Results 251 to 260 of about 84,900 (313)

Employing complementary fractionation‐based N‐terminomics approaches enhances the identification of legumain cleavage events in naïve and inflamed colon tissue

Protein Science, Volume 34, Issue 10, October 2025.
Abstract The mammalian lysosomal protease legumain is often dysregulated in pathophysiological conditions including inflammation, neurodegeneration, and cancer, yet its proteolytic targets are poorly defined. To profile protease substrates, degradomics techniques typically employ enrichment strategies to select for sub‐stoichiometric and low‐abundance ...
Alexander R. Ziegler, Benjamin L. Parker, Nichollas E. Scott, Laura E. Edgington‐Mitchell   +3 more
wiley   +1 more source

Heparin inhibition of insulin-like growth factor-binding protein-3 binding to human fibroblasts and rat glioma cells: role of heparan sulfate proteoglycans.

, 1996
Y W Yang, Masaki Yanagishita, Matthew M. Rechler   +2 more
openalex   +1 more source

Cell surface heparan sulfate is an attachment receptor for grass carp reovirus. [PDF]

iScience
Wang Q, Wang H, Wang X, Yang C, Li Y, Liao L, Zhu Z, Wang Y, He L.   +8 more
europepmc   +1 more source

Evidence for vitellogenin DNA‐binding in honey bees

Protein Science, Volume 34, Issue 10, October 2025.
Abstract DNA‐binding proteins play essential roles in DNA replication, DNA repair, DNA organization, and several aspects of gene regulation. Their well‐studied structures and charge configurations aid in identifying similar functions in other proteins. Vitellogenin (Vg) is a highly conserved protein that is central to egg‐yolk formation in most animal ...
Gyan Harwood, Vilde Leipart, Chris Elsik, Joseph C. F. Ng, Finn Drabløs, Gro V. Amdam   +5 more
wiley   +1 more source

Heparan Sulfate Proteoglycans in Neural Development.

, 1998
Yu Yamaguchi
openalex   +2 more sources

Unravelling structure-function interactions between fluorinated heparan sulfate mimetics and signaling proteins. [PDF]

RSC Chem Biol
Mahida V, Raigawali R, González P, Gimeno A, Leviatan Ben-Arye S, Anand S, Mardhekar S, Jiménez-Barbero J, Padler-Karavani V, Kikkeri R.   +9 more
europepmc   +1 more source

Survey of functional Mendelian variants in New Zealand Huntaway and Heading dog breeds

Animal Genetics, Volume 56, Issue 5, October 2025.
Abstract New Zealand (NZ) Huntaway and Heading dogs are working breeds that play active roles on farms across NZ. While these breeds are common in NZ, they are not well‐known elsewhere, and little is understood about their genetic make‐up. Here, we used whole genome sequencing to provide a comprehensive genomic view of 249 working dogs. As first use of
Florence Smith, Thomas Lopdell, Melissa Stephen, Millicent Henry, Keren Dittmer, Hayley Hunt, Nick Sneddon, Liam Williams, Jack Rolfe, Dorian Garrick, Mathew D. Littlejohn   +10 more
wiley   +1 more source

Presentation of CXCL12γ by heparan sulfate proteoglycans activates CXCR4 without desensitization in normal and malignant B cells. [PDF]

Blood Adv
Lantermans HC, Ma F, Kuil A, de Rooij MFM, Bergkamp ND, van der Meer W, van Buul JD, Smit MJ, Kersten MJ, Spaargaren M, Pals ST.   +10 more
europepmc   +1 more source

Group A Streptococcus interacts with glycosaminoglycans via M proteins to modulate bacterial adherence in vitro

The FEBS Journal, Volume 292, Issue 20, Page 5540-5562, October 2025.
Interactions between bacteria and the extracellular matrix are a prerequisite for colonisation and infection. Phylogenetically diverse M proteins of group A Streptococcus (GAS) can selectively bind sulfated glycosaminoglycans with high affinity. M protein‐mediated recruitment of chondroitin sulfate and dermatan sulfate was shown to increase GAS ...
Tahnee B.‐D. McEwan, David M. P. De Oliveira, Emily K. Stares, Lauren E. Hartley‐Tassell, Christopher J. Day, Mark J. Walker, Michael P. Jennings, Ronald Sluyter, Martina L. Sanderson‐Smith   +8 more
wiley   +1 more source

Role of Tie‐2 Axis in Sepsis: A Potential Therapeutic Target

Journal of Cellular and Molecular Medicine, Volume 29, Issue 20, October 2025.
ABSTRACT The angiopoietins (Angs)–Tie‐2 axis initiates signalling pathways that modulate vascular stability and angiogenesis and plays an important role in a variety of physiological and pathological processes, including inflammation, wound healing and cancer, by regulating endothelial cell proliferation, survival, migration, invasion and/or ...
Jun Feng, Junhui Liu, Xiaoyan Wu, Junshuai Wang   +3 more
wiley   +1 more source