Results 241 to 250 of about 1,162,311 (403)
Similar Outcome With Haploidentical, Matched Sibling, or Matched Unrelated Donor Hematopoietic Cell Transplantation for Adult Patients With Adverse‐Risk TP53‐Mutated Acute Myeloid Leukemia in First Remission: A Comparative Study From the Global Committee and the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation
American Journal of Hematology, EarlyView.ABSTRACT
Given the dismal prognosis for patients with TP53‐mutated acute myeloid leukemia (AML), the optimal donor for those undergoing allogeneic hematopoietic cell transplantation (allo‐HCT) remains unclear. We retrospectively analyzed adult patients with TP53‐mutated AML who underwent first allo‐HCT in CR1 between 2010 and 2021.Yuhua Ru, Jia Chen, Allain‐Thibeault Ferhat, Hélène Labussière‐Wallet, Tobias Gedde‐Dahl, Nicolaus Kröger, Gérard Socié, Ibrahim Yakoub‐Agha, Matthias Eder, Stephan Mielke, Depei Wu, Mohamad Mohty, Fabio Ciceri, Norbert‐Claude Gorin +13 morewiley +1 more sourceReal World Study on the Best CPX‐351 Treatment Duration and Timing for Allogeneic Stem Cell Transplantation
American Journal of Hematology, EarlyView.ABSTRACT
In the registration clinical trial 301 (NCT01696084), CPX‐351 has shown to be superior to conventional 3 + 7 in secondary AML (s‐AML). However, the optimal duration of treatment, the best timing for allogeneic stem cell transplantation (allo‐HSCT), and the activity of CPX‐351 in specific s‐AML subgroups are unclear.Fabio Guolo, Luana Fianchi, Maria Paola Martelli, Federico Lussana, Francesco Grimaldi, Federica Pilo, Michela Rondoni, Carla Filì, Paola Minetto, Debora Capelli, Patrizia Chiusolo, Massimo Breccia, Sara Mastaglio, Massimo Bernardi, Monica Bocchia, Monica Fumagalli, Sara Galimberti, Valentina Mancini, Anna Lisa Piccioni, Luca Maurillo, Nicola Stefano Fracchiolla, Raffaele Palmieri, Calogero Vetro, Cristina Papayannidis, Lorenzo Brunetti, Alessandra Sperotto, Federica Gigli, Patrizia Zappasodi, Antonino Mulé, Caterina Patti, Erika Borlenghi, Michelina Dargenio, Federica Lessi, Marco Cerrano, Daniela Cilloni, Alessandro Isidori, Monia Lunghi, Caterina Alati, Carmela Gurrieri, Carola Riva, Giovanni Marconi, Ivana Lotesoriere, Samuele Gatani, Anna Maria Scattolin, Manuela Caizzi, Salvatore Perrone, Atto Billio, Filippo Gherlinzoni, Francesco Mannelli, Michele Gottardi, Roberto Cairoli, Anna Candoni, Felicetto Ferrara, Livio Pagano, Roberto Massimo Lemoli, Adriano Venditti, Elisabetta Todisco +56 morewiley +1 more sourceClonal evolution of hematopoietic stem cells after autologous stem cell transplantation. [PDF]
Nat GenetUryu H, Saeki K, Haeno H, Kapadia CD, Furudate K, Nangalia J, Spencer Chapman M, Zhang L, Padilla J, Zhao L, Hsu JI, Zhao C, Chen S, Tanaka T, Li Z, Ogata S, Hanache S, Yang H, DiNardo C, Daver N, Pemmaraju N, Jain N, Ravandi F, Zhang J, Song X, Thompson E, Tang H, Little L, Gumbs C, Orlowski RZ, Qazilbash M, Bhalla K, Colla S, Kantarjian H, Kanagal-Shamanna R, Bueso-Ramos C, Nakada D, Al-Atrash G, Molldrem J, Futreal PA, Shpall E, Goodell M, Garcia-Manero G, Takahashi K. +43 moreeuropepmc +1 more sourceRisk Factors for and Impact of Pre‐Engraftment Syndrome on Outcomes Following Single‐Unit Cord Blood Transplantation in Adults
American Journal of Hematology, EarlyView.ABSTRACT
Pre‐engraftment syndrome (PES) is a unique complication of cord blood transplantation (CBT) whose risk factors and impact on transplant outcomes remain controversial. Using a nationwide database in Japan, we analyzed a total of 3734 patients who underwent single‐unit CBT.Masatoshi Sakurai, Keisuke Kataoka, Kota Mizuno, Takuto Mori, Shuichi Shirane, Hirotoshi Sakaguchi, Takehiko Mori, Masatsugu Tanaka, Masahito Tokunaga, Makoto Onizuka, Mamiko Sakata‐Yanagimoto, Jun Ishikawa, Yuta Katayama, Shuichi Ota, Masashi Sawa, Jun Kato, Yuta Hasegawa, Koichi Onodera, Norimichi Hattori, Shigesaburo Miyakoshi, Nobuyuki Takayama, Tetsuya Nishida, Koji Kato, Fumihiko Ishimaru, Yoshiko Atsuta, Junya Kanda, Hideki Nakasone, Seitaro Terakura +27 morewiley +1 more sourceIschemic Stroke Activates Hematopoietic Bone Marrow Stem Cells
Circulation Research, 2015 G. Courties, F. Herisson, H. Sager, T. Heidt, Yuxiang Ye, Ying Wei, Yuan Sun, N. Severe, Partha Dutta, Jennifer Scharff, D. Scadden, R. Weissleder, F. Swirski, M. Moskowitz, M. Nahrendorf +14 moresemanticscholar +1 more sourceAllogeneic Hematopoietic Stem Cell Transplantation in Adolescents and Young Adults With Acute Lymphoblastic Leukemia—A Retrospective, Dual‐Center Study
American Journal of Hematology, EarlyView.ABSTRACT
Survival outcomes for adolescents and young adults (AYAs) with acute lymphoblastic leukemia (ALL) have improved with modern frontline therapies and minimal residual disease (MRD)‐guided strategies. As a result, allogeneic hematopoietic cell transplantation (HCT) is increasingly deferred in first remission (CR1) and used in the relapsed setting.Oren Pasvolsky, Shai Shimony, Rima M. Saliba, Curtis Marcoux, Celina Ledesma, Gabriela Rondon, Priti Tewari, Dristhi Ragoonanan, Nicholas J. Short, Elias Jabbour, Mahasweta Gooptu, Vincent T. Ho, Robert J. Soiffer, Joseph H. Antin, John Koreth, Corey S. Cutler, Jonathan D. Paolino, Christine N. Duncan, Leslie E. Lehmann, Daniel J. DeAngelo, Nitin Jain, Richard Champlin, Elizabeth Shpall, Marlise R. Luskin, Partow Kebriaei +24 morewiley +1 more source