Results 241 to 250 of about 113,623 (349)

Cerebrovascular pulsatility following long duration spaceflight is associated with changes in pulse pressure and carotid artery stiffness

Experimental Physiology, EarlyView.
Abstract Central artery stiffening increases the haemodynamic pulsations transmitted downstream towards target organs, including the brain. While recent evidence suggests that long duration spaceflight is associated with reduced common carotid artery (CCA) distensibility, cerebrovascular pulsatility has not been extensively characterized in astronauts.
Roxanne Fournier, Danielle K. Greaves, J. Kevin Shoemaker, Philippe Arbeille, Richard L. Hughson, Andrew D. Robertson   +5 more
wiley   +1 more source

A recurrent mosaic mutation in SMO, encoding the hedgehog signal transducer smoothened, is the major cause of Curry-Jones syndrome [PDF]

, 2016
et al,, Grange, Dorothy K
core   +1 more source

Sonic Hedgehog Signaling is Negatively Regulated in Reactive Astrocytes Following Forebrain Stab Injury

, 2019
R. Vivian Allahyari, Rava Vivian Allahyari, Anna Denise R. Garcia   +2 more
openalex   +1 more source

EVC protein regulates Sonic hedgehog signaling during human intervertebral disc development and degeneration. [PDF]

iScience
Wu Z, Shaw L, Dube CT, Ionescu AM, Qiu T, Tierney AL, Baird P, Patel S, Zeef LAH, Birchall LJ, Jennings RE, Hanley NA, Unwin RD, Hoyland JA, Richardson SM.   +14 more
europepmc   +1 more source

Spaceborne and spaceborn: Physiological aspects of pregnancy and birth during interplanetary flight

Experimental Physiology, EarlyView.
Abstract Crewed interplanetary return missions that are on the planning horizon will take years, more than enough time for initiation and completion of a pregnancy. Pregnancy is viewed as a sequence of processes – fertilization, blastocyst formation, implantation, gastrulation, placentation, organogenesis, gross morphogenesis, birth and neonatal ...
Arun V. Holden
wiley   +1 more source

Dual-Lineage Chondrocyte-Like Cells in the Nucleus Pulposus of Aging Intervertebral Discs Are Accelerated by Hedgehog Signaling Inactivation. [PDF]

Aging Cell
Zhang L, Xiu C, You H, Chen J.
europepmc   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

The Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya, Rimma Dugarova, Shefeeq M. Theparambil   +2 more
wiley   +1 more source

Stromal Hedgehog Signaling Is Associated with Favorable Outcomes in Pancreatic Cancer. [PDF]

Int J Mol Sci
Manoukian P, Damhofer H, Zhao L, van Laarhoven HWM, Bijlsma MF.   +4 more
europepmc   +1 more source

Mitochondrial control of ciliary gene expression and structure in striatal neurons

The Journal of Physiology, EarlyView.
Abstract figure legend Neurons drive animal behaviour by receiving and transmitting information and require energy, primarily supplied by mitochondria, to function. Additionally, neurons need to sense environmental changes to adapt, a function that is locally played by the primary cilia.
Dogukan H. Ulgen, Alessandro Chioino, Olivia Zanoletti, Albert Quintana, Elisenda Sanz, Carmen Sandi   +5 more
wiley   +1 more source

CK2α, over-expressed in human malignant pleural mesothelioma, regulates the Hedgehog signaling pathway in mesothelioma cells [PDF]

, 2014
Shulin Zhang, Yi‐Lin Yang, Yucheng Wang, Bin You, Yuyuan Dai, Geraldine Chan, David Hsieh, Il-Jin Kim, Li Tai Fang, Alfred Au, Hubert Stöppler, Zhidong Xu, David M. Jablons, Liang You   +13 more
openalex   +1 more source