Results 141 to 150 of about 44,737 (262)

Hepatic Stellate Cells Antagonize Sorafenib-Induced Ferroptosis in Hepatocellular Carcinoma by Upregulating the LINC00152/HSPB1 Axis. [PDF]

Cancers (Basel)
Li Y, Yin J, Fan R, Su J, Yi J, Wang H, Yao B.   +6 more
europepmc   +1 more source

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Hepatic stellate cells in liver fibrosis: From biology to pathology. [PDF]

Open Vet J
Esselmani H, Nadir Y, Ennadi R, Zouhairi N, Hiba OE, Lkousse MA, Najimi M, Merzouki M.   +7 more
europepmc   +1 more source

Cross‐Species Single‐Cell Comparative Analysis Reveals Gluconeogenic Features of Hepatocytes in Ruminants

Animal Research and One Health, EarlyView.
In this study, we used cross‐species comparisons to identify ruminant hepatocyte features. We also identified potential genes and TFs involved in coordinating gluconeogenesis in ruminant hepatocytes. By integrating single‐cell data with population genetic analyses, we further identified candidate genetic variation in glucose metabolism and ...
Yaqi Zhou, Wuqiang Huo, Yingran Liu, Yihang Liu, Fei Wang, Tao Shi, Yu Jiang   +6 more
wiley   +1 more source

Sirtuin five knockdown induced the ferroptosis of hepatic stellate cells in hepatic fibrosis progression through de-succinylation modification of GPX4. [PDF]

J Biol Chem
Zhou J, Zhang J, Zheng S, Zhu J, Wang K, Guo X.   +5 more
europepmc   +1 more source

CD248/Endosialin Regulates Synovial Fibroblast State to Control Coupling of Inflammation and Bone Damage in Murine Models of Immune‐Mediated Inflammatory Arthritis and Aging

Arthritis &Rheumatology, EarlyView.
Objective Synovial fibroblasts directly contribute to inflammation and damage in immune‐mediated inflammatory arthritis. CD248/endosialin is expressed by fibroblasts in the synovium, is highly up‐regulated during inflammation, and has been proposed as a potential therapeutic target.
Samuel Kemble, Corinna Wehmeyer, James M. Brown, Charlotte G. Smith, Holly R. Adams, Eva Crombie, Ellie Northall, Maryam Imran, Paulynn Chin, Harris R. Perlman, Christopher D. Buckley, Adam P. Croft, Amy J. Naylor   +12 more
wiley   +1 more source

Today's hepatic stellate cells [PDF]

Hepatology, 2007
Erick P. Chan, Rebecca G. Wells, Kris Kowdley, Geoffrey McCaughan, Christian Trautwein   +4 more
openaire   +2 more sources

A Novel Anti-Fibrotic Role of G-Protein-Coupled Receptor 119 in Hepatic Stellate Cells. [PDF]

Biomol Ther (Seoul)
Park J, Lee MH, Kim HY, Kim HS, Kim SK, Yang JW, Kang KW.   +6 more
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Resmetirom Ameliorates Fibrogenesis in Hepatic Stellate Cells via Thyroid Hormone Receptor Alpha-Fatty-Acid Amide Hydrolase 1 Signaling Pathway. [PDF]

MedComm (2020)
Novoa E, Cabaleiro A, López-Picallo B, Lima NDS, Riobello C, Pena C, Iglesias-Moure J, Senra A, Martínez-Chantar ML, Fernandez-Iglesias A, Gracia-Sancho J, Bravo S, Dieguez C, Varela-Rey M, Prevot V, Schwaninger M, López M, Nogueiras R.   +17 more
europepmc   +1 more source