Results 221 to 230 of about 4,715,625 (390)

Hedgehog-Dependent Patterning in theDrosophilaEye Can Occur in the Absence of Dpp Signaling

, 1996
Richard Burke, Konrad Basler
openalex   +1 more source

THE COSMOPOLITICS OF CATS AND WILDLIFE ON CAPE TOWN'S URBAN EDGE

International Journal of Urban and Regional Research, EarlyView.
Abstract Free‐ranging cats are widely tolerated in cities, and animal welfare organizations increasingly allow for ‘trap, neuter and release’ (TNR) of unowned cats. We show, using the example of a university campus adjacent to a national park in a large metropole, that this has implications for cosmopolitics over biodiversity on the urban edge.
Nicoli Nattrass, Zoë Woodgate, Benjamin Wittenberg, M. Justin O'Riain   +3 more
wiley   +1 more source

Cholesterol Modification of Sonic Hedgehog Is Required for Long-Range Signaling Activity and Effective Modulation of Signaling by Ptc1 [PDF]

, 2001
Paula Lewis, Matthew Dunn, Jill A. McMahon, Malcolm Logan, James F. Martin, Benoit St‐Jacques, Andrew P. McMahon   +6 more
openalex   +1 more source

Improving the integration of artificial intelligence into existing ecological inference workflows

Methods in Ecology and Evolution, EarlyView.
Abstract Artificial intelligence (AI) has revolutionised the process of identifying species and individuals in audio recordings and camera trap images. However, despite developments in sensor technology, machine learning and statistical methods, a general AI‐assisted data‐to‐inference pipeline has yet to emerge. We argue that this is, in part, due to a
Amber Cowans, Xavier Lambin, Darragh Hare, Chris Sutherland   +3 more
wiley   +1 more source

Zebrafish mutations in Gli-mediated hedgehog signaling lead to lens transdifferentiation from the adenohypophysis anlage

, 2000
Hisato Kondoh, Masanori Uchikawa, Hiroki Yoda, Hiroyuki Takeda, Makoto Furutani‐Seiki, Rolf O. Karlstrom   +5 more
openalex   +1 more source

Age‐Associated Decline in Autophagy Pathways in the Retinal Pigment Epithelium and Protective Effects of Topical Trehalose in Light‐Induced Outer Retinal Degeneration in Mice

Aging Cell, EarlyView.
Transcriptomic analyses reveal an age‐related decline in autophagy pathways in RPE/choroid. These pathways remain unchanged in early AMD but become bidirectionally dysregulated in later stages, along with increased RPE loss. Pre‐treatment with trehalose eyedrops enhances RPE autophagy flux and prevents light‐induced outer retinal degeneration in mice ...
Katherine Cox, Gongyu Shi, Neve Read, Mohamed T. Patel, Kepeng Ou, Zijia Liu, Jiahui Wu, Suci Cendanawati, Jenna Le Brun Powell, Pola Goldberg Oppenheimer, Lisa J. Hill, Lindsay B. Nicholson, Andrew D. Dick, Jian Liu   +13 more
wiley   +1 more source

Cross‐Analysis of Single‐Cell Transcriptomic Datasets Reveals Conserved Neurogenic Gene Signatures and New Insights Into Neural Stem Cell Aging

Aging Cell, EarlyView.
Here, we reanalyze single‐cell RNA sequencing datasets demonstrating hippocampal adult neural stem cell (NSC) heterogeneity to resolve classification inconsistencies and identify conserved gene markers. Our findings enhance understanding of NSC dynamics, aging, and senescence, providing a framework for standardized classification and improved insights ...
Oliver Polzer, E. Kinloch, P. J. Lucassen, E. Salta, C. P. Fitzsimons   +4 more
wiley   +1 more source

Hedgehog signaling in osteoarthritis [PDF]

Osteoarthritis and Cartilage, 2013
openaire   +2 more sources

Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients

Aging Cell, EarlyView.
In male patients undergoing CABG surgery, pretreatment with quercetin suppressed inflammaging and its associated inflammation, leading to improved endothelium‐dependent relaxation (measured ex vivo) and reducing new onset of post‐operative atrial fibrillation.
Pauline Mury, Olina Dagher, Annik Fortier, Ariel Diaz, Yoan Lamarche, Pierre‐Emmanuel Noly, Marina Ibrahim, Pierre Pagé, Philippe Demers, Denis Bouchard, Pierre‐Luc Bernier, Nancy Poirier, Emmanuel Moss, Nicolas Durrleman, Hughes Jeanmart, Michel Pellerin, Guillaume Lettre, Nathalie Thorin‐Trescases, Michel Carrier, Eric Thorin   +19 more
wiley   +1 more source

A luminal non‐coding RNA‐based genomic classifier confirms favourable outcomes in patients with clinically organ‐confined bladder cancer treated with radical cystectomy

BJU International, Volume 135, Issue 4, Page 648-656, April 2025.
Objective To further evaluate a genomic classifier (GC) in a cohort of patients undergoing radical cystectomy (RC), as long non‐coding RNA (lncRNA)‐based genomic profiling has suggested utility in identifying a distinct tumour subgroup corresponding to a favourable prognosis in patients with bladder cancer.
Joep J. de Jong, James A. Proudfoot, Siamak Daneshmand, Robert S. Svatek, Vikram Narayan, Ewan A. Gibb, Elai Davicioni, Shreyas Joshi, Aaron Dahmen, Roger Li, Brant A. Inman, Paras Shah, Iftach Chaplin, Jonathan Wright, Yair Lotan   +14 more
wiley   +1 more source