Bdnf and Npas4 genes are targets of HDAC3-mediated transcriptional repression

BMC Neuroscience, 2019
Background Histone deacetylase-3 (HDAC3) promotes neurodegeneration in various cell culture and in vivo models of neurodegeneration but the mechanism by which HDAC3 exerts neurotoxicity is not known.
Anto Sam Crosslee Louis Sam Titus, Dharmendra Sharma, Min Soo Kim, Santosh R. D’Mello   +3 more
doaj   +1 more source

20200107 LC3 HDAC3 manuscript_sup.ppt

, 2020
The potential role of LC3B and HDAC3 in hepatic lipid accumulation in both in vivo and in vitro ...
Yuan-Xiang Pan (8025575)
core   +1 more source

SERPINA3-ANKRD11-HDAC3 pathway induced aromatase inhibitor resistance in breast cancer can be reversed by HDAC3 inhibition

Communications Biology, 2023
AbstractEndocrine resistance is a major challenge for breast cancer therapy. To identify the genes pivotal for endocrine-resistance progression, we screened five datasets and found 7 commonly dysregulated genes in endocrine-resistant breast cancer cells.
Jing Zhou, Mengdi Zhu, Qi Wang, Yiyuan Deng, Nianqiu Liu, Yujie Liu, Qiang Liu   +6 more
openaire   +3 more sources

HDAC3 deacetylates and activates PGK1.

, 2015
(A, B) PGK1 interacts with HDAC3. Flag-tagged PGK1 was overexpressed in HEK293T cells together with the individual HA-tagged HDAC as indicated. PGK1 protein was purified by IP with Flag beads, following western blot to detect HDACs with a human influenza
Dan Ye (180080), Tengfei Zhang (794004), Leilei Chen (214607), Lixia Liu (447585), Yukun Xia (794008), Yue Xiong (794009), Yi Wang (32470), Kun-Liang Guan (794010), Huaipeng Lin (794006), Lisha Zhou (794007), Yiping Wang (1484218), Chen Yang (207381), Shiwen Wang (132242), Xiufei Chen (794005), Bowen Jiang (794003)   +14 more
core   +1 more source

HDAC3

, 2023
The histone deacetylase HDAC3 is associated with the NCoR/SMRT co-repressor complex, and its canonical function is in transcriptional repression, but it can also activate transcription.
Lei Xu, Sergey Belikov, Wu, Hongmei, Xuewen Liu, Magda Bienko, Bienko, Magda, Shilkova, Olga,, Mattias Mannervik, Olga Shilkova, Tang, Min,, Liu, Xuewen, Belikov, Sergey,, Xu, Lei, Mannervik, Mattias,, Regadas, Isabel,, Hongmei Wu, Min Tang, Isabel Regadas, Erik Wernersson, Wernersson, Erik, Liu, X, Regadas, Isabel, Mannervik, Mattias, Tang, Min, Belikov, Sergey, Wernersson, E,, Xu, L, Tang, M, Mannervik, M, Shilkova, O,, Regadas, I, Belikov, S, Wu, H, Bienko, M,, Shilkova, Olga   +34 more
core   +1 more source

HDAC3 acts as a negative regulator of angiogenesis

BMB Reports, 2014
Histone deacetylase-3 (HDAC3) is involved in cellular proliferation, apoptosis and transcriptional repression. However, the role of HDAC3 in angiogenesis remains unknown. HDAC3 negatively regulated the expression of angiogenic factors, such as VEGF and plasminogen activator inhibitor-1 (PAI-1). HDAC3 showed binding to promoter sequences of PAI-1. HDAC3
Park, Deokbum, Park, Hyunmi, Kim, Youngmi, Kim, Hyuna, Jeoung, Dooil   +4 more
openaire   +4 more sources

PINK1 positively regulates HDAC3 to suppress dopaminergic neuronal cell death

, 2015
Deciphering the molecular basis of neuronal cell death is a central issue in the etiology of neurodegenerative diseases, such as Parkinson's and Alzheimer's. Dysregulation of p53 levels has been implicated in neuronal apoptosis.
박수연, 최효경, 강희범, 윤호근   +3 more
core   +2 more sources

Histone deacetylase 3 facilitates TNFα-mediated NF-κB activation through suppressing CTSB induced RIP1 degradation and is required for host defense against bacterial infection

Cell & Bioscience, 2022
Background As important enzymes regulating acetylation, histone deacetylases (HDACs) participate in a series of cell physiological process. However, the mechanisms responsible for individual HDAC family members in regulating innate immunity remained to ...
Liping Yang, Shengchuan Chen, Jingyan Xia, Ying Zhou, Linan Peng, Huimin Fan, Yu Han, Lihua Duan, Genhong Cheng, Heng Yang, Feng Xu   +10 more
doaj   +1 more source

Wharton’s jelly-mesenchymal stem cells alleviate atopic dermatitis by regulating TXNIP/NLRP3 and HDAC3/TGF-β1 signaling pathway in mice

Romanian Journal of Laboratory Medicine
Atopic dermatitis (AD) is a chronic immune and inflammatory dermatologic disease. Preclinical and clinical studies have indicated that stem cell transplantation is considered an alternative treatment option for ameliorating the symptoms of AD.
Wu ZhengPing, Cai JiaYi, Li Ning, Han Di, Liu Hong, Mai XinWen, Chen SenYu, Liao ManYu, Zhang Peng, Liu Chi-Ming   +9 more
doaj   +1 more source