Results 191 to 200 of about 44,737 (262)

Tomatidine modulatesfibrosis-related markers by promoting autophagy in hepatic stellate cells via the ERK/MAPK-mTOR-ULK1 signaling pathway. [PDF]

Sci Rep
Fan Y, Zhang Y, Li W, Du Y, Song Y, Wang J, Tang B, Deng F, Cheng L.   +8 more
europepmc   +1 more source

Safety and Metabolic Effects of Withania somnifera Seed Extract and Powder in Rats: Insights From DPP‐4 Molecular Docking

Food Safety and Health, EarlyView.
Withania somnifera seed extract and powder improved metabolic parameters in rats, particularly at higher extract doses, without evident hepatic, renal, hematological, or histopathological toxicity. Molecular docking further predicted strong DPP‐4 inhibitory potential of withanone, supporting the antidiabetic potential of W. somnifera seeds.
Muhammad Usman Khalid, Muhammad Waqar, Muhammad Tauseef Sultan, Muhammad Maaz, Ahmad Mujtaba Noman, Hassan Raza, Muhammad Israr, Djilali Benabdelmoumene, Abdifetah Ibrahim Omar   +8 more
wiley   +1 more source

EMP1 + hepatic stellate cells drive hepatic fibrosis progression to hepatocellular carcinoma and predict prognosis. [PDF]

J Transl Med
You J, Huang Y, Jiang C, Xiao J, Zhang J, Liu Y, Sui X, Zhang Y, Yao J, Lu T.   +9 more
europepmc   +1 more source

Citrus Essential Oils in Food Safety and Health: Advances in AI‐Assisted Authentication, Antimicrobial Applications, Sustainable Extraction, and Regulatory Translation

Food Safety and Health, EarlyView.
Citrus essential oils combine sustainable extraction, AI‐assisted authentication, multi‐omics profiling, antimicrobial activity, and regulatory safety to enhance food quality, detect adulteration, and promote consumer health, and support intelligent, sustainable food systems through innovative industrial applications and circular bioeconomy strategies.
Md. Hassan Bin Nabi, Liza Akter, Yusuf Chowdhury, Mohima Akther Any, Nazmul Islam, Erni Sofia Murtini, Nurul Huda, Wahidu Zzaman   +7 more
wiley   +1 more source

Carvedilol triggers ferroptosis in hepatic stellate cells via the ATF4/SAT1 axis promoting spermidine depletion to ameliorate liver fibrosis. [PDF]

Cell Death Dis
Xia Y, Wang S, Zhu J, Chen Y, Liu X, Zhang C.   +5 more
europepmc   +1 more source

Treatment‐Related Adverse Events and Health‐Related Quality of Life Associated With Immune Checkpoint Inhibitor Treatment for Mucosal Head and Neck Squamous Cell Carcinoma: A Scoping Review

Head &Neck, EarlyView.
ABSTRACT Background Supportive care needs of patients receiving immune checkpoint inhibitors (ICIs) for head and neck squamous cell carcinoma (HNSCC) are ill‐defined. Hence, known treatment‐related adverse events (TRAEs) and health‐related quality of life (HRQoL) associated with ICI treatment for HNSCC were examined to inform future supportive care ...
N. D. O'Donnell, E. C. Ward, L. R. Wishart, R. Perera, C. Barrett, K. A. Edmiston, E. Mitchell, A. Pigott, R. Pitt, K. Russell, B. A. Chan, R. Ladwa   +11 more
wiley   +1 more source

Lecithin-Retinol Acyltransferase-Cre Exhibits Widespread Expression Beyond Hepatic Stellate Cells Across Multiple Tissues. [PDF]

Gastro Hep Adv
Kim K, Taleb S, So J, Wann J, Roh HC.
europepmc   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

Head &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou, Pooja D. Reddy, Purva H. Rumde, Mary L. Klem, Sagar G. Kansara, Oldrich Virag, Yvonne M. Mowery, Nicole N. Scheff, Matthew E. Spector, Shaum Sridharan, Marci L. Nilsen, Kevin J. Contrera   +11 more
wiley   +1 more source

Effect of free fatty acids on TGF-β1 mediated fibrogenesis in hepatic stellate cells. [PDF]

Mol Metab
De Nardo W, Bayliss J, Elahee Doomun SN, Lee O, Miotto PM, Suriani ND, Nie S, Leeming M, Miranda DA, De Souza DP, Watt MJ.   +10 more
europepmc   +1 more source

Non-transcriptional activity of IRF3 promotes liver fibrosis and stress granule assembly via a dsRNA-TLR3-dependent pathway in hepatic stellate cells. [PDF]

Hepatology
Travers J, Zhang Y, Cajigas-Du Ross CK, Huang E, McMullen MR, Wu J, Paouri E, Davalos D, Wu X, Pathak V, Rotroff DM, Nagy LE.   +11 more
europepmc   +1 more source