Results 101 to 110 of about 17,189 (225)
Hepatic heparan sulfate is a master regulator of hepcidin expression and iron homeostasis in human hepatocytes and mice. [PDF]
, 2019 Hepcidin is a liver-derived peptide hormone that controls systemic iron homeostasis. Its expression is regulated by the bone morphogenetic protein 6 (BMP6)/SMAD1/5/8 pathway and by the proinflammatory cytokine interleukin 6 (IL6).
Anower-E-Khuda, Ferdous +8 more
core
Bench-to-bedside review: The role of glycosaminoglycans in respiratory disease. [PDF]
, 2006 The extracellular matrix (ECM) plays a significant role in the mechanical behaviour of the lung parenchyma. The ECM is composed of a three-dimensional fibre mesh that is filled with various macromolecules, among which are the glycosaminoglycans (GAGs ...
PELOSI P.P. +2 more
core +1 more source
Protein glycosylation in lung cancer from a mass spectrometry perspective
Mass Spectrometry Reviews, EarlyView.Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi +2 more
wiley +1 more source
Enterovirus 71 uses cell surface heparan sulfate glycosaminoglycan as an attachment receptor [PDF]
, 2013 Enterovirus 71 (EV-71) infections are usually associated with mild hand, foot, and mouth disease in young children but have been reported to cause severe neurological complications with high mortality rates.
Chan, Yoke Fun +3 more
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Molecular Nutrition &Food Research, EarlyView.We analyzed colostrum and breast milk from 47 mothers to see how proteins change over time and with maternal health. Colostrum had more immune proteins, while mature milk had proteins linked to growth support. Gestational diabetes and higher BMI altered the protein composition.
Timo Seitz +9 more
wiley +1 more source
Molecules, 2015 Angiogenesis, the process of formation of new blood vessel from pre-existing ones, is involved in various intertwined pathological processes including virus infection, inflammation and oncogenesis, making it a promising target for the development of ...
Paola Chiodelli +3 more
doaj +1 more source
Characterization of an Inhibitor of Neuronal Plasminogen Activator Released by Heart Cells [PDF]
, 1987 A basic understanding of growth cone dynamics and developmental events involving growth cones requires an understanding of the function and regulation of molecules associated with and released by growth cones. Rat sympathetic neurons in culture release a
Patterson, Paul H., Pittman, Randall N.
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Neuroprotection, EarlyView.Abstract Postoperative delirium (POD), a prevalent neurological complication in older surgical patients, adversely affects recovery. Isoflurane, a common inhalational anesthetic, exhibits neurotoxic potential, but its role in POD pathogenesis remains unclear.
Zhiming Dai +3 more
wiley +1 more source
Research progress in the application of single‐cell sequencing technology in rheumatic diseases
Rheumatology &Autoimmunity, EarlyView.Application of single‐cell RNA sequencing (scRNA‐seq) technology in the study of the pathogenesis of rheumatic diseases. Tree of content illustration depicting the multi‐layered insights from scRNA‐seq in rheumatic diseases. The outer layer highlights key cell subsets identified by scRNA‐seq in rheumatoid arthritis, systemic lupus erythematosus ...
Xinzhe Feng +5 more
wiley +1 more source
BMC Biotechnology, 2010 Background Heparan sulfate glycosaminoglycans are diverse components of certain proteoglycans and are known to interact with growth factors as a co-receptor necessary to induce signalling and growth factor activity.
Ellis April L +6 more
doaj +1 more source