Results 241 to 250 of about 416,052 (359)

Non-canonical functions of DNMT3A in hematopoietic stem cells regulate telomerase activity and genome integrity. [PDF]

Cell Stem Cell
Xavier Raj I, Kyun Koh W, Harrison J, Zhang CR, Soares B, Amato R, Krishnan A, O'Leary DR, Bjeije H, Parsons TM, Han W, Young AL, Wang T, Batista LFZ, Challen GA.   +14 more
europepmc   +1 more source

Asymmetric Cu─N─Ru Bridgedsite Nanozyme‐Loaded Injectable Thermogel Boosts Cuproptosis‐Like Death for Multidrug‐Resistant Urinary Tract Infections

Advanced Science, EarlyView.
To address multidrug‐resistant urinary tract infections (MDR‐UTIs), we developed Cu‐ZIF8‐Ru nanozyme featuring an asymmetric Cu─N─Ru catalytic site. This unique structure enhances multienzyme‐mimetic activity, eradicating resistant bacteria by inducing a cuproptosis‐like death pathway through intracellular Cu2+ accumulation and energy depletion.
Guanlin Li, Shike Zhang, Jinggong Liu, Xin Wang, Heng Wang, Hongcan Yang, Yuhao Zhou, Wen Liu, Hongxing Liu, Wenqi Wu   +9 more
wiley   +1 more source

Differentiation latency and dormancy signatures define fetal liver hematopoietic stem cells at single-cell resolution. [PDF]

Cell Rep
Ishida T, Mercoli J, Heck AM, Phelps I, Varnum-Finney B, Dozono S, Nourigat-McKay C, Kraskouskas K, Wellington R, Waltner O, Jackson DL, Delaney C, Rafii S, Bernstein ID, Aldinger KA, Birth Defects Research Laboratory (BDRL),, Trapnell C, Zhao HG, Hadland B.   +18 more
europepmc   +1 more source

Cytarabine Monotherapy as Bridging Treatment for Hematopoietic Stem Cell Transplantation in Children with Juvenile Myelomonocytic Leukemia

, 2012
Woo Suck Suh, Mun Sung Cho, Jae Wook Lee, Pil Sang Jang, Nack Gyun Chung, Dae Chul Jeong, Bin Cho, Hack Ki Kim   +7 more
openalex   +1 more source

[The role of mesenchymal stem cells in allogeneic hematopoietic stem cell transplantation for patients with refractory severe aplastic anemia].

, 2019
Min Zhao, Yuewen Fu, Qiang Wang, Hui‐Sheng Ai, Y Q Wang, Jun Zhou, Baijun Fang, Xing Wei, Yongping Song   +8 more
openalex   +2 more sources

Engineering Immune Cell to Counteract Aging and Aging‐Associated Diseases

Advanced Science, EarlyView.
This review highlights a paradigm shift in which advanced immune cell therapies, initially developed for cancer, are now being harnessed to combat aging. By engineering immune cells to selectively clear senescent cells and remodel pro‐inflammatory tissue microenvironments, these strategies offer a novel and powerful approach to delay age‐related ...
Jianhua Guo, Lanjie Lei, Ying Jin, Lan Su, Shumao Cui, Liyun Shi   +5 more
wiley   +1 more source

Author Correction: Clonal evolution of hematopoietic stem cells after autologous stem cell transplantation. [PDF]

Nat Genet
Uryu H, Saeki K, Haeno H, Kapadia CD, Furudate K, Nangalia J, Spencer Chapman M, Zhang L, Padilla J, Zhao L, Hsu JI, Zhao C, Chen S, Tanaka T, Li Z, Ogata S, Hanache S, Yang H, DiNardo C, Daver N, Pemmaraju N, Jain N, Ravandi F, Zhang J, Song X, Thompson E, Tang H, Little L, Gumbs C, Orlowski RZ, Qazilbash M, Bhalla K, Colla S, Kantarjian H, Kanagal-Shamanna R, Bueso-Ramos C, Nakada D, Al-Atrash G, Molldrem J, Futreal PA, Shpall E, Goodell M, Garcia-Manero G, Takahashi K.   +43 more
europepmc   +1 more source

Biological markers of bronchiolitis obliterans syndrome in recipients of allogeneic hematopoietic stem cell transplantation

Е. А. Кулагин, В. И. Трофимов   +1 more
openalex   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Distinct roles for NF-κB in hematopoietic stem cells and the bone marrow milieu in promoting hematopoietic aging. [PDF]

Cell Rep
Chia JJ, Singh A, Lin YS, Popko N, Mastro D, Liu Y, Tran T, King JK, Rao DS, Hoffmann A.   +9 more
europepmc   +1 more source