Results 251 to 260 of about 411,384 (307)
p16<sup>Ink4a</sup>-Positive Hepatocytes Drive Liver Fibrosis Through Activation of LIFR Family Pathway. [PDF]
Adv Sci (Weinh)Nishikawa K +23 more
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ATP6V1B2 alleviates hepatic steatosis by promoting lysosomal acidification in hepatocytes. [PDF]
Cell Death DiscovXu R +7 more
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Single-cell RNA sequencing combined with single-cell genome-wide association study identifies SF3B4 as a hub gene in hepatocellular carcinoma progression. [PDF]
Discov OncolMa F +5 more
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Replenishing hepatocytes [PDF]
Nature Reviews Gastroenterology and Hepatology, 2018 Katrina Ray
exaly +3 more sources
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Biochemical Society Transactions, 2000
Hepatocyte couplets, by retaining functional and morphological polarity similar to that of hepatocytes in situ, are a valuable in vitro model to study mechanisms of bile secretion, cholestasis and hepatocellular injury. They have been useful in studies of the hormonal control of bile formation and are suitable for morphological studies.
R, Coleman, M G, Roma
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Hepatocyte couplets, by retaining functional and morphological polarity similar to that of hepatocytes in situ, are a valuable in vitro model to study mechanisms of bile secretion, cholestasis and hepatocellular injury. They have been useful in studies of the hormonal control of bile formation and are suitable for morphological studies.
R, Coleman, M G, Roma
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Comprehensive Physiology, 2013
Abstract Hepatocytes, like other epithelia, are situated at the interface between the organism's exterior and the underlying internal milieu and organize the vectorial exchange of macromolecules between these two spaces. To mediate this function, epithelial cells, including hepatocytes, are polarized with distinct
Aleksandr, Treyer, Anne, Müsch
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Abstract Hepatocytes, like other epithelia, are situated at the interface between the organism's exterior and the underlying internal milieu and organize the vectorial exchange of macromolecules between these two spaces. To mediate this function, epithelial cells, including hepatocytes, are polarized with distinct
Aleksandr, Treyer, Anne, Müsch
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2006
Isolated hepatocytes are a physiologically relevant in vitro model exhibiting intact subcellular organelles, xenobiotic transport, and integrated phase I and phase II biotransformation. They represent the "gold standard" for investigating xenobiotic biotransformation and metabolic bioactivation.
Elaut, Greetje +6 more
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Isolated hepatocytes are a physiologically relevant in vitro model exhibiting intact subcellular organelles, xenobiotic transport, and integrated phase I and phase II biotransformation. They represent the "gold standard" for investigating xenobiotic biotransformation and metabolic bioactivation.
Elaut, Greetje +6 more
openaire +3 more sources
Microencapsulating Hepatocytes
Transplantation Proceedings, 2005Because standardization of the cell microencapsulation procedure has not yet been achieved, we performed hepatocyte microencapsulation using alginate (ALG)-poly-l-lysine (PLL)-ALG (APA) polymer.Hepatocytes were microencapsulated using a binozzle air-jet droplet generator.
Y, Gao +4 more
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Current Protocols in Toxicology, 2001
AbstractThis unit describes a process for isolation of intact, viable hepatocytes for use in integrated drug metabolism studies. Isolated hepatocytes are increasingly being used as a biological system for studying the in vitro metabolism of xenobiotics.
D R, Mudra, A, Parkinson
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AbstractThis unit describes a process for isolation of intact, viable hepatocytes for use in integrated drug metabolism studies. Isolated hepatocytes are increasingly being used as a biological system for studying the in vitro metabolism of xenobiotics.
D R, Mudra, A, Parkinson
openaire +2 more sources