Results 71 to 80 of about 6,066,735 (160)

Thermotolerance and plasticity of camel somatic cells exposed to acute and chronic heat stress

Journal of Advanced Research, 2020
The Arabian camel is the largest known mammal that can survive in severe hot climatic conditions. We provide the molecular explanation for the thermotolerance of camel granulosa somatic cells after exposure to 45 °C for 2 (acute heat shock) or 20 h ...
Islam M. Saadeldin, Ayman Abdel-Aziz Swelum, Mona Elsafadi, Amer Mahmood, Aya Osama, Hassan Shikshaky, Musaad Alfayez, Abdullah N. Alowaimer, Sameh Magdeldin   +8 more
doaj   +1 more source

Regulation Between HSF1 Isoforms and HSPs Contributes to the Variation in Thermal Tolerance Between Two Oyster Congeners

Frontiers in Genetics, 2020
Heat shock transcription factor 1 (HSF1) plays an important role in regulating heat shock, which can activate heat shock proteins (HSPs). HSPs can protect organisms from thermal stress. Oysters in the intertidal zone can tolerate thermal stress.
Youli Liu, Youli Liu, Li Li, Li Li, Li Li, Li Li, Haigang Qi, Haigang Qi, Haigang Qi, Haigang Qi, Huayong Que, Huayong Que, Huayong Que, Huayong Que, Wei Wang, Wei Wang, Wei Wang, Wei Wang, Guofan Zhang, Guofan Zhang, Guofan Zhang, Guofan Zhang   +21 more
doaj   +1 more source

Heat Shock Related Protein Expression in Abdominal Testes of Asian Elephant (Elephas maximus)

Animals
The abdominal testes of Asian elephants show normal spermatogenesis. Heat shock in cryptorchid testes elevates heat shock factor (HSF) expression, leading to germ cell apoptosis, while increased heat shock proteins (HSPs) levels provide protection.
Yoko Sato, Theerawat Tharasanit, Chatchote Thitaram, Chaleamchat Somgird, Sittidet Mahasawangkul, Nikorn Thongtip, Kaywalee Chatdarong, Narong Tiptanavattana, Masayasu Taniguchi, Takeshige Otoi, Mongkol Techakumphu   +10 more
doaj   +1 more source

Heat shock protein-90-alpha, a prolactin-STAT5 target gene identified in breast cancer cells, is involved in apoptosis regulation [PDF]

, 2008
Introduction The prolactin-Janus-kinase-2-signal transducer and activator of transcription-5 (JAK2-STAT5) pathway is essential for the development and functional differentiation of the mammary gland.
Liu, R., Bork, Peer, Shemanko, Carrie S., Shemanko, C., Liu, Ruixuan, Pfitzner, Edith, Schultz, J., Christine T Parusel, Jörg Schultz, Groner, Bernd, Parusel, Christine T., Bork, P., Boecher, N., Perotti, Christian, Christian Perotti, Ruixuan Liu, Carrie S Shemanko, Pfitzner, E., Groner, B., Schultz, Jörg, Bernd Groner, Böcher, Nadine, Nadine Böcher, Perotti, C., Peer Bork, Edith Pfitzner, Parusel, C.   +26 more
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A novel plant E3 ligase stabilizes Escherichia coli heat shock factor σ32

Scientific Reports, 2017
The heat shock response is crucial for organisms against heat-damaged proteins and maintaining homeostasis at a high temperature. Heterologous expression of eukaryotic molecular chaperones protects Escherichia coli from heat stress.
Yulong Niu, Xibing Xu, Chengcheng Liu, Tao Wang, Ke Liang, Jianmei Wang, Zhibin Liu, Xufeng Li, Yi Yang   +8 more
doaj   +1 more source

Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels

Cancer Biology & Medicine, 2019
Objective Heat shock factor 1 (HSF1), a transcriptional regulator of heat shock proteins (HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1 inhibitors have been identified so far.Methods The mRNA and protein levels of HSF1 ...
Na Li, Ting Wang, Zongmeng Li, Xiaoli Ye, Bo Deng, Shu Zhuo, Pengle Yao, Mengmei Yang, Hong Mei, Xiaofang Chen, Tengfei Zhu, Shiting Chen, Hui Wang, Jiming Wang, Yingying Le   +14 more
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Molecular mechanisms of heat shock proteins in distinct diseases [PDF]

, 2023
Heat shock proteins (HSPs) modulate the molecular mechanics of cells and cellular systems. Properly folded proteins are required for cellular processes and organisms use molecular mechanics to keep substrate proteins in their native state.
Abay, Cansu, Tutar, Merve, Niyazov, Laziz, Yürekli, Nazlıcan, Okat, Zehra, Tutar, Yusuf, Gök Yurttaş, Asiye, Açıkalın Coşkun, Kübra, Uçar Çifçi, Kezban, Al, Mervenur, Sağır, Fatma   +10 more
core  

Comparative Transcriptomic Analysis Reveals the Involvement of Auxin Signaling in the Heat Tolerance of Pakchoi under High-Temperature Stress

Agronomy
Pakchoi is a kind of nonheading Chinese cabbage being widely cultivated not only in China but also all over Asia. High temperature is a major limiting factor influencing the yield and quality of pakchoi, while the mechanism of pakchoi dealing with high ...
Bing Yang, Yaosong Chen, Xiaofeng Li, Lu Gao, Liming Miao, Yishan Song, Dingyu Zhang, Hongfang Zhu   +7 more
doaj   +1 more source

MED26 facilitates Mediator-Pol II complex assembly and promotes nuclear stress body formation during heat stress

iScience
Summary: Cells adapt to environmental stress by reprogramming gene expression. During heat stress, the transcription factor heat shock factor 1 (HSF1) translocates into the nucleus and activates heat shock-responsive loci, including the long non-coding ...
Kexin Li, Kazuki Furugori, Hidefumi Suzuki, Ryota Abe, Shun Sawatsubashi, Nanami Yasui, Yoko Ike, Keiko Horiuchi, Hidehisa Takahashi   +8 more
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Heat Shock Factor 5 Is Essential for Spermatogenesis in Zebrafish

Cell Reports, 2018
Summary: Heat shock factors (Hsfs) are transcription factors that regulate responses to heat shock and other environmental stimuli. Four heat shock factors (Hsf1-4) have been characterized from vertebrates to date.
Jolly M. Saju, Mohammad Sorowar Hossain, Woei Chang Liew, Ajay Pradhan, Natascha May Thevasagayam, Lydia Shun En Tan, Amit Anand, Per-Erik Olsson, László Orbán   +8 more
doaj   +1 more source