Results 191 to 200 of about 255,399 (229)

Enteroaggregative E. coli Adherence to Human Heparan Sulfate Proteoglycans Drives Segment and Host Specific Responses to Infection. [PDF]

open access: yesPLoS Pathog, 2020
Rajan A   +25 more
europepmc   +1 more source

Heparan sulfate proteoglycans in glomerular inflammation [PDF]

open access: yesKidney International, 2004
Heparan sulfate proteoglycans (HSPGs) are glycoproteins consisting of a core protein to which linear heparan sulfate side chains are covalently attached. These heparan sulfate side chains can be modified at different positions by several enzymes, which include N-deacetylases, N- and O-sulfotransferases, and an epimerase.
Johan Van Der Vlag   +2 more
exaly   +6 more sources

Microbial Subversion of Heparan Sulfate Proteoglycans

open access: yesMolecules and Cells, 2008
The interactions between the host and microbial pathogen largely dictate the onset, progression, and outcome of infectious diseases. Pathogens subvert host components to promote their pathogenesis and, among these, cell surface heparan sulfate proteoglycans are exploited by many pathogens for their initial attachment and subsequent cellular entry.
Pyong Woo Park, Martin Götte
exaly   +4 more sources

Heparan sulfate proteoglycans on the cell surface: versatile coordinators of cellular functions

open access: yesInternational Journal of Biochemistry and Cell Biology, 2000
Udgivelsesdato: 2000-MarHeparan sulfate proteoglycans are complex molecules composed of a core protein with covalently attached glycosaminoglycan chains.
Sarka Tumova   +2 more
exaly   +2 more sources

Heparan sulfate proteoglycans in invasion and metastasis

Seminars in Cell and Developmental Biology, 2001
Because heparan sulfate proteoglycans mediate cell adhesion and control the activities of numerous growth and motility factors, they play a critical role in regulating the metastatic behavior of tumor cells. Due to their utilitarian nature, heparan sulfate proteoglycans may at times act as inhibitors of cell invasion and at other times as promoters of ...
Ralph D Sanderson
exaly   +3 more sources

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