RNase A does not translocate the alpha-hemolysin pore. [PDF]
PLoS ONE, 2014 The application of nanopore sensing utilizing the α-hemolysin pore to probe proteins at single-molecule resolution has expanded rapidly. In some studies protein translocation through the α-hemolysin has been reported. However, there is no direct evidence,
Besnik Krasniqi, Jeremy S Lee
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Staphylococcus aureus alpha-hemolysin activates the NLRP3-inflammasome in human and mouse monocytic cells. [PDF]
PLoS ONE, 2009 Community Acquired Methicillin Resistant Staphylococcus aureus (CA-MRSA) causes severe necrotizing infections of the skin, soft tissues, and lungs. Staphylococcal alpha-hemolysin is an essential virulence factor in mouse models of CA-MRSA necrotizing ...
Robin R Craven +7 more
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Targeted Regulation of Protein Expression in Vibrio parahaemolyticus [PDF]
BiologyV. parahaemolyticus has several virulence factors, including thermostable direct hemolysin (TDH), TDH-related hemolysin (TRH), and two separate type III secretion systems (T3SSs), T3SS1 and T3SS2.
Takashi Uebanso +7 more
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Hemolysin Co-regulated Family Proteins Hcp1 and Hcp2 Contribute to Edwardsiella ictaluri Pathogenesis [PDF]
Frontiers in Veterinary Science, 2021 Edwardsiella ictaluri is a Gram-negative facultative intracellular pathogen causing enteric septicemia of catfish (ESC), a devastating disease resulting in significant economic losses in the U.S. catfish industry. Bacterial secretion systems are involved
Safak Kalindamar +4 more
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Structural Insights into Clostridium perfringens Delta Toxin Pore Formation. [PDF]
PLoS ONE, 2013 Clostridium perfringens Delta toxin is one of the three hemolysin-like proteins produced by C. perfringens type C and possibly type B strains. One of the others, NetB, has been shown to be the major cause of Avian Nectrotic Enteritis, which following the
Jessica Huyet +5 more
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Extracellular overexpression of recombinant
Microbial Cell Factories, 2012 Background Extracellular expression of proteins has an absolute advantage in a large-scale industrial production. In our previous study, Thermobifida fusca cutinase, an enzyme mainly utilized in textile industry, was expressed via type II secretory ...
Su Lingqia +5 more
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Conversion of Bacterial Gene Products to Secretion-Competent Fusion Proteins
BioTechniques, 1996 We describe an efficient and easy procedure that allows the generation, detection and secretion of foreign proteins by the secretion apparatus of E. coli hemolysin.
H.-J. Mollenkopf +2 more
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Pore-Forming Toxin-Like Proteins in the Anti-Parasitoid Immune Response of Drosophila
Journal of Innate ImmunityIntroduction: Species of the ananassae subgroup of Drosophilidae are highly resistant to parasitoid wasp infections. We have previously shown that the genes encoding cytolethal distending toxin B (CdtB) and the apoptosis inducing protein of 56
Lilla B. Magyar +8 more
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Insights into the dynamic cell associated and secreted proteome of Staphylococcus aureus cultured in TSB and milk media: a proteomic analysis [PDF]
BMC MicrobiologyThe availability of nutrients is closely linked to the protein expression profile of microorganisms. In this study, a comparative investigation has been performed to examine the expression patterns of cell associated proteins and secreted proteins in ...
Wanting Zhu +9 more
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Escherichia coli Strain – Super-Producer of Vibrio cholerae Hemolysin
Проблемы особо опасных инфекций, 2018 Objective of this work was the cloning of Vibrio cholerae hlyA gene in a plasmid vector providing expression of foreign genes under the control of T5 promoter, and construction of E.
E. V. Monakhova +3 more
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