Results 231 to 240 of about 113,623 (349)

Identification of Hedgehog signaling inhibitors with relevant human exposure by small molecule screening

, 2010
Robert J. Lipinski, Wade Bushman
openalex   +2 more sources

New Insights into the Molecular Actions of Grosheimin, Costunolide, and α- and β-Cyclocostunolide on Primary Cilia Structure and Hedgehog Signaling. [PDF]

Int J Mol Sci
Murillo-Pineda M, Martínez-Miralles J, Medina-Calzada Z, Varela RM, Macías FA, Chinchilla N, Juárez-Soto Á, Santpere G, Reales E.   +8 more
europepmc   +1 more source

Bacterial Involvement in Oral Squamous Cell Carcinoma and Potentially Malignant Oral Disorders

Oral Diseases, EarlyView.
ABSTRACT Objective To clarify the relationship between oral squamous cell carcinoma (OSCC), potentially malignant oral disease (OPMD), and bacterial flora using metagenomic analysis. Methods This cross‐sectional observational study included 50 patients in the control group and 77 patients with OPMDs, 41 with early OSCCs, and 20 with advanced OSCCs ...
Atsumu Koketsu, Satoshi Fukase, Toru Tamahara, Tatsuru Saito, Akiko Ito, Yutaro Higashi, Tomonari Kajita, Tsuyoshi Kurobane, Masaaki Miyakoshi, Masahiro Iikubo, Kazuki Kumada, Bin Li, Muneaki Shimada, Ritsuko Shimizu, Tetsu Takahashi, Kensuke Yamauchi, Tsuyoshi Sugiura   +16 more
wiley   +1 more source

Inflammation and mechanical force‐induced bone remodeling

Periodontology 2000, EarlyView.
Abstract Periodontitis arises from imbalanced host–microbe interactions, leading to dysbiosis and destructive inflammation. The host's innate and adaptive immune responses produce pro‐inflammatory mediators that stimulate destructive events, which cause loss of alveolar bone and connective tissue attachment.
Hyeran Helen Jeon, Xin Huang, Leticia Rojas Cortez, Puttipong Sripinun, Jung‐me Lee, Julie J. Hong, Dana T. Graves   +6 more
wiley   +1 more source

Simultaneous inhibition of hedgehog signaling and tumor proliferation remodels stroma and enhances pancreatic cancer therapy

, 2018
Jun Zhao, Huamin Wang, Cheng-Hui Hsiao, Diana S‐L Chow, Eugene J. Koay, Ya’an Kang, Xiaoxia Wen, Qian Huang, Ying Ma, James A. Bankson, Stephen E. Ullrich, Willem W. Overwijk, Anirban Maitra, David Piwnica‐Worms, Jason B. Fleming, Chun Li   +15 more
openalex   +2 more sources

The Role of Hedgehog Signaling in Non-small Cell Lung Cancer: Targeting Tumor Invasion, Therapy Resistance and Novel Therapeutic Strategies. [PDF]

Int J Biol Sci
Kang Y, Zheng H, Wen Q, Fan S.
europepmc   +1 more source

“Is This Edible Anyway?” The Impact of Culture on the Evolution (and Devolution) of Mushroom Knowledge

Topics in Cognitive Science, EarlyView.
Abstract Mushrooms are a ubiquitous and essential component in our biological environment and have been of interest to humans around the globe for millennia. Knowledge about mushrooms represents a prime example of cumulative culture, one of the key processes in human evolution.
Andrea Bender, Åge Oterhals
wiley   +1 more source

Hedgehog Signaling in Hepatocellular Carcinoma

, 2019
Isaac S. Chan
openalex   +2 more sources

Signaling in Simple Steatosis and Non-alcoholic Steatohepatitis Cirrhosis: TGF-β1, YAP/TAZ, and Hedgehog Pathway Activity [PDF]

, 2018
Sina Mohagheghi, Zohreh Khajehahmadi, Heidar Tavilani   +2 more
openalex   +1 more source

MYB Activates the Hedgehog Signaling Pathway to Repress Natural Killer Cytotoxicity in Cervical Cancer. [PDF]

Kaohsiung J Med Sci
Wang Y, Li C.
europepmc   +1 more source