Results 271 to 280 of about 628,453 (389)

Higher Serum Hepatocyte Growth Factor Concentration is Associated with Better Preservation of GFR in Hemodialysis Patients [PDF]

, 2017
Ewa Baum, Beata Maćkowiak, Patrycja Sosińska, Krzysztof Pawlaczyk, Barbara Kołodziejczak, Andrzej Bręborowicz   +5 more
openalex   +1 more source

Derivation of hepatocytes from bone marrow cells in mice after radiation‐induced myeloablation

Hepatology, 2000
N. Theise, S. Badve, R. Saxena, O. Henegariu, S. Sell, J. M. Crawford, D. Krause   +6 more
semanticscholar   +1 more source

Uncoupling Metastasis and Epithelial‐to‐Mesenchymal Transition in sgP19/kRAS‐Driven Spontaneous Metastatic Liver Tumor Model

Advanced Science, EarlyView.
The article first reported that a murine mixed typical intrahepatic cholangiocarcinoma (iCCA)/sarcomatoid iCCA liver tumor model with 100% incidence of spontaneous extrahepatic metastasis and confirmed the occurrence of in mouse iCCA. Most importantly, EMT induced by the TGF‐β/ZEB1 axis does not influence tumor development or distant metastasis in this
Jingwen Wang, Zijing Xu, Lei Xu, Lishan Wang, Jiahao Geng, Xue Wang, Meng Xu, Daphne Superville, Melissa Reeves, Matthias Evert, Diego F. Calvisi, Xin Chen, Xinhua Song   +12 more
wiley   +1 more source

Hepatic Hypoxia-Inducible Factor 1α Mediates Ferroptosis via Transferrin Receptor 1 in Acute Liver Injury. [PDF]

Antioxidants (Basel)
Yang J, Wang M, Cui S, Xia Y, Xie Y, Hu Z, Li N, Zhang X, Zhu P, Yu X, Wu L, Li J.   +11 more
europepmc   +1 more source

Microcystin‐LR Triggers Renal Tubular Ferroptosis Through Epigenetic Repression of GPX4: Implications for Environmental Nephrotoxicity

Advanced Science, EarlyView.
MC‐LR stabilizes DNMT1/3a by blocking their ubiquitin‐mediated degradation, leading to Gpx4 promoter hypermethylation and E2F4/NCoR‐associated transcriptional repression, which drives renal tubular ferroptosis in mice. Pharmacological inhibition of DNA methylation (SGI‐1027) or ferroptosis (Fer‐1) disrupts this DNMT‐GPX4 axis, thereby alleviating MC‐LR‐
Shaoru Zhang, Qi Gao, Yi Peng, Huan Zhang, Qi Shen, Meihong Guo, Yuqing Gong, Lei Chu, Weidong Wu, Yanting Wen, Wangsen Cao, Yong Wang, Lihui Wang   +12 more
wiley   +1 more source

Oleic Acid Increases Lipid Accumulation in Duck Hepatocytes by Promoting Apolipoprotein A1 Expression. [PDF]

Animals (Basel)
Pan Z, Li X, Wu D, Xie L, Chen X, Geng Z.   +5 more
europepmc   +1 more source

Transforming growth factor beta signaling in hepatocytes participates in steatohepatitis through regulation of cell death and lipid metabolism in mice

Hepatology, 2014
Ling Yang, Y. Roh, Jingyi Song, Bi Zhang, Cheng Liu, R. Loomba, E. Seki   +6 more
semanticscholar   +1 more source

Forsythoside E Alleviates Liver Injury by Targeting PKM2 Tetramerization to Promote Macrophage M2 Polarization

Advanced Science, EarlyView.
Here, the study shows for the first time that Forsythoside E (FE) can promote PKM2 tetramerization by binding to its K311 site. Furthermore, it induces metabolic reprogramming of macrophages and inhibits NLRP3 expression. Finally, it can alleviate sepsis‐induced liver injury by promoting M2 anti‐inflammatory polarization.
Bingxin Wu, Xuechun Yu, Yanling Li, Lin An, Rongrong Zhang, Rong Zhang, Fan Zhang, Zhongqiu Liu, Caiyan Wang   +8 more
wiley   +1 more source

Hepatocyte production across embryonic stages in chicken: an in vitro approach. [PDF]

BMC Vet Res
Farzaneh M, Azizidoost S.
europepmc   +1 more source

Uric acid induces fat accumulation via generation of endoplasmic reticulum stress and SREBP-1c activation in hepatocytes

Laboratory Investigation, 2014
Yea-Jin Choi, Hyun-Soo Shin, H. Choi, J. Park, I. Jo, E. Oh, Kang‐Yo Lee, Byung-Hoon Lee, Richard J. Johnson, D. Kang   +9 more
semanticscholar   +1 more source