Ontogeny of RSPO1, FOXL2, and RUNX1 during ovarian differentiation in the marsupial tammar wallaby
Developmental Dynamics, EarlyView.Abstract Background RSPO1 and FOXL2 are female sex‐determining genes involved in the differentiation and organization of the ovary in some eutherian mammals. Mutations or loss of function of these genes are associated with partial to full sex reversal in mice, humans, and goats.
Monika R. Paranjpe +3 more
wiley +1 more source
Molecules, 2019 The scope of this article is to provide a brief general introduction to heparan sulfate (HS) and heparin, and attempt to identify some of the central challenges regarding research into the chemistry and biology of glycosaminoglycans (GAGs), some of which
Edwin A Yates +2 more
doaj +1 more source
Partial purification and characterization of a heparan sulfate specific endoglucuronidase [PDF]
, 1976 Udo Klein, Kurt Von Figura
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Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, EarlyView.Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Degradation of heparan sulfate in the subendothelial extracellular matrix by a readily released heparanase from human neutrophils. Possible role in invasion through basement membranes. [PDF]
, 1985 Yaacov Matzner +5 more
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Molecular Nutrition &Food Research, EarlyView.We analyzed colostrum and breast milk from 47 mothers to see how proteins change over time and with maternal health. Colostrum had more immune proteins, while mature milk had proteins linked to growth support. Gestational diabetes and higher BMI altered the protein composition.
Timo Seitz +9 more
wiley +1 more source
Genomics and Histopathology in Interstitial Cystitis/Bladder Pain Syndrome
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims In April of 2025, a Global Consensus meeting on IC/BPS was held in Winston‐Salem, NC. The goal of this meeting was to establish global consensus in diagnostic criteria, phenotyping, treatment outcome assessment, and possible etiopathology in interstitial cystitis/bladder pain syndrome (IC/BPS).
Hannah Ruetten +4 more
wiley +1 more source
Basement membrane-like matrix of teratocarcinoma-derived endodermal cells: presence of laminin and heparan sulfate in the matrix at points of attachment to cells. [PDF]
, 1983 Ilmo Leivo
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Neuroprotection, EarlyView.Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai +3 more
wiley +1 more source
Research progress in the application of single‐cell sequencing technology in rheumatic diseases
Rheumatology &Autoimmunity, EarlyView.Application of single‐cell RNA sequencing (scRNA‐seq) technology in the study of the pathogenesis of rheumatic diseases. Tree of content illustration depicting the multi‐layered insights from scRNA‐seq in rheumatic diseases. The outer layer highlights key cell subsets identified by scRNA‐seq in rheumatoid arthritis, systemic lupus erythematosus ...
Xinzhe Feng +5 more
wiley +1 more source