Results 71 to 80 of about 948,615 (346)
Hsp56 protein and mRNA distribution in normal and stressed P.lividus embryos [PDF]
, 2008 It was previously demonstrated that Paracentrotus lividus Hsp56 mitochondrial chaperonin is con- stitutively expressed during development, that it increases after heat-shock and cadmium treatment, and that it has a speci\ufb01c territorial distribution,
Agnello, M. +5 more
core +1 more source
Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system
FEBS Open Bio, EarlyView.An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková +3 more
wiley +1 more source
Heat Shock Factor 2 Protects against Proteotoxicity by Maintaining Cell-Cell Adhesion
Cell Reports, 2020 Summary: Maintenance of protein homeostasis, through inducible expression of molecular chaperones, is essential for cell survival under protein-damaging conditions.
Jenny Joutsen +10 more
doaj +1 more source
A Novel Approach of Virotherapy Based Hsf-1 Shrna in Cancer Eradication [PDF]
, 2013 Cancer is the second leading cause of death worldwide with continues rise mortality rate. Current cancer treatment modalities are still ineffective and associated with many side effects leading to robust research to find new specific target therapy. Heat
Supadmanaba, I. G. (I) +1 more
core
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Salicylate Triggers Heat Shock Factor Differently than Heat [PDF]
Journal of Biological Chemistry, 1995 Sodium salicylate has the unusual property of partially inducing the human heat shock response (Jurivich, D. A., Sistonen, L., Kroes, R., and Morimoto, R. I. (1992) Science 255, 1243-1245). Salicylate induces the DNA binding state of the human heat shock transcription factor (HSF), but this is insufficient to elevate heat shock gene expression. Because
D A, Jurivich +3 more
openaire +2 more sources
PLoS ONE, 2014 The rapid increase in heat shock proteins upon exposure to damaging stresses and during plant development related to desiccation events reveal their dual importance in plant development and stress tolerance.
P. S. Reddy +7 more
semanticscholar +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
Cooperative Binding of Heat Shock Factor to the Yeast \u3ci\u3eHSP82\u3c/i\u3e Promoter In Vivo and In Vitro [PDF]
, 1999 revious work has shown that heat shock factor (HSF) plays a central role in remodeling the chromatin structure of the yeastHSP82 promoter via constitutive interactions with its high-affinity binding site, heat shock element 1 (HSE1).
Erkine, Alexander M. +3 more
core +1 more source
Heat shock protein 10 inhibits lipopolysaccharide-induced inflammatory mediator production [PDF]
, 2005 Heat shock protein 10 (Hsp10) and heat shock protein 160 (Hsp60) were originally described as essential mitochondrial proteins involved in protein folding.
Banovic, T +9 more
core +1 more source