Results 81 to 90 of about 3,016 (188)
Advanced Healthcare Materials, Volume 14, Issue 23, September 8, 2025.Extracellular vesicles (EVs) are pivotal mediators of intercellular communication and disease, yet the fundamental mechanisms controlling their biogenesis and cargo selection remain unclear. This limitation hinders their diagnostic utility and therapeutic development.
Luís Carvalho Ferraz +2 more
wiley +1 more source
A distinct tethering step is vital for vacuole membrane fusion
eLife, 2014 Past experiments with reconstituted proteoliposomes, employing assays that infer membrane fusion from fluorescent lipid dequenching, have suggested that vacuolar SNAREs alone suffice to catalyze membrane fusion in vitro.
Michael Zick, William T Wickner
doaj +1 more source
Cooperative Function of Atg8‐ and TORC1‐Mediated Activities in Yeast
Yeast, Volume 42, Issue 8-10, Page 161-168, September 2025.The atg8Δ mutant is sensitive to rapamycin, and both lipidation‐dependent and ‐independent functions of Atg8 are necessary for survival during impaired TORC1 activity. Atg8‐ and TORC1‐mediated functions may contribute to maintaining vacuolar functions.
Yumiko Oba +6 more
wiley +1 more source
, 2009 Exocytosis proceeds through prefusion stages such as hemifusion, but hemifusion is still an elusive intermediate of unknown duration. Using darkfield and fluorescence microscopy in ATII (alveolar type II) cells containing large secretory vesicles (LBs ...
Miklavc, P +5 more
core +1 more source
Angewandte Chemie, Volume 137, Issue 31, July 28, 2025.Die virale Bindung und Fusion stellen frühe Schritte in der Virusinfektion dar. Die oberflächenverstärkte Infrarotabsorptionsspektroskopie ermöglicht die markierungsfreie Beobachtung molekularer Prozesse während der Interaktion des Influenza‐A‐Virus mit einem Wirtszellmembranmodell und liefert chemische Auflösung zur Unterscheidung viraler Proteine ...
Amelie Teresa Heinen +4 more
wiley +1 more source
Adhesion and Merging of Lipid Bilayers: A Method for Measuring the Free Energy of Adhesion and Hemifusion [PDF]
, 2011 Lipid bilayers can be induced to adhere to each other by molecular mediators, and, depending on the lipid composition, such adhesion can lead to merging of the contacting monolayers in a process known as hemifusion.
Lee, Chang-Chun +5 more
core +1 more source
PLoS Pathogens, 2019 Late endosome-resident interferon-induced transmembrane protein 3 (IFITM3) inhibits fusion of diverse viruses, including Influenza A virus (IAV), by a poorly understood mechanism.
Krishna C Suddala +8 more
doaj +1 more source
Imaging single retrovirus entry through alternative receptor isoforms and intermediates of virus-endosome fusion. [PDF]
PLoS Pathogens, 2011 A large group of viruses rely on low pH to activate their fusion proteins that merge the viral envelope with an endosomal membrane, releasing the viral nucleocapsid.
Naveen K Jha +8 more
doaj +1 more source
Angewandte Chemie International Edition, Volume 64, Issue 31, July 28, 2025.Viral binding and fusion are early steps during viral infection. Surface‐enhanced infrared absorption spectroscopy enables the label‐free tracking of molecular events, as the influenza A virus interacts with a host cell model membrane, providing chemical resolution for viral proteins, viral lipids, and host lipids.
Amelie Teresa Heinen +4 more
wiley +1 more source
Dengue virus ensures its fusion in late endosomes using compartment-specific lipids. [PDF]
PLoS Pathogens, 2010 Many enveloped viruses invade cells via endocytosis and use different environmental factors as triggers for virus-endosome fusion that delivers viral genome into cytosol.
Elena Zaitseva +4 more
doaj +1 more source