Results 261 to 270 of about 628,453 (389)

Strategies to inhibit entry of HBV and HDV into hepatocytes.

Gastroenterology, 2014
S. Urban, R. Bartenschlager, R. Kubitz, F. Zoulim   +3 more
semanticscholar   +1 more source

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

TRIM16 mediates YAP1 K63-linked ubiquitination to alleviate sepsis-induced acute liver injury through YAP/Nrf2 axis in mice. [PDF]

Cell Biosci
Zhang K, Liu M, Zheng Y, Gao Z, Dong Z, You M, Guo Y, Liang F, Zhao Z.   +8 more
europepmc   +1 more source

Hepatotrophic properties in dogs of human FKBP, the binding protein for FK506 and rapamycin [PDF]

, 1991
Albers, MW, Foglieni, CS, Francavilla, A, Porter, KA, Schreiber, SL, Starzl, TE   +5 more
core   +1 more source

Ultrasound‐Boosted Liposomal Prodrug Overcomes Age‐Associated Biodistribution Disparity in Pediatric Solid Tumor Therapy

Advanced Science, EarlyView.
The age‐associated disparity of nanocarrier biodistribution limits the nanotherapeutics of childhood solid tumors. This study developed an ultrasound‐activated liposomal prodrug (CSCPTL) to overcome the age‐associated disparity of off‐target distribution.
Danfei Chen, Junjun Xu, Jian Chen, Jue Hu, Xiaobo Xuan, Haifang Cai, Mingdong Yang, Zhuxian Zhou, Guowei Wang   +8 more
wiley   +1 more source

Development of a DNA damage assay system using stable human hepatocytes. [PDF]

Genes Environ
Mishima M, Izawa K, Tsuda M, Higuchi Y, Uehara S, Suemizu H, Sugiyama KI.   +6 more
europepmc   +1 more source

Bacterial lipopolysaccharide antagonizes transforming growth factor β1-induced apoptosis in primary cultures of hepatocytes [PDF]

, 1996
Paloma Martı́n-Sanz, María José Guerra Palmero, Marta Casado, Lisardo Boscá   +3 more
openalex   +1 more source

PDIA3 Inhibition Facilitates Sensitivity of IKE‐Induced Ferroptosis via STAT3/LCN2 Axis to Improve Glioblastoma Therapy

Advanced Science, EarlyView.
In this manuscript, protein disulfide isomerase A3 (PDIA3) is identified as a key factor mediating the susceptibility of ferroptosis in GBM. Inhibition of PDIA3 enhances IKE or cystine starvation‐induced ferroptosis in GBM cells by resulting in the accumulation of lipid peroxidation and a reduction in GSH level.
Jie Zhang, Wei Wang, Xin Liu, Peifen Lu, Xinjing Liu, Qiucheng Nie, Siyuan Xin, Hong Li, Donglin Yu, Xinyue Zhang, Kailong Li, Xiaomin Han, Shuping Zhang, Wei Chong, Lili Sun, Wei Li, Tao Xin, Jin Jiao, Qiang Ma, Yiju Wei   +19 more
wiley   +1 more source

Exploring key genes in NAFLD linked to glutamine metabolism: A comprehensive analysis combining multi-omics, machine learning and SHAP. [PDF]

Asia Pac J Clin Nutr
Chen C, Liu W, Lan Y, Li F, Li X.
europepmc   +1 more source

Determination of liver specific toxicities in rat hepatocytes by high content imaging during 2-week multiple treatment

, 2014
Davide Germano, Marianne Uteng, François Pognan, Salah‐Dine Chibout, Armin Wolf   +4 more
openalex   +1 more source