Results 11 to 20 of about 161,537 (288)

Hedgehogs as Amplifying Hosts of Severe Fever with Thrombocytopenia Syndrome Virus, China

Emerging Infectious Diseases, 2022
Severe fever with thrombocytopenia syndrome virus (SFTSV) is a tickborne bandavirus mainly transmitted by Haemaphysalis longicornis ticks in East Asia, mostly in rural areas.
Chaoyue Zhao, Xing Zhang, Xiaoxi Si, Ling Ye, Kevin Lawrence, Yajun Lu, Chunhong Du, Haidong Xu, Qian Yang, Qianfeng Xia, Guoxiang Yu, Wei Xu, Fei Yuan, Junfeng Hao, Jia-Fu Jiang, Aihua Zheng   +15 more
doaj   +1 more source

Hedgehog signalling [PDF]

Development, 2016
The Hedgehog (Hh) signalling pathway is one of the key regulators of metazoan development. Hh proteins have been shown to play roles in many developmental processes and have become paradigms for classical morphogens. Dysfunction of the Hh pathway underlies a number of human developmental abnormalities and diseases, making it an important therapeutic ...
Lee, Raymond Teck Ho, Zhao, Zhonghua, Ingham, Philip William   +2 more
openaire   +3 more sources

Drosophila hedgehog signaling range and robustness depend on direct and sustained heparan sulfate interactions

Frontiers in Molecular Biosciences, 2023
Morphogens determine cellular differentiation in many developing tissues in a concentration dependent manner. As a central model for gradient formation during animal development, Hedgehog (Hh) morphogens spread away from their source to direct growth and
Dominique Manikowski, Georg Steffes, Jurij Froese, Sebastian Exner, Kristina Ehring, Fabian Gude, Daniele Di Iorio, Seraphine V. Wegner, Kay Grobe   +8 more
doaj   +1 more source

Morphological and histological study of the third eyelid in hedgehogs

Veterinary Medicine and Science, 2023
Background The third eyelid in animals plays an important role in maintaining eye health. Like other organs of the body, the third eyelid can be afflicted with minor or deep injuries, inflammations or even tumours in different species.
Erfan Shakibapour, Mohammadreza Paryani
doaj   +1 more source

Hedgehog Signalling in Androgen Independent Prostate Cancer [PDF]

, 2008
Objectives: Androgen-deprivation therapy effectively shrinks hormone-naïve prostate cancer, both in the prostate and at sites of distant metastasis.
Bisson, Isabelle, Ktori, Elena, McFaul, Siobhan, Oliver, R. Tim D, Price, Anna M., Prowse, David M., Purkis, Patricia E., Shaw, Greg   +7 more
core   +1 more source

Soluble Heparin and Heparan Sulfate Glycosaminoglycans Interfere with Sonic Hedgehog Solubilization and Receptor Binding

Molecules, 2019
Sonic hedgehog (Shh) signaling plays a tumor-promoting role in many epithelial cancers. Cancer cells produce soluble a Shh that signals to distant stromal cells that express the receptor Patched (Ptc).
Dominique Manikowski, Petra Jakobs, Hamodah Jboor, Kay Grobe   +3 more
doaj   +1 more source

Twist transition of nematic hyperbolic hedgehogs [PDF]

, 2014
Stability of an idealized hyperbolic hedgehog in a nematic liquid crystal against a twist transition is investigated by extending the methodology of Rüdinger and Stark [Liq. Cryst.
Fukuda, J-I, James, R
core   +1 more source

Hedgehog pathway mutations drive oncogenic transformation in high-risk T-cell acute lymphoblastic leukemia. [PDF]

, 2018
The role of Hedgehog signaling in normal and malignant T-cell development is controversial. Recently, Hedgehog pathway mutations have been described in T-ALL, but whether mutational activation of Hedgehog signaling drives T-cell transformation is unknown,
A Dagklis, A Dagklis, A El Andaloussi, A Gutierrez, A Sekulic, AA Ferrando, AE Place, AK Fielding, AL Furmanski, AM Kenney, C Reynolds, CH Pui, CJ Neumann, DD Hoff Von, DI Marks, DM Stone, DV Catenacci, E Drakopoulou, E Lindstrom, GW Robinson, H Hahn, H Hahn, HA Zahreddine, HJ Sharpe, I Hofmann, J Briscoe, J Chen, J Gao, J Rodon, J Taipale, JM Goldberg, JS Blackburn, JY Tang, KD Robarge, LV Goodrich, M Aszterbaum, M Duman-Scheel, M Sadelain, M Schrappe, MJ Koudijs, NJ Rowbotham, PD Bhola, PD Stenson, PL So, PM LoRusso, RH Ko, RL Johnson, S Hettmer, SB Kaye, SP Hunger, SS Winter, SV Outram, T Ni Chonghaile, TT Vo, Y Liu   +54 more
core   +1 more source

Outcomes, Mortality Causes, and Pathological Findings in European Hedgehogs (Erinaceus europeus, Linnaeus 1758): A Seventeen Year Retrospective Analysis in the North of Portugal

Animals, 2020
This study aimed to analyze the admission causes, outcomes, primary causes of death, and main lesions observed in the post mortem examinations of Western European hedgehogs, Erinaceus europaeus (Linnaeus, 1758), in the north of Portugal.
Andreia Garcês, Vanessa Soeiro, Sara Lóio, Roberto Sargo, Luís Sousa, Filipe Silva, Isabel Pires   +6 more
doaj   +1 more source

NMR Study of the New Magnetic Superconductor CaK(Fe$0.951Ni0.049)4As4: Microscopic Coexistence of Hedgehog Spin-vortex Crystal and Superconductivity [PDF]

, 2017
Coexistence of a new-type antiferromagnetic (AFM) state, the so-called hedgehog spin-vortex crystal (SVC), and superconductivity (SC) is evidenced by $^{75}$As nuclear magnetic resonance study on single-crystalline CaK(Fe$_{0.951}$Ni$_{0.049}$)$_4$As$_4$.
Bud’ko, S., Böhmer, A., Canfield, Paul, Canfield, Paul, Ding, Qing-Ping, Furukawa, Yuji, Meier, William   +6 more
core   +4 more sources