Results 201 to 210 of about 23,189 (236)

Heparan Sulfate Proteoglycans and Viral Attachment: True Receptors or Adaptation Bias? [PDF]

Viruses, 2019
Cagno V, Tseligka ED, Jones ST, Tapparel C.   +3 more
europepmc   +1 more source

Extracellular heparan sulfate proteoglycans and glycan-binding lectins orchestrate trans-synaptic signaling.

J Cell Sci, 2020
Rushton E, Kopke DL, Broadie K.
europepmc   +1 more source

Heparan sulfate proteoglycans regulate BMP signalling during neural crest induction.

Dev Biol, 2020
Pegge J, Tatsinkam AJ, Rider CC, Bell E.
europepmc   +1 more source

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Heparan sulfate proteoglycans in invasion and metastasis

Seminars in Cell and Developmental Biology, 2001
Because heparan sulfate proteoglycans mediate cell adhesion and control the activities of numerous growth and motility factors, they play a critical role in regulating the metastatic behavior of tumor cells. Due to their utilitarian nature, heparan sulfate proteoglycans may at times act as inhibitors of cell invasion and at other times as promoters of ...
Ralph D Sanderson
exaly   +3 more sources

Functions of Cell Surface Heparan Sulfate Proteoglycans

Annual Review of Biochemistry, 1999
▪ Abstract  The heparan sulfate on the surface of all adherent cells modulates the actions of a large number of extracellular ligands. Members of both cell surface heparan sulfate proteoglycan families, the transmembrane syndecans and the glycosylphosphoinositide-linked glypicans, bind these ligands and enhance formation of their receptor-signaling ...
M, Bernfield, M, Götte, P W, Park, O, Reizes, M L, Fitzgerald, J, Lincecum, M, Zako   +6 more
openaire   +3 more sources

Structural Properties of the Heparan Sulfate Proteoglycans of Brain

Journal of Neurochemistry, 1989
Abstract: The heparan sulfate proteoglycans present in a deoxycholate extract of rat brain were purified by ion exchange chromatography, affinity chromatography on lipoprotein lipase agarose, and gel filtration. Heparitinase treatment of the heparan sulfate proteoglycan fraction (containing 86% heparan sulfate and 10% chondroitin sulfate) that was ...
Richard U Margolis, J A Ripellino, R U Margolis   +2 more
exaly   +3 more sources

Heparan Sulfate Proteoglycans in Diabetes

Seminars in Thrombosis and Hemostasis, 2021
AbstractDiabetes is a complex disorder responsible for the mortality and morbidity of millions of individuals worldwide. Although many approaches have been used to understand and treat diabetes, the role of proteoglycans, in particular heparan sulfate proteoglycans (HSPGs), has only recently received attention.
openaire   +2 more sources

Heparan sulfate proteoglycans fine-tune macrophage inflammation via IFN-β [PDF]

Cytokine, 2015
Macrophages are important mediators of diseases associated with metabolic inflammation such as obesity and atherosclerosis. In this Stimulus we discuss recent findings showing that heparan sulfate proteoglycans on macrophages serve as an important ...
Philip L S M Gordts, Jeffrey D Esko
exaly   +3 more sources

Heparan Sulfate Proteoglycans in Amyloidosis

2010
Amyloidosis is a generic term for a group of diseases characterized by deposits in different organ systems of insoluble materials composed mainly of distinct fibrillar proteins named amyloid. Besides amyloid, heparan sulfate proteoglycan (HSPG), is commonly found in most amyloid deposits, suggesting that HS/HSPG may be functionally involved in the ...
Xiao, Zhang, Jin-Ping, Li
openaire   +2 more sources