Results 221 to 230 of about 113,623 (349)

POU5F1 bridges Hedgehog signaling and epithelial remodeling in COPD. [PDF]

Front Cell Dev Biol
Petit LMG, Belgacemi R, Mulette P, Brisebarre A, Saber Cherif L, Devilliers MA, Hatoum S, Ancel J, Delepine G, Durlach A, Polette M, Deslée G, Perotin JM, Dormoy V.   +13 more
europepmc   +1 more source

The Spleen Promotes Liver Sinusoidal Endothelial Cell Angiogenesis by Stimulating the TGFβ/Smad2/3 Pathway Through GDF15

Journal of Gastroenterology and Hepatology, EarlyView.
ABSTRACT Background and Aims Liver sinusoidal endothelial cells (LSECs) are crucial nonparenchymal cells involved in liver fibrosis progression. Liver fibrosis develops from various chronic liver diseases, with pathological progression associated with the spleen. However, the precise mechanism by which the spleen influences LSECs during fibrosis is not
Xi Deng, Na Huang, Ke Du, Hailong Zhang, Ziwei Du, Yudan Fan, Mengchen Zhu, Pengfei Liu, Yanhua Mu, Zongfang Li   +9 more
wiley   +1 more source

Protein kinase A antagonizes Hedgehog signaling by regulating both the activator and repressor forms of Cubitus interruptus [PDF]

, 1999
Ge Wang, Boyuan Wang, Jin Jiang
openalex   +1 more source

SLC25A39 regulates Hedgehog signaling to promote tumor progression and sorafenib resistance in hepatocellular carcinoma. [PDF]

Sci Rep
Qiu Q, Yin H, Zhang L, Xu W, Zhu S, Zhang Q, Zhao M, Qian Y, Ruan Y, Zhang H, Wu Z, Liu J, Ke J, Dai Y, Wang W, Sun W, Gao Y, Xu H.   +17 more
europepmc   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

The Prognostic Value of the Hedgehog Signaling Pathway in Ovarian Cancer. [PDF]

Int J Mol Sci
Salman ND, Hanker LC, Győrffy B, Bartha Á, Proppe L, Götte M.   +5 more
europepmc   +1 more source

Mandibular Condylar Cartilage in Development and Diseases: A PTHrP‐Centric View

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT The mandibular condylar cartilage (MCC) is a dual‐function component of the temporomandibular joint (TMJ), acting as both articular cartilage for jaw movement and growth cartilage for vertical growth of the mandibular condyle. Parathyroid hormone‐related protein (PTHrP) plays a critical role in orchestrating chondrogenesis in the long bone ...
Chiaki Tsutsumi‐Arai, Amy Tran, Yuki Arai, Wanida Ono, Noriaki Ono   +4 more
wiley   +1 more source

Notch signalling maintains Hedgehog responsiveness via a Gli-dependent mechanism during spinal cord patterning in zebrafish

, 2019
Craig T. Jacobs, Peng Huang
openalex   +1 more source

Lysosomal glucocerebrosidase is needed for ciliary Hedgehog signaling: A convergent pathway contributing to Parkinson's disease. [PDF]

Proc Natl Acad Sci U S A
Nair SV, Jaimon E, Adhikari A, Nikoloff J, Pfeffer SR.   +4 more
europepmc   +1 more source

Utilising Next‐Generation Sequencing to Explore the Molecular Etiology of Short Root Anomaly

Orthodontics &Craniofacial Research, EarlyView.
ABSTRACT Objective Short Root Anomaly (SRA) is a genetic dental disorder affecting tooth root development. The affected teeth have abnormally short roots and significantly reduced root to crown ratios. The aim of this study was to determine the mode of inheritance and the molecular aetiology of SRA in identified Hispanic families.
Emily A. Joy, David K. Crossman, Mary MacDougall, Quamarul Hassan, Ejvis Lamani   +4 more
wiley   +1 more source