Results 101 to 110 of about 40,174 (273)

Role of Heparan Sulfate 2-O-Sulfotransferase in Prostate Cancer Cell Proliferation, Invasion, and Growth Factor Signaling

open access: yesProstate Cancer, 2011
Heparan-sulfate proteoglycans (HSPGs) are required for maximal growth factor signaling in prostate cancer progression. The degree of sulfate modification on the covalently attached heparan sulfate (HS) chains is one of the determining factors of growth ...
Brent W. Ferguson, Sumana Datta
doaj   +1 more source

Cancer Metastasis: The Role of the Extracellular Matrix and the Heparan Sulfate Proteoglycan Perlecan [PDF]

open access: gold, 2020
Zehra Elgundi   +6 more
openalex   +1 more source

Heparan Sulfate Proteoglycans in Infection

open access: yes, 2011
To cause infections, microbial pathogens elaborate a multitude of factors that interact with host components. Using these host–pathogen interactions to their advantage, pathogens attach, invade, disseminate, and evade host defense mechanisms to promote their survival in the hostile host environment.
Bartlett, Allison H., Park, Pyong Woo
openaire   +1 more source

Protein glycosylation in lung cancer from a mass spectrometry perspective

open access: yesMass Spectrometry Reviews, EarlyView.
Abstract Lung cancer is a severe disease for which better diagnostic and therapeutic approaches are urgently needed. Increasing evidence implies that aberrant protein glycosylation plays a crucial role in the pathogenesis and progression of lung cancer.
Mirjam Balbisi   +2 more
wiley   +1 more source

Collagens and proteoglycans of the corneal extracellular matrix

open access: yesBrazilian Journal of Medical and Biological Research, 2003
The cornea is a curved and transparent structure that provides the initial focusing of a light image into the eye. It consists of a central stroma that constitutes 90% of the corneal depth, covered anteriorly with epithelium and posteriorly with ...
Y.M. Michelacci
doaj   +1 more source

Elucidating glycosaminoglycan–protein–protein interactions using carbohydrate microarray and computational approaches [PDF]

open access: yes, 2011
Glycosaminoglycan polysaccharides play critical roles in many cellular processes, ranging from viral invasion and angiogenesis to spinal cord injury.
Bothwell   +39 more
core   +2 more sources

Heart‐On‐a‐Chip with Integrated Ultrasoft Mechanosensors for Continuous Measurement of Cell‐ and Tissue‐Scale Contractile Stresses

open access: yesSmall, EarlyView.
We present a heart‐on‐a‐chip platform embedded with ultrasoft mechanosensors for real‐time, multi‐scale stress mapping in engineered cardiac tissues. The system enables simultaneous quantification of local cell‐generated stresses and global tissue contractile forces.
Ali Mousavi   +10 more
wiley   +1 more source

Glycosaminoglycans and Glycosaminoglycan Mimetics in Cancer and Inflammation [PDF]

open access: yes, 2019
Glycosaminoglycans (GAGs) are a class of biomolecules expressed virtually on all mammalian cells and usually covalently attached to proteins, forming proteoglycans.
Morla, Shravan
core   +1 more source

Is Endothelial Nitric Oxide Synthase a Moonlighting Protein Whose Day Job is Cholesterol Sulfate Synthesis? Implications for Cholesterol Transport, Diabetes and Cardiovascular Disease [PDF]

open access: yes, 2012
Theoretical inferences, based on biophysical, biochemical, and biosemiotic considerations, are related here to the pathogenesis of cardiovascular disease, diabetes, and other degenerative conditions.
Ali   +35 more
core   +4 more sources

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