Results 61 to 70 of about 6,066,735 (160)

Diversification of the Caenorhabditis heat shock response by Helitron transposable elements

eLife, 2019
Heat Shock Factor 1 (HSF-1) is a key regulator of the heat shock response (HSR). Upon heat shock, HSF-1 binds well-conserved motifs, called Heat Shock Elements (HSEs), and drives expression of genes important for cellular protection during this stress ...
Jacob M Garrigues, Brian V Tsu, Matthew D Daugherty, Amy E Pasquinelli   +3 more
doaj   +1 more source

Reprogramming of the transcriptome after heat stress mediates heat hormesis in Caenorhabditis elegans

Nature Communications, 2023
Transient stress experiences not only trigger acute stress responses, but can also have long-lasting effects on cellular functions. In Caenorhabditis elegans, a brief exposure to heat shock during early adulthood extends lifespan and improves stress ...
Fan Xu, Ruoyao Li, Erika D. von Gromoff, Friedel Drepper, Bettina Knapp, Bettina Warscheid, Ralf Baumeister, Wenjing Qi   +7 more
doaj   +1 more source

Molecular Mechanisms of Heat Shock Factors in Cancer

Cells, 2020
Malignant transformation is accompanied by alterations in the key cellular pathways that regulate development, metabolism, proliferation and motility as well as stress resilience. The members of the transcription factor family, called heat shock factors (
Mikael Christer Puustinen, Lea Sistonen
doaj   +1 more source

Cloning and characterisation of heat shock and wound-induced genes in pea (pisum sativum L.) [PDF]

, 1997
Plant productivity in many regions of the world is limited primarily as a result of environmental stresses. High temperature and wounding caused by pest and pathogen infection are among the main factors accounting for unpredictable and often severe yield
Dhankher, Om Parkash
core  

The Structural Deciphering of the α3 Helix Within ZmHsfA2’S DNA-Binding Domain for the Recognition of Heat Shock Elements in Maize

Plants
Heat shock transcription factor (Hsf) plays a pivotal role in regulating plant growth, development, and stress responses. Hsf activates or represses target gene transcription by binding to the heat shock element (HSE) of downstream genes.
Yantao Wang, Zhenyu Ma, Guoliang Li, Xiangzhao Meng, Shuonan Duan, Zihui Liu, Min Zhao, Xiulin Guo, Huaning Zhang   +8 more
doaj   +1 more source

Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

Nature Communications, 2016
The transcription factor Hsf1 and the molecular chaperone Hsp90 modulate the heat shock response in the pathogen Candida albicans. Here, Leach et al. reveal a complex interplay between the two factors that regulates the expression of genes involved in ...
Michelle D. Leach, Rhys A. Farrer, Kaeling Tan, Zhengqiang Miao, Louise A. Walker, Christina A. Cuomo, Robert T. Wheeler, Alistair J. P. Brown, Koon Ho Wong, Leah E. Cowen   +9 more
doaj   +1 more source

Non-specific protein modifications by a phytochemical induce heat shock response for self-defense. [PDF]

PLoS ONE, 2013
Accumulated evidence shows that some phytochemicals provide beneficial effects for human health. Recently, a number of mechanistic studies have revealed that direct interactions between phytochemicals and functional proteins play significant roles in ...
Kohta Ohnishi, Shinya Ohkura, Erina Nakahata, Akari Ishisaka, Yoshichika Kawai, Junji Terao, Taiki Mori, Takeshi Ishii, Tsutomu Nakayama, Noriyuki Kioka, Shinya Matsumoto, Yasutaka Ikeda, Minoru Akiyama, Kazuhiro Irie, Akira Murakami   +14 more
doaj   +1 more source

Stress-Induced PARP Activation Mediates Recruitment of Drosophila Mi-2 to Promote Heat Shock Gene Expression [PDF]

, 2011
Eukaryotic cells respond to genomic and environmental stresses, such as DNA damage and heat shock (HS), with the synthesis of poly-ADP-ribose] (PAR) at specific chromatin regions, such as DNA breaks or HS genes, by PAR polymerases (PARP). Little is known
Renate Renkawitz-Pohl, Hassler Markus, Murawska, Magdalena, Ladurner Andreas, Brehm Alexander, Andreas Ladurner, Renkawitz-Pohl, Renate, Brehm, Alexander, Ladurner, Andreas, Magdalena Murawska, Murawska Magdalena, Markus Hassler, Hassler, Markus, Alexander Brehm, Renkawitz-Pohl Renate   +14 more
core   +2 more sources

The Safe Recipient of SSC Transplantation Prepared by Heat Shock With Busulfan Treatment in Mice

Cell Transplantation, 2018
Safety is the chief consideration in recipient preparation of spermatogonial stem cell (SSC) transplantation in mammals, especially humans. In this study, we compared the safety of the SSC transplantation recipients that were prepared both by testes heat
Wenzhi Ma, Jia Wang, Weijun Gao, Hua Jia
doaj   +1 more source

Investigation on wedge shock wave control by surface MHD actuation

AIP Advances, 2020
To study the effect of magnetohydrodynamic actuation on wedge shock waves under hypersonic flow, experiments were conducted in a Mach 7 hypersonic shock tunnel.
Geng Gong, Yiwen Li, Yutian Wang, Peng Kuang   +3 more
doaj   +1 more source