Results 41 to 50 of about 7,813 (203)
, 2006 Gelatinase B/matrix metalloproteinase-9 (MMP-9), a key regulator and effector of immunity, contains a C-terminal hemopexin domain preceded by a unique linker sequence of ∼64 amino acid residues. This linker sequence is demonstrated to be an extensively O-
Hvidberg, V. +13 more
core +2 more sources
Pharmaceuticals, 2019 This review provides a synopsis of the published literature over the past two years on the heme-binding protein hemopexin (HPX), with some background information on the biochemistry of the HPX system.
Luis Montecinos +2 more
doaj +1 more source
Free heme exacerbates colonic injury induced by anti-cancer therapy
Frontiers in Immunology, 2023 Gastrointestinal inflammation and bleeding are commonly induced by cancer radiotherapy and chemotherapy but mechanisms are unclear. We demonstrated an increased number of infiltrating heme oxygenase-1 positive (HO-1+) macrophages (Mø, CD68+) and the ...
Philippa Seika +12 more
doaj +1 more source
Interactions of Porphyrins with Rabbit Hemopexin
Journal of Biological Chemistry, 1972 Abstract The formation of complexes of rabbit hemopexin with a representative group of porphyrins was investigated to determine the stoichiometry and estimated dissociation constants (Kd) as well as the effect of pH on these interactions. In a 1:1 molar ratio, rabbit apohemopexin (RHx) binds iron-protoporphyrin IX (heme), iron-deuteroporphyrin IX ...
W T, Morgan, U, Muller-Eberhard
openaire +2 more sources
Molecules, 2022 Analysis of protein glycosylation is challenging due to micro- and macro-heterogeneity of the attached glycans. Hydrophilic interaction liquid chromatography (HILIC) is a mode of choice for separation of intact glycopeptides, which are inadequately ...
Petr Kozlik +4 more
doaj +1 more source
Assessment of Ceruloplasmin, Hemopexin, and Haptoglobin in Asthmatic Children [PDF]
, 2020 BACKGROUND: Ceruloplasmin (Cp), haptoglobin, and hemopexin play a role in iron homeostasis and may function to modulate the systemic inflammatory response and be involved in tissue repair.
A. Shahin, Walaa +5 more
core +1 more source
Frontiers in Immunology, 2022 Soil-transmitted helminth [mainly Strongyloidiasis stercoralis (Ss)] and tuberculous lymphadenitis (TBL) coinfection in humans is a significant public health problem. We have previously shown that TBL+Ss+ coinfection significantly alters diverse cytokine,
Gokul Raj Kathamuthu +6 more
doaj +1 more source
Biotechnology Progress, EarlyView.Abstract Haptoglobin (Hp) is a polymorphic acute phase α‐2 glycoprotein found in plasma that plays a critical role in binding, neutralizing, and removing cell‐free hemoglobin (Hb) from the circulation. Under clinical conditions characterized by high levels of hemolysis, such as in patients with sickle cell disease (SCD), large quantities of cell‐free ...
Shuwei Lu +5 more
wiley +1 more source
Data in Brief, 2022 Hemorrhagic stroke is a major cause of morbidity and mortality worldwide. Secondary mechanisms of brain injury adversely affect functional outcome in patients after intracranial hemorrhage.
Kevin Akeret +3 more
doaj +1 more source
International Journal of Cancer, EarlyView.ABSTRACT Despite substantial clinical benefit from immune checkpoint inhibitors (ICI), advanced melanoma remains challenging due to frequent treatment resistance. Resistance may be intrinsic (primary) or emerge over time (secondary). Biomarkers predicting distinct resistance phenotypes before therapy are lacking.
Julian Kött +17 more
wiley +1 more source