Results 51 to 60 of about 17,189 (225)

Iron‐Catalyzed Highly Stereospecific Glycosylation with Glycal Epoxides

Angewandte Chemie, EarlyView.
We report an iron‐catalyzed, highly stereospecific glycosylation method with glycal epoxides, which is effective for a broad range of substrates, including previously challenging, sterically hindered secondary acceptors and glucuronic ester epoxide donors.
Xiao‐Wen Zhang, Le Yin, Dakang Zhang, Zixiang Jiang, Pinzhi Wang, Hao Xu   +5 more
wiley   +2 more sources

Lipolysis of very low density lipoproteins by heparan sulfate proteoglycan-bound lipoprotein lipase

Journal of Lipid Research, 1997
An in vitro assay to study lipolysis of very low density lipoproteins (VLDL) by heparan sulfate proteoglycan (HSPG-bound lipoprotein lipase (LPL) was developed.
F H de Man, F de Beer, A van der Laarse, A H Smelt, L M Havekes   +4 more
doaj   +1 more source

Syndecan-4 knockout leads to reduced extracellular transglutaminase-2 and protects against tubulointerstitial fibrosis [PDF]

, 2013
Transglutaminase type 2 (TG2) is an extracellular matrix crosslinking enzyme with a pivotal role in kidney fibrosis. The interaction of TG2 with the heparan sulfate proteoglycan syndecan-4 (Sdc4) regulates the cell surface trafficking, localization, and ...
Burhan, I, Funck, M, Huang, L, Johnson, TS, Scarpellini, A, Schroeder, N, Verderio, EAM   +6 more
core   +1 more source

Isolation and Characterization of Heparan Sulfate from Human Lung Tissues

Molecules, 2021
Glycosaminoglycans are a class of linear, highly negatively charged, O-linked polysaccharides that are involved in many (patho)physiological processes.
Rupert Derler, Nikola Kitic, Tanja Gerlza, Andreas J. Kungl   +3 more
doaj   +1 more source

Heparan sulfate proteoglycan is an important attachment factor for cell entry of Akabane and Schmallenberg viruses [PDF]

, 2017
Akabane (AKAV) and Schmallenberg (SBV) viruses are Orthobunyavirus transmitted by arthropod vectors with a broad cellular tropism in vitro as well as in vivo Both AKAV and SBV cause arthrogryposis-hydranencephaly syndrome in ruminants.
Horimoto, Taisuke, Kato, Kentaro, Kobayashi, Tomoya, Murakami, Shin, Palmarini, Massimo, Shimojima, Masayuki, Takenaka-Uema, Akiko   +6 more
core   +2 more sources

Developmental roles of heparan sulfate proteoglycans in Drosophila [PDF]

Glycoconjugate Journal, 2002
The formation of complex patterns in multi-cellular organisms is regulated by a number of signaling pathways. In particular, the Wnt and Hedgehog (Hh) pathways have been identified as critical organizers of pattern in many tissues. Although extensive biochemical and genetic studies have elucidated the central components of the signal transduction ...
Xinhua Lin, Norbert Perrimon
openaire   +3 more sources

The multifaceted roles of perlecan in fibrosis [PDF]

, 2018
Perlecan, or heparan sulfate proteoglycan 2 (HSPG2), is a ubiquitous heparan sulfate proteoglycan that has major roles in tissue and organ development and wound healing by orchestrating the binding and signaling of mitogens and morphogens to cells in a ...
Al-Ahmad, Andersson-Sjoland, Andersson-Sjoland, Arthur, Ashikari-Hada, Asplund, Aviezer, Barkefors, Barros, Behrens, Beller, Bengtsson, Bingley, Bishop, Bittencourt, Bix, Bix, Borkham-Kamphorst, Bremnes, Burgess, Cailhier, Cassiman, Celie, Ceol, Chakravarti, Chen, Chilosi, Chuang, Chuang, Cohen, Conde-Knape, Conte, Costell, Di Sario, Dos Santos, Duffield, Ebefors, Edgar, Esko, Evanko, Farach-Carson, Farach-Carson, Fengying Tang, Fernandez, Forsberg, Friedman, Friedman, Fujii, Gallai, Garl, Ge, Gellersen, Giros, Gohring, Gonzalez, Gonzalez, Goyal, Gressner, Gubbiotti, Guo, Hajari Case, Hallgren, Hammond, Hashimoto, Haubst, Hayashi, Hayward, Hedin, Hedin, Hering, Hilberg, Hisatomi, Ichimaru, Ikeguchi, Iozzo, Iozzo, Iozzo, Iredale, James G.W. Smith, James Melrose, Jelena Rnjak-Kovacina, John M. Whitelock, Jung, Kahari, Kaji, Kennett, Kinsella, Knox, Knox, Knox, Knox, Kotaru, Kovalszky, Koyama, Krimmer, Kunjathoor, Kvist, Laplante, Laplante, Leask, Leask, Leask, Lee, Lee, Lee, Lekkerkerker, Levy, Liang, Lord, Lord, Lord, Lord, Lundkvist, Mak, Mak, Mak, Malmstrom, Marra, Martinez-Hernandez, Martinez-Hernandez, Marx, Marzoll, Masola, Matsui, Matsuo, Megan S. Lord, Melrose, Melrose, Menzel, Mitra, Mollmark, Mongiat, Mongiat, Moon, Murphy, Musso, Nagy, Nakamura, Nakayama, Narita, Nguyen, Nihlberg, Nilsson, Ogawa, Ohkawara, Ozaki, Paka, Patel, Pillarisetti, Pinzani, Poluri, Pozzi, Raines, Raj, Rauch, Raymond, Rees, Rienstra, Rnjak-Kovacina, Rojkind, Rolls, Rosenzweig, Roskams, Ross, Sahin, Sakai, Salem, Sato, Schaefer, Schafer, Segev, Sharma, Shimizu-Hirota, Singh, Sofroniew, Sweeney, Tang, Tang, Tannock, Tao, Teh, Teimouri, Theret, Thomas, Thyberg, Timpl, Tomasek, Tran, Tran, Tran-Lundmark, Tátrai, Uchimura, Vanheule, Venkatesan, Venkatesan, Wang, Weiser, Weiser, Westergren-Thorsson, Westergren-Thorsson, Westergren-Thorsson, Whitelock, Whitelock, Whitelock, Whitelock, Willis, Wollin, Wollin, Woodall, Xu, Yamamoto, Yang, Yaoi, Yue, Yung, Yung, Zeisberg, Zeisberg   +217 more
core   +1 more source

Heparan sulfates and heparan sulfate proteoglycans in hematopoiesis

Blood
Abstract From signaling mediators in stem cells to markers of differentiation and lineage commitment to facilitators for the entry of viruses, such as HIV-1, cell surface heparan sulfate (HS) glycans with distinct modification patterns play important roles in hematopoietic biology.
Richard T. Piszczatowski, Hannes E. Bülow, Ulrich Steidl   +2 more
openaire   +2 more sources

Heparan sulfate proteoglycans: structure, protein interactions and cell signaling [PDF]

, 2009
Heparan sulfate proteoglycans are ubiquitously found at the cell surface and extracellular matrix in all the animal species. This review will focus on the structural characteristics of the heparan sulfate proteoglycans related to protein interactions ...
ABRAMSSON A, ALEXOPOULOU AN, ALLIEL PM, ALMEIDA PC, ARICESCU AR, ASHIKARI-HADA S, ATHANASSIADES A, AVIEZER D, BAEG GH, BAKER AB, BARTLETT AH, BEAUVAIS DM, BECKETT K, BELFORD DA, BELLIN R, BELTING M, BEN-ZAKEN O, BERNFIELD M, BEZAKOVA G, BLACKHALL FH, BOUCHE G, Caio V. Regatieri, CAIZERGUES-FERRER M, CAMPBELL EJ, CANO-GAUCI DF, CAPILA I, CAPILA I, CAPILA I, CAPURRO MI, CARDIN AD, CARNERO A, CASSARO CM, CASU B, CHAVANTE SF, CHEN CL, CHENG F, CHUANG WL, COHEN MM JR, COLE GJ, CONRAD HE, COOMBE DR, CROWN SE, CZUBAYKO F, DEANGELIS PL, DERKSEN PW, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETRICH CP, DIETZ F, DUCHESNE L, ESCRIBA PV, FAN TC, FARACH-CARSON MC, FARACH-CARSON MC, FEARS CY, FEDARKO NS, FERREIRA TM, FERRO DR, FEYZI E, FILMUS J, FILMUS J, FJELDSTAD K, FOX AN, FRANCO CR, FRANSSON LA, FRANSSON LA, FUKI IV, FUKI IV, FURUKAWA K, GAGLIARDI M, GALLAGHER JT, GAMBARINI AG, GIROS A, GITAY-GOREN H, GLASS DJ, GOMES PB, GRUNERT M, GUERRINI M, GUERRINI M, GUMIENNY TL, HABUCHI H, HACKER U, HANDEL TM, HARMER NJ, HARRISON CA, HAUSSER HJ, Helena B. Nader, HENKE CA, HILEMAN RE, HSIA E, HUBER R, IOZZO RV, IOZZO RV, ISHIHARA M, ISHIHARA M, ISHITSUKA R, JASTREBOVA N, JERONIMO SM, JIANG X, JOHNSON KG, JOHNSON Z, Juliana L. Dreyfuss, JURY EC, KAYED H, KEMP LE, KIRKPATRICK CA, KNOX SM, KOOPMANN W, KREUGER J, KRILLEKE D, LAU EK, LEICHT DT, LEWIS KA, LINDNER JR, LOO BM, LOPES CC, LOPES CC, LORTAT-JACOB H, Lucia O. Sampaio, MA YQ, MIYAZONO K, MOBLI M, MOHAMMADI M, MOHAMMADI M, MONGIAT M, MOREIRA CR, MORGAN MR, MULLOY B, MULLOY B, MULLOY B, MURRAY AJ, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NADER HB, NAKADA M, NASCIMENTO FD, NASCIMENTO FD, NG YS, NGO ST, NOTI C, NOZIK-GRAYCK E, NUGENT MA, NUNES SS, OBA-SHINJO SM, OH ES, PADERA R, PANKONIN MS, PARISH CR, PATEL VN, PATEY SJ, PELLEGRINI L, PERETTI T, POON GM, PORCIONATTO MA, PORCIONATTO MA, PORCIONATTO MA, POWELL AK, POWERS CJ, PRESTA M, QUARTO N, RAGAZZI M, RAMAN R, RAPRAEGER AC, RAPRAEGER AC, Renan P. Cavalheiro, RIDER CC, ROHDE LH, ROLNY C, RUBIN JS, RUHRBERG C, SAITO Y, SAKSELA O, SAMPAIO L, SANDERSON RD, SASAKI N, SASAKI S, SASISEKHARAN R, SCHNEPP A, SCHWALL RH, SHINJO SK, SMIRNOV SP, SONCIN F, SONG HH, SPIVAK-KROIZMAN T, STIGLIANO I, STRAUS AH, STRINGER SE, SU G, SUAREZ ER, SUGAYA N, SULPICE E, TANTRAVAHI RV, TAYLOR KR, TELCI D, TERSARIOL IL, TERSARIOL IL, Thais R. Jarrouge, TKACHENKO E, TKACHENKO E, TOLEDO OM, TOUROVSKAIA A, TRAISTER A, UTANI A, VEIGA SS, VEUGELERS M, VEUGELERS M, VIVES RR, VLODAVSKY I, WALKER A, WATT SM, WHITELOCK JM, WIEDLOCHA A, WILCOX-ADELMAN SA, WILKINS-PORT CE, WILLIAMS S, WOJTAL KA, WOODS A, WU DQ, YATES EA, YAYON A, YU WH, YU WH, ZHANG F   +227 more
core   +2 more sources

Microbial Subversion of Heparan Sulfate Proteoglycans

Molecules and Cells, 2008
The interactions between the host and microbial pathogen largely dictate the onset, progression, and outcome of infectious diseases. Pathogens subvert host components to promote their pathogenesis and, among these, cell surface heparan sulfate proteoglycans are exploited by many pathogens for their initial attachment and subsequent cellular entry.
Ye, Chen, Martin, Götte, Jian, Liu, Pyong Woo, Park   +3 more
openaire   +2 more sources