Results 11 to 20 of about 62,795 (214)
Gravitational hedgehog, stringy hedgehog and stringy sphere [PDF]
Journal of High Energy Physics, 2003 11 ...
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The Hedgehog Hold on Homeostasis [PDF]
Cell Stem Cell, 2015 The adult lung is largely quiescent, with airway epithelia turning over slowly. Peng et al. (2015) describe a key role for the Hedgehog pathway in actively maintaining this quiescence, a surprising turn of events given the pathway's established mitogenic role, and they show that Hedgehog pathway attenuation is required for proliferative regeneration.
Christian W. Siebel, Ciara Metcalfe
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Aging, 2015 The Hedgehog (Hh) signal transduction pathway has been discovered as a central regulator of embryonic development, tissue maintenance and repair [1]. Moreover, several recent evidences have highlighted its key function in tumorigenesis [2]. In some familial cancers, such as basal cell carcinoma and medulloblastoma, Hh pathway activation represents the ...
Laukkanen M, Gutkind J, Castellone M
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Molecular Oncology, EarlyView.This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani +14 more
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Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
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Advanced Biology, EarlyView.The manuscript examines preclinical murine and human models to study polycystic ovary syndrome (PCOS), delving into the cellular and molecular mechanisms underlying altered ovarian follicular dynamics. It explores the cellular interactions involved in normal and PCOS ovaries and outlines the current and novel strategies in the search for preclinical ...
Arturo Bevilacqua +5 more
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Hepatology Communications, EarlyView., 2022 Abstract Hepatocellular adenomas (HCAs) are benign liver tumors associated with bleeding or malignant transformation. Data on the indication for surgery are scarce. We analyzed indications and outcome of patients operated for HCAs < 50 mm compared to HCAs ≥ 50 mm. Changes in final postoperative diagnosis were assessed.
Martijn P. D. Haring +70 more
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Conformal capacity of hedgehogs
Conformal Geometry and Dynamics of the American Mathematical Society, 2023 We discuss problems concerning the conformal condenser capacity of “hedgehogs”, which are compact sets E E in the unit disk D = { z : | z | > 1 } \mathbb {D}=\{z:\,|z|>1\} consisting of
Betsakos Dimitrios +2 more
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Recent Applications of Mesoporous Silica Nanoparticles in Gene Therapy
Advanced Healthcare Materials, EarlyView.The review summarizes the synthesis of mesoporous silica nanoparticles (MSNs) with modifiable surface properties, functionalization strategies, mechanism of therapeutic payload release, and current applications in gene therapy, focusing on their capabilities in the targeted delivery of therapeutic nucleic acids, CRISPR‐Cas systems, and other genetic ...
Tamanna Binte Huq +4 more
wiley +1 more source
Advanced Sensor Research, EarlyView.Fast response, zero‐power, text or image sensors utilizing light transmission or reflection, and no unfavorable color change judgments, are fabricated using printed nematic liquid crystals patterned on reactive alignment layers, permit ppt‐ to ppb‐level sensitivity, and were field‐tested with active firefighters.
Ryan A. Williams +9 more
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