Results 71 to 80 of about 3,016 (188)

Hemifusion of giant unilamellar vesicles with planar hydrophobic surfaces: a fluorescence microscopy study.

open access: yes, 2018
Vesicle adhesion and fusion to interfaces are frequently used for the construction of biomimetic surfaces in biosensors and drug delivery. Ubiquitous in cell biology, vesicle fusion involves the transformation of two separate membranes into one ...
Mathias Losche (5067464)   +4 more
core   +1 more source

Septins in the Middle—Makers and Breakers of Membrane Contact Sites

open access: yesJournal of Neurochemistry, Volume 170, Issue 6, June 2026.
Septins are a family of GTP‐binding proteins that assemble into heteromeric oligomers and polymers, associating with specific membrane domains and organelles according to their subunit composition. Growing evidence places septins at membrane contact sites (MCS) — key hubs for intracellular communication that mediate exchange of ions, lipids, and ...
TrishaJean J. Holt, Elias T. Spiliotis
wiley   +1 more source

Role of Abl kinase and the Wave2 signaling complex in HIV-1 entry at a post-hemifusion step. [PDF]

open access: yesPLoS Pathogens, 2010
Entry of human immunodeficiency virus type 1 (HIV-1) commences with binding of the envelope glycoprotein (Env) to the receptor CD4, and one of two coreceptors, CXCR4 or CCR5.
Brooke Harmon   +2 more
doaj   +1 more source

The reduction in voltage dependence caused by incorporating NBD-PG into membranes occurs downstream of hemifusion.

open access: yes, 2013
Upper panel: Effector cells (open ellipse) expressing VSV G were bound, at 4°C, to target cells (filled ellipse) that were labeled with the lipid probe NBD-PG.
Fredric S. Cohen (277044)   +1 more
core   +1 more source

Monkeypox Virus: Epidemiology, Virology, Diagnosis, Vaccine, and Therapeutics

open access: yesMedComm, Volume 7, Issue 1, January 2026.
This review provides a comprehensive overview of the latest research advances in MPXV, with a focused analysis across five core dimensions: epidemiology, virology, diagnosis, vaccine, and therapeutics. The primary objective of this review is to advance the understanding of MPXV and facilitate the development of more effective diagnostic methods ...
Yunzheng Yan   +14 more
wiley   +1 more source

Search for a link between protein fusion pore and hemifusion intermediates in SNARE driven membrane fusion [PDF]

open access: yes, 2005
SNARE driven membrane fusion proceeds through an unknown process of events. It is still a mystery whether there is one chronological order of events for SNARE fusion or if there are multiple pathways. Two intermediates, hemifusion and protein fusion pore,
Hecker, Robert
core  

Real-time intermembrane force measurements and imaging of lipid domain morphology during hemifusion [PDF]

open access: yes, 2015
Membrane fusion is the core process in membrane trafficking and is essential for cellular transport of proteins and other biomacromolecules. During protein-mediated membrane fusion, membrane proteins are often excluded from the membrane-membrane contact,
Donaldson, Jr., Stephen H   +7 more
core   +1 more source

Extracellular Vesicle‐Based mRNA Therapeutics and Vaccines

open access: yesExploration, Volume 5, Issue 6, December 2025.
This review provides a comprehensive analysis of recent advancements in extracellular vesicle (EV)‐based messenger RNA (mRNA) applications for therapeutics and vaccines. It systematically outlines strategies for mRNA encapsulation within EVs and elucidates the challenges associated with this technology, offering insights into future research directions
Qi Li   +6 more
wiley   +1 more source

Control of membrane fusion mechanism by lipid composition: predictions from ensemble molecular dynamics. [PDF]

open access: yesPLoS Computational Biology, 2007
Membrane fusion is critical to biological processes such as viral infection, endocrine hormone secretion, and neurotransmission, yet the precise mechanistic details of the fusion process remain unknown.
Peter M Kasson, Vijay S Pande
doaj   +1 more source

HIV‐1 viral protein effect on cerebral microvasculature: An in vitro blood–brain barrier model

open access: yesPhysiological Reports, Volume 13, Issue 19, October 2025.
Abstract The central nervous system (CNS) serves as a sanctuary for the Human Immunodeficiency Virus (HIV), which is facilitated by HIV's ability to breach the blood–brain barrier (BBB). BBB dysfunction occurs in the earliest stages of an HIV‐1 infection.
Sinelisiwe Matubatuba   +5 more
wiley   +1 more source

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