Results 81 to 90 of about 213,829 (198)

Heme oxygenase isoforms differ in their subcellular trafficking during hypoxia and are differentially modulated by cytochrome P450 reductase. [PDF]

open access: yesPLoS ONE, 2012
Heme oxygenase (HO) degrades heme in concert with NADPH cytochrome P450 reductase (CPR) which donates electrons to the reaction. Earlier studies reveal the importance of the hydrophobic carboxy-terminus of HO-1 for anchorage to the endoplasmic reticulum (
Monika Linnenbaum   +3 more
doaj   +1 more source

Linagliptin increases the expression of LRP2 independent of Nrf2 in streptozotocin‐induced diabetic mice

open access: yesJournal of Diabetes Investigation, EarlyView.
ABSTRACT Aims/Introduction Oxidative stress is thought to play a role in the onset and progression of diabetic nephropathy (DN). Nuclear factor erythroid‐related factor 2 (Nrf2) is a master regulator of antioxidant and detoxification pathways and provides cellular protection against oxidative stress.
Suratsawadee Promsuwan   +5 more
wiley   +1 more source

Molecular insights into frataxin-mediated iron supply for heme biosynthesis in Bacillus subtilis.

open access: yesPLoS ONE, 2015
Iron is required as an element to sustain life in all eukaryotes and most bacteria. Although several bacterial iron acquisition strategies have been well explored, little is known about the intracellular trafficking pathways of iron and its entry into ...
Andreas Mielcarek   +3 more
doaj   +1 more source

Inflammatory and Immunological Basis of Periodontal Diseases

open access: yesJournal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima   +3 more
wiley   +1 more source

South Carolina Human Trafficking Task Force newsletter

open access: yes, 2020
This quarterly newsletter is released by the South Carolina Human Trafficking Task Force. As South Carolina's anti-human trafficking movement continues to grow, the State Task Force designed this newsletter to promote information sharing and ...
South Carolina Human Trafficking Task Force
core   +3 more sources

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini   +3 more
wiley   +1 more source

Human trafficking involving marriage and partner migration to Australia [PDF]

open access: yes, 2014
: In this report, what is known about human trafficking involving marriage and partner migration to Australia is described, drawing on primary information obtained from victim/survivor testimonies, stakeholder knowledge and expertise, and reported cases ...
Samantha Lyneham   +3 more
core   +1 more source

Human trafficking & temporary guestworker visas

open access: yes, 2023
This flier contains information about human trafficking and temporary guestworker ...
South Carolina Human Trafficking Task Force
core  

A specialized pathway for erythroid iron delivery through lysosomal trafficking of transferrin receptor 2

open access: yesBlood Advances, 2017
: Erythroid progenitors are the largest consumers of iron in the human body. In these cells, a high flux of iron must reach the mitochondrial matrix to form sufficient heme to support hemoglobinization. Canonical erythroid iron trafficking occurs via the
Shadi Khalil   +6 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy