Results 81 to 90 of about 202,314 (262)

Heat Shock Factor 5 Is Essential for Spermatogenesis in Zebrafish

open access: yesCell Reports, 2018
Summary: Heat shock factors (Hsfs) are transcription factors that regulate responses to heat shock and other environmental stimuli. Four heat shock factors (Hsf1-4) have been characterized from vertebrates to date.
Jolly M. Saju   +8 more
doaj   +1 more source

Solution‐Processed Mn‐Doped 2d Perovskite Wavelength Shifters for Noble‐Liquid Photon Detection

open access: yesAdvanced Functional Materials, EarlyView.
Solution‐processed Mn2+‐doped PEA2PbBr4 two‐dimensional perovskite films are demonstrated as large‐area wavelength shifters for noble‐liquid photon detectors. Mn2+ incorporation introduces a broad emission band at ∼620 nm with a large Stokes shift, suppressing self‐absorption and matching SiPM sensitivity.
Elisabetta Colantoni   +6 more
wiley   +1 more source

Dorsomorphin induces cancer cell apoptosis and sensitizes cancer cells to HSP90 and proteasome inhibitors by reducing nuclear heat shock factor 1 levels

open access: yesCancer Biology & Medicine, 2019
Objective Heat shock factor 1 (HSF1), a transcriptional regulator of heat shock proteins (HSPs), is an attractive therapeutic target for cancer. However, only a few HSF1 inhibitors have been identified so far.Methods The mRNA and protein levels of HSF1 ...
Na Li   +14 more
doaj   +1 more source

Sky‐Directional Radiative Cooling Meta‐Films for Daylighting Windows

open access: yesAdvanced Functional Materials, EarlyView.
A geometry‐mediated microprism meta‐film enables transparent, sky‐directional radiative cooling for daylighting windows. By decoupling control of visible transmittance from mid‐infrared emissivity, ground‐emitted heat absorption is suppressed while skyward heat dissipation is enhanced.
Seung‐Ah Yu   +7 more
wiley   +1 more source

Comparative Transcriptomic Analysis Reveals the Involvement of Auxin Signaling in the Heat Tolerance of Pakchoi under High-Temperature Stress

open access: yesAgronomy
Pakchoi is a kind of nonheading Chinese cabbage being widely cultivated not only in China but also all over Asia. High temperature is a major limiting factor influencing the yield and quality of pakchoi, while the mechanism of pakchoi dealing with high ...
Bing Yang   +7 more
doaj   +1 more source

A novel plant E3 ligase stabilizes Escherichia coli heat shock factor σ32

open access: yesScientific Reports, 2017
The heat shock response is crucial for organisms against heat-damaged proteins and maintaining homeostasis at a high temperature. Heterologous expression of eukaryotic molecular chaperones protects Escherichia coli from heat stress.
Yulong Niu   +8 more
doaj   +1 more source

Mechanical Programming of PEGDA‐β‐CD Polyrotaxane‐Based Hydrogels via Host–Guest Molecular Recognition

open access: yesAdvanced Functional Materials, EarlyView.
A mechanically programmable hydrogel for tissue engineering is developed by modulating the molecular threading density of poly(ethylene glycol) diacrylate‐β‐cyclodextrin (PEGDA‐β‐CD) polyrotaxane and combining it with β‐CD‐modified gelatin. The polyrotaxane‐guided transition from disordered pores to laminar microstructures enables precise tuning ...
Shiyi Chen   +10 more
wiley   +1 more source

Dynamic Loading Regulates Meniscus‐Like Matrix Production in Human Mesenchymal Stromal Cell‐Seeded PET Scaffolds

open access: yesAdvanced Healthcare Materials, EarlyView.
Dynamic compression enhances mesenchymal stromal cell proliferation in nonwoven PET scaffolds under chondrogenic differentiation conditions and triggers mechanosensitive transcriptional programs associated with extracellular matrix remodeling. These findings highlight the potential of mechanically stimulated PET scaffolds as a promising platform for ...
Graciosa Quelhas Teixeira   +8 more
wiley   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

open access: yesAdvanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky   +12 more
wiley   +1 more source

Neuromorphic Electronics for Intelligence Everywhere: Emerging Devices, Flexible Platforms, and Scalable System Architectures

open access: yesAdvanced Materials, EarlyView.
The perspective presents an integrated view of neuromorphic technologies, from device physics to real‐time applicability, while highlighting the necessity of full‐stack co‐optimization. By outlining practical hardware‐level strategies to exploit device behavior and mitigate non‐idealities, it shows pathways for building efficient, scalable, and ...
Kapil Bhardwaj   +8 more
wiley   +1 more source

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