Results 91 to 100 of about 34,396 (232)
Experimental Physiology, EarlyView.Abstract Ski mountaineering (SkiMo) is a new Olympic sport with extreme endurance demands and altitude exposure. Previous studies have focused on traditional cardiorespiratory variables, such as maximal oxygen consumption (V̇O2max${\dot V_{{{\mathrm{O}}_{\mathrm{2}}}{\mathrm{max}}}}$) or ventilatory thresholds, but, to our knowledge, did not report ...
Forrest Schorderet +7 more
wiley +1 more source
Interaction of hemojuvelin with neogenin results in iron accumulation in human embryonic kidney 293 cells [PDF]
, 2005 Type 2 hereditary hemochromatosis (HH) or juvenile hemochromatosis is an early onset, genetically heterogeneous, autosomal recessive disorder of iron overload.
Bjorkman, Pamela J. +4 more
core +1 more source
Serum hepcidin in clinical specimens [PDF]
British Journal of Haematology, 2003 Summary. The hepatic antimicrobial protein, hepcidin, is implicated in duodenal iron absorption and mobilization. Overexpression of the hepcidin gene is associated with a hypoferraemic, microcytic, iron‐refractory anaemia. On the basis of these observations, it has been proposed that hepcidin is a mediator of the common clinical syndrome, anaemia of ...
Gail, Dallalio +2 more
openaire +2 more sources
Hypoxia and hypercapnia elicit overlapping but distinct skeletal muscle toxicities
The Journal of Physiology, EarlyView.Abstract figure legend Hypoxia and hypercapnia cause overlapping skeletal muscle phenotypes, including atrophy, change in myofibre metabolic profile and myogenic response to injury. Both signals operate via distinct cellular pathways. Abstract Skeletal muscle dysfunction is strongly associated with elevated mortality in acute and chronic pulmonary ...
Joseph Balnis, Ariel Jaitovich
wiley +1 more source
Expression and cellular localization of hepcidin mRNA and protein in normal rat brain. [PDF]
, 2015 BACKGROUND: Hepcidin is a peptide hormone belonging to the defensin family of cationic antimicrobial molecules that has an essential role in systemic iron homeostasis. The peptide is synthesised by hepatocytes and transported in the circulation to target
Adrian Bomford +6 more
core +1 more source
Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3254-3263, April 2026.Abstract Aims Sotagliflozin, an inhibitor of sodium‐glucose co‐transporter (SGLT)‐1 and 2, reduces albuminuria, slows GFR decline, and may have diuretic and osmoregulatory effects. The effect of sotagliflozin added to insulin was assessed on markers of neurohormone activation and volume homeostasis in patients with type 1 diabetes (T1D).
Massimo Nardone +6 more
wiley +1 more source
Subcutaneous Adipose Tissue from Obese and Lean Adults Does Not Release Hepcidin In Vivo
The Scientific World Journal, 2011 Hepcidin is the main regulator of systemic iron homeostasis and is primarily produced by the liver but is also expressed, at the mRNA-level, in periphery tissues including the subcutaneous and visceral adipose tissue.
Lisa Tussing-Humphreys +7 more
doaj +1 more source
Rusty microglia: trainers of innate immunity in Alzheimer's disease [PDF]
, 2018 Alzheimer's disease, the most common form of dementia, is marked by progressive cognitive and functional impairment believed to reflect synaptic and neuronal loss.
Adonis Sfera +6 more
core +2 more sources
Alzheimer's &Dementia, Volume 22, Issue 3, March 2026.Abstract Emerging evidence highlights the central role of peripheral immune–metabolic regulation in the pathogenesis of Alzheimer's disease and related dementias (ADRD). Among peripheral organs, the spleen has gained increasing attention as a critical immune–metabolic hub linking systemic homeostasis to central neurodegeneration.
Jingsi Yan +7 more
wiley +1 more source